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PDB: 22 件

5JWY
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BU of 5jwy by Molmil
Structure of lipid phosphate phosphatase PgpB complex with PE
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Phosphatidylglycerophosphatase B
著者Tong, S, Wang, M, Zheng, L.
登録日2016-05-12
公開日2016-07-20
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane.
J.Biol.Chem., 291, 2016
6K1S
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BU of 6k1s by Molmil
Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase (PRMT5) Inhibitors
分子名称: 1,2-ETHANEDIOL, 2-[[7-[(2~{R},3~{R},4~{S},5~{R})-5-[(~{R})-(4-chlorophenyl)-oxidanyl-methyl]-3,4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidin-4-yl]amino]ethanal, DIMETHYL SULFOXIDE, ...
著者Tong, S, Lin, H.
登録日2019-05-12
公開日2019-06-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors.
Acs Med.Chem.Lett., 10, 2019
3EHR
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BU of 3ehr by Molmil
Crystal Structure of Human Osteoclast Stimulating Factor
分子名称: Osteoclast-stimulating factor 1
著者Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L.
登録日2008-09-14
公開日2009-08-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
3EHQ
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BU of 3ehq by Molmil
Crystal Structure of Human Osteoclast Stimulating Factor
分子名称: 1,2-ETHANEDIOL, Osteoclast-stimulating factor 1
著者Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L.
登録日2008-09-14
公開日2009-08-04
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
6ECK
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BU of 6eck by Molmil
Pyruvate Kinase Isoform L-type with phosphorylated Ser113 (pS113) in complex with FBP
分子名称: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, CITRATE ANION, ...
著者Padyana, A, Tong, S.
登録日2018-08-08
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production.
Cell Rep, 29, 2019
6ECH
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BU of 6ech by Molmil
Pyruvate Kinase Isoform L-type with phosphorylated Ser12 (pS12) in complex with FBP
分子名称: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Padyana, A, Tong, S.
登録日2018-08-07
公開日2019-12-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production.
Cell Rep, 29, 2019
4JLL
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BU of 4jll by Molmil
Crystal Structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1 covalently bound with FP-alkyne, Northeast Structural Genomics Consortium (NESG) Target OR273
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Tong, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2013-03-12
公開日2013-04-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
4JVV
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BU of 4jvv by Molmil
Crystal structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1, covalently bound with diisopropyl fluorophosphate (DFP), Northeast Structural Genomics Consortium (NESG) Target OR273
分子名称: evolved variant of the computationally designed serine hydrolase
著者Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Tong, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2013-03-26
公開日2013-04-24
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.288 Å)
主引用文献Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
4JCA
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BU of 4jca by Molmil
Crystal Structure of the apo form of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1. Northeast Structural Genomics Consortium (NESG) Target OR273
分子名称: CITRIC ACID, RUBIDIUM ION, serine hydrolase
著者Kuzin, A.P, Lew, S, Rajagopalan, S, Seetharaman, J, Tong, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2013-02-21
公開日2013-03-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
3B4D
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BU of 3b4d by Molmil
Crystal Structure of Human PABPN1 RRM
分子名称: Polyadenylate-binding protein 2
著者Ge, H, Tong, S, Teng, M, Niu, L.
登録日2007-10-24
公開日2008-01-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal structure and possible dimerization of the single RRM of human PABPN1
Proteins, 71, 2008
4KJS
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BU of 4kjs by Molmil
Structure of native YfkE
分子名称: cation exchanger YfkE
著者Wu, M, Tong, S, Zheng, L.
登録日2013-05-03
公開日2013-06-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KJR
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BU of 4kjr by Molmil
Crystal structure of selenium substituted Ca2+/H+ antiporter proteinYfkE
分子名称: cation exchanger YfkE
著者Wu, M, Tong, S, Zheng, L.
登録日2013-05-03
公開日2013-07-03
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation.
