1EJO
 
 | | FAB FRAGMENT OF NEUTRALISING MONOCLONAL ANTIBODY 4C4 COMPLEXED WITH G-H LOOP FROM FMDV. | | Descriptor: | FMDV PEPTIDE, IGG2A MONOCLONAL ANTIBODY (HEAVY CHAIN), IGG2A MONOCLONAL ANTIBODY (LIGHT CHAIN) | | Authors: | Ochoa, W.F, Kalko, S.G, Gomes, P, Fita, I, Verdaguer, N. | | Deposit date: | 2000-03-03 | | Release date: | 2000-03-22 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules.
J.Gen.Virol., 81, 2000
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2PUS
 | | Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase | | Descriptor: | IBDV VP1 RNA-dependant RNA polymerase | | Authors: | Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N. | | Deposit date: | 2007-05-09 | | Release date: | 2007-11-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QJ1
 | | Crystal structure of infectious bursal disease virus VP1 polymerase incubated with an oligopeptide mimicking the VP3 C-terminus | | Descriptor: | Infectious bursal disease virus VP1 polymerase | | Authors: | Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N. | | Deposit date: | 2007-07-06 | | Release date: | 2007-11-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.48 Å) | | Cite: | Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase
To be Published
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2R70
 | | Crystal structure of infectious bursal disease virus VP1 polymerase, cocrystallized with an oligopeptide mimicking the VP3 C-terminus. | | Descriptor: | INFECTIOUS BURSAL VIRUS VP1 POLYMERASE | | Authors: | Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N. | | Deposit date: | 2007-09-07 | | Release date: | 2007-11-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R18
 | | Structural insights into the multifunctional protein VP3 of Birnaviruses | | Descriptor: | Capsid assembly protein VP3 | | Authors: | Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N. | | Deposit date: | 2007-08-22 | | Release date: | 2008-02-05 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural insights into the multifunctional protein VP3 of birnaviruses.
Structure, 16, 2008
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3J3I
 | | Penicillium chrysogenum virus (PcV) capsid structure | | Descriptor: | Capsid protein | | Authors: | Luque, D, Gomez-Blanco, J, Garriga, D, Brilot, A, Gonzalez, J.M, Havens, W.H, Carrascosa, J.L, Trus, B.L, Verdaguer, N, Grigorieff, N, Ghabrial, S.A, Caston, J.R. | | Deposit date: | 2013-03-08 | | Release date: | 2014-05-14 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Cryo-EM near-atomic structure of a dsRNA fungal virus shows ancient structural motifs preserved in the dsRNA viral lineage.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3KMQ
 | | G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, tetragonal structure | | Descriptor: | 3D polymerase, RNA (5'-R(*GP*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*CP*C)-3') | | Authors: | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | | Deposit date: | 2009-11-11 | | Release date: | 2010-07-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3KMS
 | | G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure | | Descriptor: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | | Authors: | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | | Deposit date: | 2009-11-11 | | Release date: | 2010-07-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3KOA
 | | M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA and GTP | | Descriptor: | 3D polymerase, DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | | Deposit date: | 2009-11-13 | | Release date: | 2010-07-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3KNA
 | | M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA | | Descriptor: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | | Authors: | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | | Deposit date: | 2009-11-12 | | Release date: | 2010-07-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3KLV
 | | M296I G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA | | Descriptor: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | | Authors: | Ferrer-Orta, C, Sierra, M, Agudo, R, Perez-Luque, R, Arias, A, Verdaguer, N. | | Deposit date: | 2009-11-09 | | Release date: | 2010-07-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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2D7S
 | | Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein | | Descriptor: | RNA-dependent RNA polymerase, VPg1 protein | | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | | Deposit date: | 2005-11-29 | | Release date: | 2006-03-28 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The structure of a protein primer-polymerase complex in the initiation of genome replication
Embo J., 25, 2006
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4L3B
