6RKW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rkw by Molmil](/molmil-images/mine/6rkw) | CryoEM structure of the complete E. coli DNA Gyrase complex bound to a 130 bp DNA duplex | Descriptor: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA (58-MER), DNA (62-MER), ... | Authors: | Vanden Broeck, A, Lamour, V. | Deposit date: | 2019-04-30 | Release date: | 2019-11-06 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
|
|
7MQA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mqa by Molmil](/molmil-images/mine/7mqa) | Cryo-EM structure of the human SSU processome, state post-A1 | Descriptor: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Vanden Broeck, A, Singh, S, Klinge, S. | Deposit date: | 2021-05-05 | Release date: | 2021-09-22 | Last modified: | 2021-09-29 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
|
|
7MQ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mq9 by Molmil](/molmil-images/mine/7mq9) | Cryo-EM structure of the human SSU processome, state pre-A1* | Descriptor: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Vanden Broeck, A, Singh, S, Klinge, S. | Deposit date: | 2021-05-05 | Release date: | 2021-09-22 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
|
|
7MQ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mq8 by Molmil](/molmil-images/mine/7mq8) | Cryo-EM structure of the human SSU processome, state pre-A1 | Descriptor: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Vanden Broeck, A, Singh, S, Klinge, S. | Deposit date: | 2021-05-05 | Release date: | 2021-09-22 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
|
|
6RKV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rkv by Molmil](/molmil-images/mine/6rkv) | |
6RKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rks by Molmil](/molmil-images/mine/6rks) | E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 without TOPRIM insertion | Descriptor: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA Strand 1, DNA Strand 2, ... | Authors: | Vanden Broeck, A, Lamour, V. | Deposit date: | 2019-04-30 | Release date: | 2019-11-06 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
|
|
6RKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rku by Molmil](/molmil-images/mine/6rku) | E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 | Descriptor: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA Strand 1, DNA Strand 2, ... | Authors: | Vanden Broeck, A, Lamour, V. | Deposit date: | 2019-04-30 | Release date: | 2019-11-06 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
|
|
6ZY7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zy7 by Molmil](/molmil-images/mine/6zy7) | Cryo-EM structure of the entire Human topoisomerase II alpha in State 1 | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | Authors: | Vanden Broeck, A, Lamour, V. | Deposit date: | 2020-07-30 | Release date: | 2021-05-26 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.64 Å) | Cite: | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
|
|
6ZY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zy6 by Molmil](/molmil-images/mine/6zy6) | Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 2 | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | Authors: | Vanden Broeck, A, Lamour, V. | Deposit date: | 2020-07-30 | Release date: | 2021-05-26 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
|
|
6ZY8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zy8 by Molmil](/molmil-images/mine/6zy8) | Cryo-EM structure of the entire Human topoisomerase II alpha in State 2 | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | Authors: | Vanden Broeck, A, Lamour, V. | Deposit date: | 2020-07-30 | Release date: | 2021-05-26 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
|
|
6ZY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zy5 by Molmil](/molmil-images/mine/6zy5) | Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 1 | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | Authors: | Vanden Broeck, A, Lamour, V. | Deposit date: | 2020-07-30 | Release date: | 2021-05-26 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
|
|
6ENH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6enh by Molmil](/molmil-images/mine/6enh) | |
6ENG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6eng by Molmil](/molmil-images/mine/6eng) | Crystal structure of the 43K ATPase domain of Escherichia coli gyrase B in complex with an aminocoumarin | Descriptor: | CHLORIDE ION, Coumermycin A1, DNA gyrase subunit B, ... | Authors: | Vanden Broeck, A, McEwen, A.G, Lamour, V. | Deposit date: | 2017-10-04 | Release date: | 2019-04-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for DNA Gyrase Interaction with Coumermycin A1. J.Med.Chem., 62, 2019
|
|
4BZG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bzg by Molmil](/molmil-images/mine/4bzg) | Crystal structure of galactose mutarotase GalM from Bacillus subtilis in complex with maltose | Descriptor: | ALDOSE 1-EPIMERASE, CITRIC ACID, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | Deposit date: | 2013-07-25 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis in Complex with Maltose To be Published
|
|
4BZH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bzh by Molmil](/molmil-images/mine/4bzh) | Crystal structure of galactose mutarotase GalM from Bacillus subtilis in complex with maltose and trehalose | Descriptor: | ALDOSE 1-EPIMERASE, CITRIC ACID, GLYCEROL, ... | Authors: | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | Deposit date: | 2013-07-25 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis in Complex with Maltose and Trehalose To be Published
|
|
4BZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bzf by Molmil](/molmil-images/mine/4bzf) | Crystal structure of galactose mutarotase GalM from Bacillus subtilis with trehalose | Descriptor: | ACETATE ION, ALDOSE 1-EPIMERASE, CITRIC ACID, ... | Authors: | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | Deposit date: | 2013-07-25 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis with Trehalose To be Published
|
|
4BZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bze by Molmil](/molmil-images/mine/4bze) | Crystal structure of galactose mutarotase GalM from Bacillus subtilis | Descriptor: | ALDOSE 1-EPIMERASE, CITRIC ACID, GLYCEROL | Authors: | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | Deposit date: | 2013-07-25 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis To be Published
|
|
8FL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fl9 by Molmil](/molmil-images/mine/8fl9) | |
8FKV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fkv by Molmil](/molmil-images/mine/8fkv) | |
8FKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fkr by Molmil](/molmil-images/mine/8fkr) | |
8FLA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fla by Molmil](/molmil-images/mine/8fla) | |
8FL4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fl4 by Molmil](/molmil-images/mine/8fl4) | |
8FKT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fkt by Molmil](/molmil-images/mine/8fkt) | |
8FL7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fl7 by Molmil](/molmil-images/mine/8fl7) | |
8FLE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fle by Molmil](/molmil-images/mine/8fle) | |