Proc.Natl.Acad.Sci.USA, 110, 2013
2KZ5
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BU of 2kz5 by Molmil
Solution NMR Structure of Transcription factor NF-E2 subunit's DNA binding domain from Homo sapiens, Northeast Structural Genomics Consortium Target HR4653B
分子名称: Transcription factor NF-E2 45 kDa subunit
著者Liu, G, Janjua, H, Xiao, R, Ciccosanti, C, Shastry, R, Acton, T.B, Tong, S, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2010-06-11
公開日2010-07-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Northeast Structural Genomics Consortium Target HR4653B
To be Published
3ELI
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BU of 3eli by Molmil
Crystal structure of the AHSA1 (SPO3351) protein from Silicibacter pomeroyi, Northeast Structural Genomics Consortium Target SiR160
分子名称: Aha1 domain protein
著者Forouhar, F, Su, M, Seetharaman, J, Janjua, H, Xiao, R, Ciccosanti, C, Foote, E.L, Wang, D, Tong, S, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2008-09-22
公開日2008-09-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the AHSA1 (SPO3351) protein from Silicibacter pomeroyi, Northeast Structural Genomics Consortium Target SiR160
To be Published
3E23
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BU of 3e23 by Molmil
Crystal structure of the RPA2492 protein in complex with SAM from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR299
分子名称: S-ADENOSYLMETHIONINE, SULFATE ION, uncharacterized protein RPA2492
著者Forouhar, F, Chen, Y, Seetharaman, J, Mao, L, Xiao, R, Foote, E.L, Ciccosanti, C, Wang, H, Tong, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2008-08-05
公開日2008-09-30
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the RPA2492 protein in complex with SAM from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR299
To be Published
3DTO
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BU of 3dto by Molmil
Crystal structure of the metal-dependent HD domain-containing hydrolase BH2835 from Bacillus halodurans, Northeast Structural Genomics Consortium Target BhR130.
分子名称: BH2835 protein
著者Forouhar, F, Su, M, Seetharaman, J, Janjua, H, Fang, Y, Xiao, R, Cunningham, K, Ma, L.-C, Owen, L.A, Wang, D, Tong, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2008-07-15
公開日2008-09-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of the metal-dependent HD domain-containing hydrolase BH2835 from Bacillus halodurans, Northeast Structural Genomics Consortium Target BhR130.
To be Published
3P6Y
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BU of 3p6y by Molmil
CF Im25-CF Im68-UGUAA complex
分子名称: 5'-R(*UP*GP*UP*AP*A)-3', Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6
著者Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M.
登録日2010-10-11
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
3P5T
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BU of 3p5t by Molmil
CFIm25-CFIm68 complex
分子名称: Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6
著者Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M.
登録日2010-10-11
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
2L0B
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BU of 2l0b by Molmil
Solution NMR structure of zinc finger domain of E3 ubiquitin-protein ligase praja-1 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) target HR4710B
分子名称: E3 ubiquitin-protein ligase Praja-1, ZINC ION
著者Liu, G, Tong, S, Hamilton, K, Ciccosanti, C, Shastry, R, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2010-06-30
公開日2010-08-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of zinc finger domain of E3 ubiquitin-protein ligase protein praja-1 from Homo sapiens, northeast structural genomics consortium (NESG) target HR4710B
To be Published
2L81
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BU of 2l81 by Molmil
Solution NMR Structure of the serine-rich domain of hEF1 (Enhancer of filamentation 1) from Homo sapiens, Northeast Structural Genomics Consortium Target HR5554A
分子名称: Enhancer of filamentation 1
著者Liu, G, Xiao, R, Huang, Y.J, Patel, D, Ciccosanti, C.T, Acton, T.B, Tong, S, Everett, J.T, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2010-12-31
公開日2011-02-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Northeast Structural Genomics Consortium Target HR5554A
To be Published
2L82
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BU of 2l82 by Molmil
Solution NMR Structure of de novo designed protein, P-loop NTPase fold, Northeast Structural Genomics Consortium Target OR32
分子名称: DESIGNED PROTEIN OR32
著者Liu, G, Koga, N, Koga, R, Xiao, R, Hamilton, K, Janjua, H, Tong, S, Acton, T.B, Everett, J, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2010-12-31
公開日2011-02-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Northeast Structural Genomics Consortium Target OR32
To be Published
3E48
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BU of 3e48 by Molmil
Crystal structure of a nucleoside-diphosphate-sugar epimerase (SAV0421) from Staphylococcus aureus, Northeast Structural Genomics Consortium Target ZR319
分子名称: MAGNESIUM ION, Putative nucleoside-diphosphate-sugar epimerase
著者Forouhar, F, Abashidze, M, Seetharaman, J, Mao, L, Janjua, H, Xiao, R, Ciccosanti, C, Foote, E.L, Wang, D, Tong, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2008-08-11
公開日2008-08-19
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献

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