8FDT
| Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-04 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FDU
| Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi (local refined on AAA3-AAA5 and LIS1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, Platelet-activating factor acetylhydrolase IB subunit beta,Platelet-activating factor acetylhydrolase IB subunit beta,human LIS1 protein with a SNAP tag | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-04 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FCY
| Engineered human dynein motor domain in microtubule-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-01 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FD6
| Engineered human dynein motor domain in the microtubule-unbound state in the buffer containing ATP-Vi | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-02 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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5I7J
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5I7K
| Crystal Structure of Human SPLUNC1 Dolphin Mutant D1 (G58A, S61A, G62E, G63D, G66D, I67T) | 分子名称: | BPI fold-containing family A member 1 | 著者 | Walton, W.G, Redinbo, M.R. | 登録日 | 2016-02-17 | 公開日 | 2016-05-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.552 Å) | 主引用文献 | Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1. Biochemistry, 55, 2016
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5I7L
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1IIN
| thymidylyltransferase complexed with UDP-glucose | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, glucose-1-phosphate thymidylyltransferase | 著者 | Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B. | 登録日 | 2001-04-23 | 公開日 | 2001-05-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nat.Struct.Biol., 8, 2001
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1IIM
| thymidylyltransferase complexed with TTP | 分子名称: | THYMIDINE-5'-TRIPHOSPHATE, glucose-1-phosphate thymidylyltransferase | 著者 | Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B. | 登録日 | 2001-04-23 | 公開日 | 2001-05-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nat.Struct.Biol., 8, 2001
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6NCX
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6P2B
| Tethered PXR-LBD/SRC-1p bound to Garcinoic Acid | 分子名称: | (2Z,6E,10E)-13-[(2R)-6-hydroxy-2,8-dimethyl-3,4-dihydro-2H-1-benzopyran-2-yl]-2,6,10-trimethyltrideca-2,6,10-trienoic acid, DIMETHYL SULFOXIDE, Nuclear receptor subfamily 1 group I member 2 | 著者 | Walton, W.G, Pellock, S.J, Redinbo, M.R. | 登録日 | 2019-05-21 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor. J.Med.Chem., 63, 2020
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6D89
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6D1N
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5UJ6
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6D1P
| Apo structure of Bacteroides uniformis beta-glucuronidase 3 | 分子名称: | GLYCEROL, Glycosyl hydrolases family 2, sugar binding domain protein, ... | 著者 | Walton, W.G, Pellock, S.J, Redinbo, M.R. | 登録日 | 2018-04-12 | 公開日 | 2018-10-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
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6D41
| Bacteriodes uniformis beta-glucuronidase 1 bound to D-glucaro-1,5-lactone | 分子名称: | (2S,3S,4S,5R)-3,4,5-trihydroxy-6-oxo-oxane-2-carboxylic acid, Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, ... | 著者 | Walton, W.G, Pellock, S.J, Redinbo, M.R. | 登録日 | 2018-04-17 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
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6D50
| Bacteroides uniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone | 分子名称: | (2S,3S,4S,5R)-3,4,5-trihydroxy-6-oxo-oxane-2-carboxylic acid, CALCIUM ION, Glycosyl hydrolases family 2, ... | 著者 | Walton, W.G, Pellock, S.J, Redinbo, M.R. | 登録日 | 2018-04-19 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
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6NCZ
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6NCY
| Crystal structure of hybrid beta-glucuronidase/beta-galacturonidase from Fusicatenibacter saccharivorans | 分子名称: | Beta-glucuronidase, GLYCEROL, NICKEL (II) ION, ... | 著者 | Walton, W.G, Pellock, S.J, Redinbo, M.R. | 登録日 | 2018-12-12 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome. Biochemistry, 58, 2019
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6D7F
| Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide | 分子名称: | Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL, ... | 著者 | Walton, W.G, Pellock, S.J, Redinbo, M.R. | 登録日 | 2018-04-24 | 公開日 | 2018-10-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
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6D6W
| Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate | 分子名称: | Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL, ... | 著者 | Walton, W.G, Pellock, S.J, Redinbo, M.R. | 登録日 | 2018-04-23 | 公開日 | 2018-10-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
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8DTQ
| Crystal Structure of Staphylococcus aureus pSK41 Cop | 分子名称: | CHLORIDE ION, Helix-turn-helix domain, SODIUM ION | 著者 | Walton, W.G, Eakes, T.C, Redinbo, M.R, McLaughlin, K.J. | 登録日 | 2022-07-26 | 公開日 | 2023-08-02 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | pSK41/pGO1-family conjugative plasmids of Staphylococcus aureus encode a cryptic repressor of replication. Plasmid, 128, 2023
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6NCW
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6D8K
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5GTT
| Crystal structure of C. perfringens iota-like enterotoxin CPILE-a | 分子名称: | 1,2-ETHANEDIOL, Binary enterotoxin of Clostridium perfringens component a | 著者 | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | 登録日 | 2016-08-23 | 公開日 | 2017-03-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.011 Å) | 主引用文献 | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin PLoS ONE, 12, 2017
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