1JGT
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![BU of 1jgt by Molmil](/molmil-images/mine/1jgt) | CRYSTAL STRUCTURE OF BETA-LACTAM SYNTHETASE | Descriptor: | BETA-LACTAM SYNTHETASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GLYCEROL, ... | Authors: | Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2001-06-26 | Release date: | 2001-12-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of beta-lactam synthetase reveals how to synthesize antibiotics instead of asparagine. Nat.Struct.Biol., 8, 2001
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6FIJ
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![BU of 6fij by Molmil](/molmil-images/mine/6fij) | Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ... | Authors: | Herbst, D.A, Jakob, R.P, Townsend, C.A, Maier, T. | Deposit date: | 2018-01-18 | Release date: | 2018-03-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | The structural organization of substrate loading in iterative polyketide synthases. Nat. Chem. Biol., 14, 2018
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6FIK
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![BU of 6fik by Molmil](/molmil-images/mine/6fik) | ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS | Descriptor: | Polyketide synthase | Authors: | Herbst, D.A, Huitt-Roehl, C.R, Jakob, R.P, Townsend, C.A, Maier, T. | Deposit date: | 2018-01-18 | Release date: | 2018-03-21 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | The structural organization of substrate loading in iterative polyketide synthases. Nat. Chem. Biol., 14, 2018
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5MPT
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![BU of 5mpt by Molmil](/molmil-images/mine/5mpt) | Structure of the citrinin polyketide synthase CMeT domain | Descriptor: | 1,2-ETHANEDIOL, Citrinin polyketide synthase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Herbst, D.A, Storm, P.A, Townsend, C.A, Maier, T. | Deposit date: | 2016-12-19 | Release date: | 2017-02-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.648 Å) | Cite: | Functional and Structural Analysis of Programmed C-Methylation in the Biosynthesis of the Fungal Polyketide Citrinin. Cell Chem Biol, 24, 2017
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5KBZ
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![BU of 5kbz by Molmil](/molmil-images/mine/5kbz) | Structure of the PksA Product Template domain in complex with a phosphopantetheine mimetic | Descriptor: | (14R)-14-hydroxy-15,15-dimethyl-1-[5-({[(5-methyl-1,2-oxazol-3-yl)methyl]sulfanyl}methyl)-1,2-oxazol-3-yl]-4,9,13-trioxo-2-thia-5,8,12-triazahexadecan-16-yl dihydrogen phosphate, Noranthrone synthase | Authors: | Tsai, S.C, Burkart, M.D, Townsend, C.A, Barajas, J.F, Shakya, G, Topper, C.L, Moreno, G, Jackson, D.R, Rivera, H, La Clair, J.J, Vagstad, A. | Deposit date: | 2016-06-03 | Release date: | 2017-05-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1Q19
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![BU of 1q19 by Molmil](/molmil-images/mine/1q19) | Carbapenam Synthetase | Descriptor: | (2S,5S)-5-CARBOXYMETHYLPROLINE, CarA, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | Authors: | Miller, M.T, Gerratana, B, Stapon, A, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2003-07-18 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Carbapenam Synthetase (CarA) J.Biol.Chem., 278, 2003
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1Q15
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![BU of 1q15 by Molmil](/molmil-images/mine/1q15) | Carbapenam Synthetase | Descriptor: | CarA | Authors: | Miller, M.T, Gerratana, B, Stapon, A, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2003-07-18 | Release date: | 2003-11-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Carbapenam Synthetase (CarA) J.Biol.Chem., 278, 2003
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4IHD
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![BU of 4ihd by Molmil](/molmil-images/mine/4ihd) | |
4IHE
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![BU of 4ihe by Molmil](/molmil-images/mine/4ihe) | |
1MBZ
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![BU of 1mbz by Molmil](/molmil-images/mine/1mbz) | BETA-LACTAM SYNTHETASE WITH TRAPPED INTERMEDIATE | Descriptor: | ARGININE-N-METHYLCARBONYL PHOSPHORIC ACID 5'-ADENOSINE ESTER, BETA-LACTAM SYNTHETASE, GLYCEROL, ... | Authors: | Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2002-08-04 | Release date: | 2002-10-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots Proc.Natl.Acad.Sci.USA, 99, 2002
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1M1Z
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![BU of 1m1z by Molmil](/molmil-images/mine/1m1z) | |
1MB9
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![BU of 1mb9 by Molmil](/molmil-images/mine/1mb9) | BETA-LACTAM SYNTHETASE COMPLEXED WITH ATP | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, BETA-LACTAM SYNTHETASE, ... | Authors: | Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2002-08-02 | Release date: | 2002-10-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots Proc.Natl.Acad.Sci.USA, 99, 2002
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1MC1
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![BU of 1mc1 by Molmil](/molmil-images/mine/1mc1) | BETA-LACTAM SYNTHETASE WITH PRODUCT (DGPC), AMP AND PPI | Descriptor: | ADENOSINE MONOPHOSPHATE, BETA-LACTAM SYNTHETASE, DEOXYGUANIDINOPROCLAVAMINIC ACID, ... | Authors: | Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2002-08-04 | Release date: | 2002-10-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots Proc.Natl.Acad.Sci.USA, 99, 2002
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