6Z7O
| Crystal structure of Thioredoxin T from Drosophila melanogaster | Descriptor: | Thioredoxin-T, ZINC ION | Authors: | Freier, R, Aragon, E, Baginski, B, Pluta, R, Martin-Malpartida, P, Torner, C, Gonzaez, C, Macias, M. | Deposit date: | 2020-05-31 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins. Iucrj, 8, 2021
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5LMX
| Monomeric RNA polymerase I at 4.9 A resolution | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Torreira, E, Louro, J.A, Gil-Carton, D, Gallego, O, Calvo, O, Fernandez-Tornero, C. | Deposit date: | 2016-08-02 | Release date: | 2017-03-22 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription. Elife, 6, 2017
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6TUS
| human XPG, Apo2 form | Descriptor: | DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells, GLYCEROL, SULFATE ION | Authors: | Ruiz, F.M, Fernandez-Tornero, C. | Deposit date: | 2020-01-08 | Release date: | 2020-09-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair. Nucleic Acids Res., 48, 2020
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8BWS
| Structure of yeast RNA Polymerase III elongation complex at 3.3 A | Descriptor: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | Authors: | Nguyen, P.Q, Fernandez-Tornero, C. | Deposit date: | 2022-12-07 | Release date: | 2023-04-05 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration. Nat Commun, 14, 2023
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3NSU
| A Systematic Screen for Protein-Lipid Interactions in Saccharomyces cerevisiae | Descriptor: | Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1, SULFATE ION | Authors: | Gallego, O, Fernandez-Tornero, C, Aguilar-Gurrieri, C, Muller, C, Gavin, A.C. | Deposit date: | 2010-07-02 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. Mol. Syst. Biol., 6, 2010
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8RTH
| Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase | Descriptor: | 3-methylcrotonyl-CoA carboxylase, putative, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ... | Authors: | Ruiz, F.M, Plaza-Pegueroles, A, Fernandez-Tornero, C. | Deposit date: | 2024-01-26 | Release date: | 2024-04-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.37 Å) | Cite: | The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function. Structure, 32, 2024
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2J04
| The tau60-tau91 subcomplex of yeast transcription factor IIIC | Descriptor: | HYPOTHETICAL PROTEIN YPL007C, YDR362CP | Authors: | Mylona, A, Fernandez-Tornero, C, Legrand, P, Muller, C.W. | Deposit date: | 2006-07-31 | Release date: | 2006-10-23 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of the Tau60/Deltatau91 Subcomplex of Yeast Transcription Factor Iiic: Insights Into Preinitiation Complex Assembly Mol.Cell, 24, 2006
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1HKN
| A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate | Descriptor: | 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1 | Authors: | Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A. | Deposit date: | 2003-03-10 | Release date: | 2004-03-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate J.Biol.Chem., 278, 2003
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1HKQ
| PPS10 plasmid DNA replication initiator protein RepA. Replication inactive, dimeric N-terminal domain. | Descriptor: | BENZOIC ACID, MERCURY (II) ION, PHOSPHATE ION, ... | Authors: | Giraldo, R, Fernandez-Tornero, C, Evans, P.R, Diaz-Orejas, R, Romero, A. | Deposit date: | 2003-03-11 | Release date: | 2003-05-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A Conformational Switch between Transcriptional Repression and Replication Initiation in Repa Dimerization Domain Nat.Struct.Biol., 10, 2003
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7Z31
| Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore). | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C. | Deposit date: | 2022-03-01 | Release date: | 2023-04-05 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration. Nat Commun, 14, 2023
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7Z0H
| Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40). | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C. | Deposit date: | 2022-02-22 | Release date: | 2023-04-05 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration. Nat Commun, 14, 2023
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6YD1
| SaFtsZ-DFMBA | Descriptor: | 2,6-difluoro-3-methoxybenzamide, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | Deposit date: | 2020-03-20 | Release date: | 2021-07-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery. J.Med.Chem., 64, 2021
