6ECH
Pyruvate Kinase Isoform L-type with phosphorylated Ser12 (pS12) in complex with FBP
Summary for 6ECH
Entry DOI | 10.2210/pdb6ech/pdb |
Related | 6ECK |
Descriptor | Pyruvate kinase PKLR, CHLORIDE ION, 1,6-di-O-phosphono-beta-D-fructofuranose, ... (11 entities in total) |
Functional Keywords | pkl, pyruvate kinase, glycolysis, transferase |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 245832.23 |
Authors | Padyana, A.,Tong, S. (deposition date: 2018-08-07, release date: 2019-12-04, Last modification date: 2024-10-09) |
Primary citation | Gassaway, B.M.,Cardone, R.L.,Padyana, A.K.,Petersen, M.C.,Judd, E.T.,Hayes, S.,Tong, S.,Barber, K.W.,Apostolidi, M.,Abulizi, A.,Sheetz, J.B.,Aerni, H.R.,Gross, S.,Kung, C.,Samuel, V.T.,Shulman, G.I.,Kibbey, R.G.,Rinehart, J. Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Rep, 29:3394-3404.e9, 2019 Cited by PubMed: 31825824DOI: 10.1016/j.celrep.2019.11.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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