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PDB: 36 results

8FV7
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E coli. CTP synthase in complex with dF-dCTP + ATP
Descriptor: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, ...
Authors:Holyoak, T, McLeod, M.J, Tran, N.
Deposit date:2023-01-18
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
6F5Z
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Complex between the Haloferax volcanii Trm112 methyltransferase activator and the Hvo_0019 putative methyltransferase
Descriptor: 24-sterol C-methyltransferase, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Graille, M, van Tran, N.
Deposit date:2017-12-04
Release date:2018-07-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes.
Nucleic Acids Res., 46, 2018
6H2V
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Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase at 2.5A resolution
Descriptor: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:van Tran, N, Graille, M.
Deposit date:2018-07-16
Release date:2019-07-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.
Nucleic Acids Res., 47, 2019
6S6H
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Crystal structure of the DNA binding domain of the chromosome-partitioning protein ParB complexed to the centromeric parS site
Descriptor: Chromosome-partitioning protein ParB, DNA (5'-D(*GP*AP*TP*GP*TP*TP*TP*CP*AP*CP*GP*TP*GP*AP*AP*AP*CP*AP*TP*C)-3'), GLYCEROL
Authors:Jalal, A.S.B, Tran, N.T, Stevenson, C.E.M, Tan, E.X, Lawson, D.M, Le, T.B.K.
Deposit date:2019-07-03
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Diversification of DNA-Binding Specificity by Permissive and Specificity-Switching Mutations in the ParB/Noc Protein Family.
Cell Rep, 32, 2020
5CM2
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Structure of Y. lipolytica Trm9-Trm112 complex, a methyltransferase modifying U34 in the anticodon loop of some tRNAs
Descriptor: TRNA METHYLTRANSFERASE, TRNA METHYLTRANSFERASE ACTIVATOR SUBUNIT, ZINC ION
Authors:Letoquart, J, van Tran, N, Caroline, V, Aleksandrov, A, Lazar, N, Van Tilbeurgh, H, Liger, D, Graille, M.
Deposit date:2015-07-16
Release date:2015-10-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure.
Nucleic Acids Res., 43, 2015
8SBR
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E coli. CTP synthase in complex with CTP (sodium malonate + 20 mM MgCl2)
Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MALONIC ACID
Authors:Holyoak, T, McLeod, M.J, Tran, N.
Deposit date:2023-04-04
Release date:2023-05-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
4PM4
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BU of 4pm4 by Molmil
Structure of a putative periplasmic iron siderophore binding protein (Rv0265c) from Mycobacterium tuberculosis H37Rv
Descriptor: CHLORIDE ION, Iron complex transporter substrate-binding protein, SULFATE ION
Authors:Arbing, M.A, Chan, S, Tran, N, Kuo, E, Lu, J, Harris, L.R, Zhou, T.T, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2014-05-20
Release date:2014-06-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a putative periplasmic iron siderophore binding protein (Rv0265c) from Mycobacterium tuberculosis H37Rv
To Be Published
6Q8J
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Nterminal domain of human SMU1 in complex with LSP641
Descriptor: 1-~{tert}-butyl-3-[6-(3,5-dimethoxyphenyl)-2-[[1-[1-(phenylmethyl)piperidin-4-yl]-1,2,3-triazol-4-yl]methylamino]pyrido[2,3-d]pyrimidin-7-yl]urea, WD40 repeat-containing protein SMU1
Authors:Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Q8I
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Nterminal domain of human SMU1 in complex with human REDmid
Descriptor: Protein Red, WD40 repeat-containing protein SMU1
Authors:Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
6FQB
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MurT/GatD peptidoglycan amidotransferase complex from Streptococcus pneumoniae R6
Descriptor: Cobyric acid synthase, GLUTAMINE, Mur ligase family protein
Authors:Morlot, C, Contreras-Martel, C, Leisico, F, Straume, D, Peters, K, Hegnar, O.A, Simon, N, Villard, A.M, Breukink, E, Gravier-Pelletier, C, Le Corre, L, Vollmer, W, Pietrancosta, N, Havarstein, L.S, Zapun, A.
Deposit date:2018-02-13
Release date:2018-08-22
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae.
Nat Commun, 9, 2018
6Q8F
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Nterminal domain of human SMU1
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, WD40 repeat-containing protein SMU1
Authors:Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
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