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PDB: 15 results
3ZV2
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BU of 3zv2 by Molmil
Human protein-tyrosine phosphatase 1b C215A, S216A mutant
Descriptor: Tyrosine-protein phosphatase non-receptor type 1
Authors:Barford, D, Salmeen, A, Tonks, N.K.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity.
Cell, 147, 2011
1RPM
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BU of 1rpm by Molmil
HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE MU, DOMAIN 1
Descriptor: RECEPTOR PROTEIN TYROSINE PHOSPHATASE MU
Authors:Hoffmann, K.M.V, Tonks, N.K, Barford, D.
Deposit date:1997-09-11
Release date:1998-04-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of domain 1 of receptor protein-tyrosine phosphatase mu.
J.Biol.Chem., 272, 1997
5VF6
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BU of 5vf6 by Molmil
Crystal structure of single chain variable fragment (scFv45).
Descriptor: single chain variable fragment
Authors:Shrestha, O.K, Tocilj, A, Joshua-Tor, L, Tonks, N.K.
Deposit date:2017-04-06
Release date:2018-01-31
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.635 Å)
Cite:Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development.
Nat Commun, 9, 2018
2HNQ
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CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE 1B
Descriptor: PROTEIN-TYROSINE PHOSPHATASE-1B, TUNGSTATE(VI)ION
Authors:Barford, D, Flint, A.J, Tonks, N.K.
Deposit date:1994-09-28
Release date:1994-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of human protein tyrosine phosphatase 1B.
Science, 263, 1994
2HNP
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BU of 2hnp by Molmil
CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE 1B
Descriptor: PROTEIN-TYROSINE PHOSPHATASE-1B
Authors:Barford, D, Flint, A.J, Tonks, N.K.
Deposit date:1994-09-19
Release date:1994-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of human protein tyrosine phosphatase 1B.
Science, 263, 1994
1A5Y
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BU of 1a5y by Molmil
PROTEIN TYROSINE PHOSPHATASE 1B CYSTEINYL-PHOSPHATE INTERMEDIATE
Descriptor: PROTEIN TYROSINE PHOSPHATASE 1B
Authors:Pannifer, A.D.P, Flint, A.J, Tonks, N.K, Barford, D.
Deposit date:1998-02-19
Release date:1998-06-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by x-ray crystallography.
J.Biol.Chem., 273, 1998
1G1G
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BU of 1g1g by Molmil
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A MONO-PHOSPHORYLATED PEPTIDE (ETDY(PTR)RKGGKGLL) FROM THE INSULIN RECEPTOR KINASE
Descriptor: MONO-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE, PROTEIN TYROSINE PHOSPHATASE 1B
Authors:Salmeen, A, Andersen, J.N, Myers, M.P, Tonks, N.K, Barford, D.
Deposit date:2000-10-11
Release date:2001-01-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
Mol.Cell, 6, 2000
1G1F
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BU of 1g1f by Molmil
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A TRI-PHOSPHORYLATED PEPTIDE (RDI(PTR)ETD(PTR)(PTR)RK) FROM THE INSULIN RECEPTOR KINASE
Descriptor: PROTEIN TYROSINE PHOSPHATASE 1B, TRI-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE
Authors:Salmeen, A, Andersen, J.N, Myers, M.P, Tonks, N.K, Barford, D.
Deposit date:2000-10-11
Release date:2001-01-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
Mol.Cell, 6, 2000
1G1H
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BU of 1g1h by Molmil
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A BIS-PHOSPHORYLATED PEPTIDE (ETD(PTR)(PTR)RKGGKGLL) FROM THE INSULIN RECEPTOR KINASE
Descriptor: BI-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE, PROTEIN TYROSINE PHOSPHATASE 1B
Authors:Salmeen, A, Andersen, J.N, Myers, M.P, Tonks, N.K, Barford, D.
Deposit date:2000-10-11
Release date:2001-01-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
Mol.Cell, 6, 2000
1H6G
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BU of 1h6g by Molmil
alpha-catenin M-domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-1 CATENIN, CALCIUM ION, ...
Authors:Yang, J, Dokurno, P, Tonks, N.K, Barford, D.
Deposit date:2001-06-14
Release date:2001-08-07
Last modified:2016-02-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion.
Embo J., 20, 2001
1OEO
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BU of 1oeo by Molmil
PTP1B with the catalytic cysteine oxidized to sulfonic acid
Descriptor: PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
Authors:Salmeen, A, Andersen, J.N, Myers, M.P, Meng, T.C, Hinks, J.A, Tonks, N.K, Barford, D.
Deposit date:2003-03-28
Release date:2003-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Redox Regulation of Protein Tyrosine Phosphatase Involves a Sulfenyl-Amide Intermediate
Nature, 423, 2003
1OEM
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PTP1B with the catalytic cysteine oxidized to a sulfenyl-amide bond
Descriptor: PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
Authors:Salmeen, A, Andersen, J.N, Myers, M.P, Meng, T.C, Hinks, J.A, Tonks, N.K, Barford, D.
Deposit date:2003-03-28
Release date:2003-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Redox Regulation of Protein Tyrosine Phosphatase Involves a Sulfenyl-Amide Intermediate
Nature, 423, 2003
1OHD
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BU of 1ohd by Molmil
structure of cdc14 in complex with tungstate
Descriptor: CDC14B2 PHOSPHATASE, TUNGSTATE(VI)ION
Authors:Gray, C.H, Good, V.M, Tonks, N.K, Barford, D.
Deposit date:2003-05-24
Release date:2003-07-24
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Embo J., 22, 2003
1OHC
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BU of 1ohc by Molmil
Structure of the proline directed phosphatase cdc14
Descriptor: CDC14B2 PHOSPHATASE
Authors:Gray, C.H, Good, V.M, Tonks, N.K, Barford, D.
Deposit date:2003-05-24
Release date:2003-07-24
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Embo J., 22, 2003
1OHE
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BU of 1ohe by Molmil
Structure of cdc14b phosphatase with a peptide ligand
Descriptor: CDC14B2 PHOSPHATASE, PEPTIDE LIGAND
Authors:Gray, C.H, Good, V.M, Tonks, N.K, Barford, D.
Deposit date:2003-05-24
Release date:2003-07-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Embo J., 22, 2003

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