 | | X-ray structure of the HRV2 A particle uncoating intermediate | | Descriptor: | Protein VP1, Protein VP2, Protein VP3 | | Authors: | Vives-Adrian, L, Querol-Audi, J, Garriga, D, Pous, J, Verdaguer, N. | | Deposit date: | 2013-06-05 | | Release date: | 2013-11-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (6.5 Å) | | Cite: | Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3DPR
 | | Human rhinovirus 2 bound to a concatamer of the VLDL receptor module V3 | | Descriptor: | CALCIUM ION, LAURIC ACID, LDL-receptor class A 3, ... | | Authors: | Querol-Audi, J, Pous, J, Fita, I, Verdaguer, N. | | Deposit date: | 2008-07-09 | | Release date: | 2009-04-07 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition
Febs Lett., 583, 2009
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3GF5
 | | Crystal structure of the P21 R1-R7 N-terminal domain of murine MVP | | Descriptor: | GLYCEROL, Major vault protein | | Authors: | Querol-Audi, J, Casanas, A, Luque, D, Caston, J.R, Fita, I, Verdaguer, N. | | Deposit date: | 2009-02-26 | | Release date: | 2009-11-10 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP
Embo J., 28, 2009
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4NZ0
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3GNG
 | | P21B crystal structure of R1-R7 of Murine MVP | | Descriptor: | Major vault protein | | Authors: | Querol-Audi, J, Casanas, A, Uson, I, Caston, J.R, Fita, I, Verdaguer, N. | | Deposit date: | 2009-03-17 | | Release date: | 2009-11-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP
Embo J., 28, 2009
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2F8E
 | | Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein | | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... | | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | | Deposit date: | 2005-12-02 | | Release date: | 2006-03-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The structure of a protein primer-polymerase complex in the initiation of genome replication
Embo J., 25, 2006
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3FBM
 | | D431N Mutant VP2 Protein of Infectious Bursal Disease Virus; Derived T=1 Particles | | Descriptor: | CALCIUM ION, Polyprotein | | Authors: | Irigoyen, N, Garriga, D, Navarro, A, Verdaguer, N, Rodriguez, J.F, Caston, J.R. | | Deposit date: | 2008-11-19 | | Release date: | 2009-01-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Autoproteolytic Activity Derived from the Infectious Bursal Disease Virus Capsid Protein
J.Biol.Chem., 284, 2009
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3GNF
 | | P1 Crystal structure of the N-terminal R1-R7 of murine MVP | | Descriptor: | Major vault protein | | Authors: | Querol-Audi, J, Casanas, A, Uson, I, Luque, D, Caston, J.R, Fita, I, Verdaguer, N. | | Deposit date: | 2009-03-17 | | Release date: | 2009-11-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP
Embo J., 28, 2009
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5M2X
 | | Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033) | | Descriptor: | NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N. | | Deposit date: | 2016-10-13 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (4.991 Å) | | Cite: | Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
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5M2Z
 | | Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033) | | Descriptor: | NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N. | | Deposit date: | 2016-10-13 | | Release date: | 2018-06-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (4.8 Å) | | Cite: | Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
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4NP9
 | | Structure of Rabphilin C2A domain bound to IP3 | | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rabphilin-3A, SULFATE ION | | Authors: | Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-Sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S. | | Deposit date: | 2013-11-21 | | Release date: | 2013-12-25 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4NYZ
 | | The EMCV 3Dpol structure with altered motif A conformation at 2.15A resolution | | Descriptor: | GLUTAMINE, GLYCEROL, Genome polyprotein, ... | | Authors: | Vives-adrian, L, Lujan, C, Ferrer-orta, C, Verdaguer, N. | | Deposit date: | 2013-12-11 | | Release date: | 2014-03-19 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
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3GPE
 | | Crystal Structure Analysis of PKC (alpha)-C2 domain complexed with Ca2+ and PtdIns(4,5)P2 | | Descriptor: | CALCIUM ION, PHOSPHATE ION, Protein kinase C alpha type, ... | | Authors: | Ferrer-Orta, C, Querol-Audi, J, Fita, I, Verdaguer, N. | | Deposit date: | 2009-03-23 | | Release date: | 2009-05-05 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proc.Natl.Acad.Sci.USA, 106, 2009
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