7KIT
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2H0T
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2H10
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2H0Y
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2H5S
| SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase | 分子名称: | (3R)-4-[(4-CARBOXYBUTANOYL)OXY]-N-[(1E)-3-OXOPROP-1-EN-1-YL]-3-SULFINO-D-VALINE, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, SHV-1 beta-lactamase | 著者 | van den Akker, F, Padayatti, P.S. | 登録日 | 2006-05-27 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Rational Design of a beta-Lactamase Inhibitor Achieved via Stabilization of the trans-Enamine Intermediate: 1.28 A Crystal Structure of wt SHV-1 Complex with a Penam Sulfone. J.Am.Chem.Soc., 128, 2006
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3V5M
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1DP4
| DIMERIZED HORMONE BINDING DOMAIN OF THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATRIAL NATRIURETIC PEPTIDE RECEPTOR A, ... | 著者 | van den Akker, F, Zhang, X, Miyagi, M, Huo, X, Misono, K.S, Yee, V.C. | 登録日 | 1999-12-23 | 公開日 | 2000-07-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the dimerized hormone-binding domain of a guanylyl-cyclase-coupled receptor. Nature, 406, 2000
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2P08
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2P04
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4DXB
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4DXC
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4GD6
| SHV-1 beta-lactamase in complex with penam sulfone SA1-204 | 分子名称: | (3R)-N-(2-formylindolizin-3-yl)-4-[(phenylacetyl)oxy]-3-sulfino-D-valine, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE | 著者 | van den Akker, F, Wei, K. | 登録日 | 2012-07-31 | 公開日 | 2013-07-31 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Structures of SHV-1 beta-lactamase with penem and penam sulfone inhibitors that form cyclic intermediates stabilized by carbonyl conjugation Plos One, 7, 2012
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4R3B
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5IXX
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5IXR
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5IXV
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5IXZ
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5IXW
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8SDV
| Crystal structure of PDC-3 Y221H beta-lactamase in complex with the boronic acid inhibitor S02030 | 分子名称: | 1-{(2R)-2-(dihydroxyboranyl)-2-[(thiophen-2-ylacetyl)amino]ethyl}-1H-1,2,3-triazole-4-carboxylic acid, Beta-lactamase, DIMETHYL SULFOXIDE, ... | 著者 | Kumar, V, van den Akker, F. | 登録日 | 2023-04-07 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase. Antimicrob.Agents Chemother., 67, 2023
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8SDN
| Crystal structure of PDC-3 Y221H beta-lactamase | 分子名称: | Beta-lactamase, ISOPROPYL ALCOHOL | 著者 | Kumar, V, van den Akker, F. | 登録日 | 2023-04-07 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase. Antimicrob.Agents Chemother., 67, 2023
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8SDR
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8SDT
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8SDL
| Crystal structure of PDC-3 beta-lactamase | 分子名称: | Beta-lactamase, IMIDAZOLE, ISOPROPYL ALCOHOL | 著者 | Kumar, V, van den Akker, F. | 登録日 | 2023-04-07 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase. Antimicrob.Agents Chemother., 67, 2023
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8SDS
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5EE8
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