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PDB: 143 件

7K43
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SARS-CoV-2 spike in complex with the S2M11 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2M11 Fab fragment (heavy chain), ...
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-14
公開日2020-10-07
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 370, 2020
5TX1
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Cryo-Electron microscopy structure of species-D human adenovirus 26
分子名称: Fiber, Hexon protein, PIIIa, ...
著者Reddy, V, Yu, X, Veesler, D.
登録日2016-11-15
公開日2017-05-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses.
Sci Adv, 3, 2017
5SZS
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Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Walls, A.C, Tortorici, M.A, Frenz, B, Snijder, J, Li, W, Rey, F.A, DiMaio, F, Bosch, B.J, Veesler, D.
登録日2016-08-15
公開日2016-09-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy.
Nat.Struct.Mol.Biol., 23, 2016
5V4S
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CryoEM Structure of a Prokaryotic Cyclic Nucleotide-Gated Ion Channel
分子名称: Transporter, cation channel family / cyclic nucleotide-binding domain multi-domain protein
著者James, Z.M, Borst, A.J, Haitin, Y, Frenz, B, DiMaio, F, Zagotta, W.N, Veesler, D.
登録日2017-03-10
公開日2017-04-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7JZL
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SARS-CoV-2 spike in complex with LCB1 (2RBDs open)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCB1, ...
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-02
公開日2020-09-23
最終更新日2020-11-04
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Science, 370, 2020
6NB3
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MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ...
著者Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-12-06
公開日2019-02-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB7
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SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ...
著者Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-12-06
公開日2019-02-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB4
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MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ...
著者Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-12-06
公開日2019-02-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
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BU of 6nb6 by Molmil
SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ...
著者Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-12-06
公開日2019-02-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB5
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BU of 6nb5 by Molmil
Crystal structure of anti- MERS-CoV human neutralizing LCA60 antibody Fab fragment
分子名称: LCA60 antigen-binding (Fab) fragment, heavy chain, light chain
著者Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-12-06
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6Q04
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BU of 6q04 by Molmil
MERS-CoV S structure in complex with 5-N-acetyl neuraminic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-01
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
6NB8
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BU of 6nb8 by Molmil
Crystal structure of anti- SARS-CoV human neutralizing S230 antibody Fab fragment
分子名称: S230 antigen-binding (Fab) fragment, heavy chain, light chain
著者Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-12-06
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6Q06
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BU of 6q06 by Molmil
MERS-CoV S structure in complex with 2,3-sialyl-N-acetyl-lactosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-01
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
6Q05
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BU of 6q05 by Molmil
MERS-CoV S structure in complex with sialyl-lewisX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-01
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
6Q07
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BU of 6q07 by Molmil
MERS-CoV S structure in complex with 2,6-sialyl-N-acetyl-lactosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-01
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
6NZK
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BU of 6nzk by Molmil
Structural basis for human coronavirus attachment to sialic acid receptors
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ...
著者Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D.
登録日2019-02-13
公開日2019-06-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
6OHW
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Structural basis for human coronavirus attachment to sialic acid receptors. Apo-HCoV-OC43 S
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ...
著者Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D.
登録日2019-04-07
公開日2019-06-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
8TVG
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BU of 8tvg by Molmil
Langya henipavirus postfusion F protein in complex with the 4G5 Fab, local refinement of the viral membrane distal region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya henipavirus postfusion F protein
著者Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-08-18
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVF
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BU of 8tvf by Molmil
Langya henipavirus fusion protein in prefusion state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya henipavirus fusion protein in prefusion state, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Wang, Z, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-08-18
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVB
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Ghanaian virus fusion glycoprotein (GhV F)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-08-17
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVI
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BU of 8tvi by Molmil
Langya Virus G glycoprotein (LayV G) with stabilizing mutations
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya virus attachment glycoprotein G, ZINC ION
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-08-18
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVE
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BU of 8tve by Molmil
Langya henipavirus fusion protein in postfusion state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya henipavirus fusion protein in postfusion state
著者Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-08-18
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VGT
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BU of 8vgt by Molmil
Structure of the HKU1 RBD bound to the human TMPRSS2 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-12-27
公開日2024-03-06
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Human coronavirus HKU1 recognition of the TMPRSS2 host receptor.
Cell, 2024
8TVH
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Langya henipavirus postfusion F protein in complex with 4G5 Fab, local refinement of the viral membrane proximal region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4G5 heavy chain, 4G5 light chain, ...
著者Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-08-18
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
7U0A
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Crystal Structure of C77G12 Fab in complex with SARS-CoV-2 S fusion peptide
分子名称: CHLORIDE ION, Heavy chain Fab C77G12, Light chain Fab C77G12, ...
著者Tortorici, M.A, Veesler, D.
登録日2022-02-17
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022

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