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6YD6
| SaFtsZ-UCM152 (comp.20) | Descriptor: | 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, 2,6-bis(fluoranyl)-3-[[3-(trifluoromethyl)phenyl]methoxy]benzamide, ... | Authors: | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | Deposit date: | 2020-03-20 | Release date: | 2021-07-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery. J.Med.Chem., 64, 2021
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6YD5
| SaFtsZ-UCM151 (comp. 18) | Descriptor: | 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, 3-[(3-chlorophenyl)methoxy]-2,6-bis(fluoranyl)benzamide, ... | Authors: | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | Deposit date: | 2020-03-20 | Release date: | 2021-07-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery. J.Med.Chem., 64, 2021
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7Z30
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7Z2Z
| Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A | Descriptor: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | Authors: | Nguyen, P.Q, Fernandez-Tornero, C. | Deposit date: | 2022-03-01 | Release date: | 2023-04-05 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration. Nat Commun, 14, 2023
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2BYM
| Histone fold heterodimer of the Chromatin Accessibility Complex | Descriptor: | CADMIUM ION, CHRAC-14, CHRAC-16 | Authors: | Fernandez-Tornero, C, Hartlepp, K.F, Grune, T, Eberharter, A, Becker, P.B, Muller, C.W. | Deposit date: | 2005-08-03 | Release date: | 2005-11-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Histone Fold Subunits of Drosophila Chrac Facilitate Nucleosome Sliding Through Dynamic DNA Interactions. Mol.Cell.Biol., 25, 2005
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2BML
| Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AUTOLYSIN, DEXTROFLOXACINE, ... | Authors: | Fernandez-Tornero, C, Gimenez-Gallego, G, Romero, A, Garcia, E, Pascual-Teresa, B.D, Lopez, R. | Deposit date: | 2005-03-15 | Release date: | 2005-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Ofloxacin-Like Antibiotics Inhibit Pneumococcal Cell Wall-Degrading Virulence Factors J.Biol.Chem., 280, 2005
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2BYK
| Histone fold heterodimer of the Chromatin Accessibility Complex | Descriptor: | CHRAC-14, CHRAC-16, SULFATE ION | Authors: | Fernandez-Tornero, C, Hartlepp, K.F, Grune, T, Eberharter, A, Becker, P.B, Muller, C.W. | Deposit date: | 2005-08-03 | Release date: | 2005-11-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Histone Fold Subunits of Drosophila Chrac Facilitate Nucleosome Sliding Through Dynamic DNA Interactions. Mol.Cell.Biol., 25, 2005
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2YN0
| tau55 histidine phosphatase domain | Descriptor: | PHOSPHATE ION, TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT | Authors: | Taylor, N.M.I, Glatt, S, Hennrich, M, von Scheven, G, Grotsch, H, Fernandez-Tornero, C, Rybin, V, Gavin, A.C, Kolb, P, Muller, C.W. | Deposit date: | 2012-10-11 | Release date: | 2013-04-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor Iiic. J.Biol.Chem., 288, 2013
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7ON3
| SaFtsZ complexed with GDP (soak 10 mM EGTA) | Descriptor: | 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | Deposit date: | 2021-05-25 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics. Plos Biol., 20, 2022
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7OJD
| SaFtsZ(D46A) complexed with GDP | Descriptor: | 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | Deposit date: | 2021-05-14 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics. Plos Biol., 20, 2022
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7OMP
| SaFtsZ complexed with GDPPCP and Mg2+ | Descriptor: | 1,2-ETHANEDIOL, Cell division protein FtsZ, MAGNESIUM ION, ... | Authors: | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | Deposit date: | 2021-05-24 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics. Plos Biol., 20, 2022
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7OJA
| SaFtsZ(D210N) complexed with GDP | Descriptor: | 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | Deposit date: | 2021-05-14 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics. Plos Biol., 20, 2022
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7ON4
| SaFtsZ complexed with GDP (co-crystalization with 1mM EDTA) | Descriptor: | 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | Deposit date: | 2021-05-25 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics. Plos Biol., 20, 2022
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