6NZK

Structural basis for human coronavirus attachment to sialic acid receptors

Summary for 6NZK

• Entry DOI: 10.2210/pdb6nzk/pdb
• EMDB information: 0557
• Descriptor: Spike surface glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: coronavirus spike glycoprotein, sialic acid, hcov-oc43, fusion protein, viral protein
• Biological source: Human coronavirus OC43 (HCoV-OC43)
• Total number of polymer chains: 3
• Total formula weight: 460838.89

Authors

Tortorici, M.A.,Walls, A.C.,Lang, Y.,Wang, C.,Li, Z.,Koerhuis, D.,Boons, G.J.,Bosch, B.J.,Rey, F.A.,de Groot, R.,Veesler, D. (deposition date: 2019-02-13, release date: 2019-06-05, Last modification date: 2020-07-29)

• Primary citation: Alejandra Tortorici, M.,Walls, A.C.,Lang, Y.,Wang, C.,Li, Z.,Koerhuis, D.,Boons, G.J.,Bosch, B.J.,Rey, F.A.,de Groot, R.J.,Veesler, D.; Structural basis for human coronavirus attachment to sialic acid receptors.; Nat.Struct.Mol.Biol., 26:481-489, 2019; PubMed: 31160783; DOI: 10.1038/s41594-019-0233-y

Experimental method

ELECTRON MICROSCOPY (2.8 Å)