8EI3
Crystal structure of VHL in complex with H313, a Helicon Polypeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Elongin-B | polymer | 118 | 13147.8 | 2 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 2 | B, E (B, E) | Elongin-C | polymer | 96 | 10843.4 | 2 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | EloC, Elongin 15 kDa subunit, RNA polymerase II transcription factor SIII subunit C, SIII p15, Transcription elongation factor B polypeptide 1 |
| 3 | C, F (C, F) | von Hippel-Lindau disease tumor suppressor | polymer | 163 | 18840.4 | 2 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (human) | Protein G7,pVHL |
| 4 | G (G) | H313 | polymer | 19 | 1968.2 | 1 | synthetic construct | ||
| 5 | H (G) | N,N'-(1,4-phenylene)diacetamide | non-polymer | 192.2 | 1 | Chemie (WHL) |
Sequence modifications
C, F: 54 - 213 (UniProt: P40337)
| PDB | External Database | Details |
|---|---|---|
| Gly 51 | - | expression tag |
| Ser 52 | - | expression tag |
| His 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 87631.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 192.2 | |
| All* | Total formula weight | 87823.7 |
