6NB7
| SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NB4
| MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NB6
| SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NB3
| MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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4IOS
| Structure of phage TP901-1 RBP (ORF49) in complex with nanobody 11. | 分子名称: | BPP, GLYCEROL, Llama nanobody 11 | 著者 | Desmyter, A, Farenc, C, Mahony, J, Spinelli, S, Bebeacua, C, Blangy, S, Veesler, D, van Sinderen, D, Cambillau, C. | 登録日 | 2013-01-08 | 公開日 | 2013-03-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Viral infection modulation and neutralization by camelid nanobodies Proc.Natl.Acad.Sci.USA, 110, 2013
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3JCL
| Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer | 分子名称: | Spike glycoprotein | 著者 | Walls, A.C, Tortorici, M.A, Bosch, B.J, Frenz, B, Rottier, P.J.M, DiMaio, F, Rey, F.A, Veesler, D. | 登録日 | 2015-12-21 | 公開日 | 2016-02-03 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer. Nature, 531, 2016
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7K43
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6NB5
| Crystal structure of anti- MERS-CoV human neutralizing LCA60 antibody Fab fragment | 分子名称: | LCA60 antigen-binding (Fab) fragment, heavy chain, light chain | 著者 | Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NB8
| Crystal structure of anti- SARS-CoV human neutralizing S230 antibody Fab fragment | 分子名称: | S230 antigen-binding (Fab) fragment, heavy chain, light chain | 著者 | Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NZK
| Structural basis for human coronavirus attachment to sialic acid receptors | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ... | 著者 | Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D. | 登録日 | 2019-02-13 | 公開日 | 2019-06-05 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for human coronavirus attachment to sialic acid receptors. Nat.Struct.Mol.Biol., 26, 2019
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6OHW
| Structural basis for human coronavirus attachment to sialic acid receptors. Apo-HCoV-OC43 S | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ... | 著者 | Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D. | 登録日 | 2019-04-07 | 公開日 | 2019-06-05 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for human coronavirus attachment to sialic acid receptors. Nat.Struct.Mol.Biol., 26, 2019
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6C5V
| An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ... | 著者 | Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-01-16 | 公開日 | 2018-05-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus. Immunity, 48, 2018
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8U29
| Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ... | 著者 | Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2023-09-05 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus. Cell Host Microbe, 31, 2023
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8U0T
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7JZL
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6VYB
| SARS-CoV-2 spike ectodomain structure (open state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Walls, A.C, Park, Y.J, Tortorici, M.A, Wall, A, Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T, Veesler, D. | 登録日 | 2020-02-25 | 公開日 | 2020-03-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell, 181, 2020
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6VXX
| Structure of the SARS-CoV-2 spike glycoprotein (closed state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Walls, A.C, Park, Y.J, Tortorici, M.A, Wall, A, Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T, Veesler, D. | 登録日 | 2020-02-25 | 公開日 | 2020-03-11 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell, 181, 2020
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6AVR
| Human alpha-V beta-3 Integrin (intermediate conformation) in complex with the therapeutic antibody LM609 | 分子名称: | Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ... | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | 登録日 | 2017-09-04 | 公開日 | 2017-11-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (35 Å) | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance. Structure, 25, 2017
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6AVQ
| The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha-V beta-3 Integrin via Steric Hindrance | 分子名称: | Integrin alpha-V, Integrin beta-3, LM609 Fab heavy chain, ... | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | 登録日 | 2017-09-04 | 公開日 | 2017-11-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (35 Å) | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance. Structure, 25, 2017
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6AVU
| Human alpha-V beta-3 Integrin (open conformation) in complex with the therapeutic antibody LM609 | 分子名称: | Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ... | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | 登録日 | 2017-09-04 | 公開日 | 2017-11-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (35 Å) | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance. Structure, 25, 2017
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6B3O
| Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion | 分子名称: | Spike glycoprotein | 著者 | Walls, A.C, Tortorici, M.A, Snijder, J, Xiong, X, Bosch, B.J, Rey, F.A, Veesler, D. | 登録日 | 2017-09-22 | 公開日 | 2017-10-04 | 最終更新日 | 2020-01-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6BDF
| 2.8 A resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy | 分子名称: | Proteasome subunit alpha, Proteasome subunit beta | 著者 | Campbell, M.G, Veesler, D, Cheng, A, Potter, C.S, Carragher, B. | 登録日 | 2017-10-23 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | 2.8 angstrom resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy. Elife, 4, 2015
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6BFU
| Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, ... | 著者 | Xiong, X, Tortorici, M.A, Snijder, S, Yoshioka, C, Walls, A.C, Li, W, Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T, Rey, F.A, Bosch, B.J, Veesler, D. | 登録日 | 2017-10-27 | 公開日 | 2017-11-22 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections. J. Virol., 92, 2018
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6Q04
| MERS-CoV S structure in complex with 5-N-acetyl neuraminic acid | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ... | 著者 | Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2019-08-01 | 公開日 | 2019-12-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors. Nat.Struct.Mol.Biol., 26, 2019
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6Q06
| MERS-CoV S structure in complex with 2,3-sialyl-N-acetyl-lactosamine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ... | 著者 | Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2019-08-01 | 公開日 | 2019-12-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors. Nat.Struct.Mol.Biol., 26, 2019
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