6ECH
Pyruvate Kinase Isoform L-type with phosphorylated Ser12 (pS12) in complex with FBP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase PKLR | polymer | 550 | 59910.5 | 4 | UniProt (P12928) Pfam (PF00224) Pfam (PF02887) | Rattus norvegicus (Rat) | L-PK,Pyruvate kinase isozymes L/R |
| 2 | E, LA, U, YA (A, C, B, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) | |||
| 3 | AB, BB, F, G, H... (D, A, C, B) | MAGNESIUM ION | non-polymer | 24.3 | 13 | Chemie (MG) | |||
| 4 | CB, J, Z (D, A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
| 5 | AA, DB, K, OA (B, D, A, C) | OXALATE ION | non-polymer | 88.0 | 4 | Chemie (OXL) | |||
| 6 | CA, DA, EA, EB, FA... (B, D, A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 33 | Chemie (EDO) | |||
| 7 | MB, S (D, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 8 | T (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 9 | BA (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 10 | NB (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 11 | OB, PB, QB, RB (A, B, C, D) | water | water | 18.0 | 1201 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 543 (UniProt: P12928)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
| His 544 | - | expression tag |
| His 545 | - | expression tag |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 239641.8 | |
| Non-Polymers* | Number of molecules | 62 |
| Total formula weight | 6190.4 | |
| All* | Total formula weight | 245832.2 |
