2W58
| Crystal Structure of the DnaI | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Tsai, K.L, Lo, Y.H, Sun, Y.J, Hsiao, C.D. | 登録日 | 2008-12-08 | 公開日 | 2009-12-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular Interplay between the Replicative Helicase Dnac and its Loader Protein Dnai from Geobacillus Kaustophilus. J.Mol.Biol., 393, 2009
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6XI8
| Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ... | 著者 | van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L. | 登録日 | 2020-06-19 | 公開日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Structure of TFIIK for phosphorylation of CTD of RNA polymerase II. Sci Adv, 7, 2021
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8TQ2
| Structure of the kinase lobe of human CDK8 kinase module | 分子名称: | Cyclin-C, Cyclin-dependent kinase 8, Mediator of RNA polymerase II transcription subunit 12, ... | 著者 | Chen, S.F, Chao, T.C, Kim, H.J, Tang, H.C, Khadka, S, Li, T, Murakami, K, Boyer, T.G, Tsai, K.L. | 登録日 | 2023-08-06 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol.Cell, 2024
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8TQC
| Structure of the human CDK8 kinase module | 分子名称: | Cyclin-C, Cyclin-dependent kinase 8, Mediator of RNA polymerase II transcription subunit 12, ... | 著者 | Chen, S.F, Chao, T.C, Kim, H.J, Tang, H.C, Khadka, S, Li, T, Murakami, K, Boyer, T.G, Tsai, K.L. | 登録日 | 2023-08-06 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol.Cell, 2024
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8TQW
| Structure of human transcriptional Mediator complex | 分子名称: | Cyclin-C, Cyclin-dependent kinase 8, Mediator of RNA polymerase II transcription subunit 1, ... | 著者 | Chen, S.F, Chao, T.C, Kim, H.J, Tang, H.C, Khadka, S, Li, T, Murakami, K, Boyer, T.G, Tsai, K.L. | 登録日 | 2023-08-08 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | 主引用文献 | Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol.Cell, 2024
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8TRH
| The IDRc bound human core Mediator complex | 分子名称: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... | 著者 | Chen, S.F, Chao, T.C, Kim, H.J, Tang, H.C, Khadka, S, Li, T, Murakami, K, Boyer, T.G, Tsai, K.L. | 登録日 | 2023-08-09 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol.Cell, 2024
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2VYF
| Crystal Structure of the DnaC | 分子名称: | GOLD ION, REPLICATIVE DNA HELICASE | 著者 | Lo, Y.H, Tsai, K.L, Sun, Y.J, Hsiao, C.D. | 登録日 | 2008-07-23 | 公開日 | 2008-12-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The Crystal Structure of a Replicative Hexameric Helicase Dnac and its Complex with Single-Stranded DNA. Nucleic Acids Res., 37, 2009
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2VYE
| Crystal Structure of the DnaC-ssDNA complex | 分子名称: | 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP)-3', REPLICATIVE DNA HELICASE | 著者 | Lo, Y.H, Tsai, K.L, Sun, Y.J, Hsiao, C.D. | 登録日 | 2008-07-23 | 公開日 | 2008-12-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | The Crystal Structure of a Replicative Hexameric Helicase Dnac and its Complex with Single-Stranded DNA. Nucleic Acids Res., 37, 2009
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7KPW
| Structure of the H-lobe of yeast CKM | 分子名称: | Mediator of RNA polymerase II transcription subunit 12 | 著者 | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | 登録日 | 2020-11-12 | 公開日 | 2021-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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7KPV
| Structure of kinase and Central lobes of yeast CKM | 分子名称: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | 著者 | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | 登録日 | 2020-11-12 | 公開日 | 2021-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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7KUE
| CryoEM structure of Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ... | 著者 | van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L. | 登録日 | 2020-11-24 | 公開日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of TFIIK for phosphorylation of CTD of RNA polymerase II. Sci Adv, 7, 2021
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3RJ1
| Architecture of the Mediator Head module | 分子名称: | Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... | 著者 | Imasaki, T, Calero, G, Cai, G, Tsai, K.L, Yamada, K, Cardelli, F, Erdjument-Bromage, H, Tempst, P, Berger, I, Kornberg, G.L, Asturias, F.J, Kornberg, R.D, Takagi, Y. | 登録日 | 2011-04-14 | 公開日 | 2011-07-27 | 最終更新日 | 2017-08-02 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Architecture of the Mediator head module. Nature, 475, 2011
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7KPX
| Structure of the yeast CKM | 分子名称: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | 著者 | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | 登録日 | 2020-11-12 | 公開日 | 2021-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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6AUI
| Human ribonucleotide reductase large subunit (alpha) with dATP and CDP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Brignole, E.J, Drennan, C.L, Asturias, F.J, Tsai, K.L, Penczek, P.A. | 登録日 | 2017-09-01 | 公開日 | 2018-04-18 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | 3.3- angstrom resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. Elife, 7, 2018
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7UIC
| Mediator-PIC Early (Tail A) | 分子名称: | Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, Mediator of RNA polymerase II transcription subunit 16, ... | 著者 | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | 登録日 | 2022-03-29 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UIL
| Mediator-PIC Early (Tail A/B Dimer) | 分子名称: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, ... | 著者 | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | 登録日 | 2022-03-29 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UIF
| Mediator-PIC Early (Core B) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | 登録日 | 2022-03-29 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UIK
| Mediator-PIC Early (Tail A + Upstream DNA & Activator) | 分子名称: | DNA (37-MER), DNA (38-MER), Mediator of RNA polymerase II transcription subunit 14, ... | 著者 | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | 登録日 | 2022-03-29 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UIO
| Mediator-PIC Early (Composite Model) | 分子名称: | ALANINE, ASPARTIC ACID, DNA (37-MER), ... | 著者 | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | 登録日 | 2022-03-29 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UIG
| Mediator-PIC Early (Mediator A) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ... | 著者 | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | 登録日 | 2022-03-29 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UI9
| Core Mediator-PICearly (Copy A) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | 登録日 | 2022-03-28 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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