3IGC
 
 | | Smallpox virus topoisomerase-DNA transition state | | Descriptor: | 5'-D(*AP*TP*TP*CP*C)-3', 5'-D(*CP*GP*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', ... | | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | Deposit date: | 2009-07-27 | | Release date: | 2010-03-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic.
Structure, 18, 2010
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4OJR
 | | Crystal Structure of the HIV-1 Integrase catalytic domain with GSK1264 | | Descriptor: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, CACODYLATE ION, HIV-1 Integrase, ... | | Authors: | Gupta, K, Brady, T, Dyer, B, Hwang, Y, Male, F, Nolte, R.T, Wang, L, Velthuisen, E, Jeffrey, J, Van Duyne, G, Bushman, F.D. | | Deposit date: | 2014-01-21 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Allosteric Inhibition of Human Immunodeficiency Virus Integrase: LATE BLOCK DURING VIRAL REPLICATION AND ABNORMAL MULTIMERIZATION INVOLVING SPECIFIC PROTEIN DOMAINS.
J.Biol.Chem., 289, 2014
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4GLI
 | | Crystal Structure of Human SMN YG-Dimer | | Descriptor: | Maltose-binding periplasmic protein, Survival motor neuron protein chimera | | Authors: | Martin, R.S, Perry, K, Van Duyne, G.D. | | Deposit date: | 2012-08-14 | | Release date: | 2012-10-17 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.903 Å) | | Cite: | The survival motor neuron protein forms soluble glycine zipper oligomers.
Structure, 20, 2012
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1CRX
 | | CRE RECOMBINASE/DNA COMPLEX REACTION INTERMEDIATE I | | Descriptor: | CRE RECOMBINASE, DNA (5'-D(*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*G)-3'), ... | | Authors: | Guo, F, Gopaul, D.N, Van Duyne, G.D. | | Deposit date: | 1997-07-02 | | Release date: | 1998-10-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse.
Nature, 389, 1997
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3C28
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3BVP
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2H7G
 | | Structure of variola topoisomerase non-covalently bound to DNA | | Descriptor: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*TP*A)-3', DNA topoisomerase 1 | | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | Deposit date: | 2006-06-02 | | Release date: | 2006-08-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
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2H7F
 | | Structure of variola topoisomerase covalently bound to DNA | | Descriptor: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', DNA topoisomerase 1 | | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | Deposit date: | 2006-06-02 | | Release date: | 2006-08-15 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
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2HOF
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2HOI
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1XNS
 | | Peptide trapped Holliday junction intermediate in Cre-loxP recombination | | Descriptor: | Recombinase CRE, loxP DNA | | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | | Deposit date: | 2004-10-05 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.
J.Biol.Chem., 280, 2005
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1Y96
 | | crystal structure of the Gemin6/Gemin7 heterodimer from the human SMN complex | | Descriptor: | Gem-associated protein 6, Gem-associated protein 7 | | Authors: | Ma, Y, Dostie, J, Dreyfuss, G, Van Duyne, G.D. | | Deposit date: | 2004-12-14 | | Release date: | 2005-06-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.002 Å) | | Cite: | The Gemin6-Gemin7 Heterodimer from the Survival of Motor Neurons Complex Has an Sm Protein-like Structure.
Structure, 13, 2005
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1XO0
 | | High resolution structure of the holliday junction intermediate in cre-loxp site-specific recombination | | Descriptor: | Recombinase CRE, loxP | | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | | Deposit date: | 2004-10-05 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.
J.Biol.Chem., 280, 2005
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2LEH
 | | Solution structure of the core SMN-Gemin2 complex | | Descriptor: | Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1 | | Authors: | Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G. | | Deposit date: | 2011-06-15 | | Release date: | 2012-06-27 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the core SMN-Gemin2 complex.
Biochem.J., 445, 2012
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