8ER1
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![BU of 8er1 by Molmil](/molmil-images/mine/8er1) | X-ray crystal structure of Tet(X6) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase | Authors: | Kumar, H, Tolia, N.H. | Deposit date: | 2022-10-11 | Release date: | 2023-04-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Commun Biol, 6, 2023
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8ER0
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![BU of 8er0 by Molmil](/molmil-images/mine/8er0) | X-ray crystal structure of Tet(X6) bound to anhydrotetracycline | Descriptor: | 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase | Authors: | Kumar, H, Tolia, N.H. | Deposit date: | 2022-10-11 | Release date: | 2023-04-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Commun Biol, 6, 2023
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1R6Z
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![BU of 1r6z by Molmil](/molmil-images/mine/1r6z) | The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion) | Descriptor: | Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L. | Deposit date: | 2003-10-17 | Release date: | 2004-01-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat.Struct.Biol., 10, 2003
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8DCE
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![BU of 8dce by Molmil](/molmil-images/mine/8dce) | |
8DFH
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![BU of 8dfh by Molmil](/molmil-images/mine/8dfh) | |
8DFI
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![BU of 8dfi by Molmil](/molmil-images/mine/8dfi) | |
8DFG
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![BU of 8dfg by Molmil](/molmil-images/mine/8dfg) | |
6O38
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![BU of 6o38 by Molmil](/molmil-images/mine/6o38) | Structure of a chaperone-substrate complex | Descriptor: | Acinetobacter secreted protease CpaA, SULFATE ION, Type II secretion chaperone CpaB, ... | Authors: | Urusova, D.V, Tolia, N.H. | Deposit date: | 2019-02-26 | Release date: | 2019-07-24 | Last modified: | 2019-09-25 | Method: | X-RAY DIFFRACTION (2.595 Å) | Cite: | The structure ofAcinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone-substrate interaction. J.Biol.Chem., 294, 2019
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6OAN
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![BU of 6oan by Molmil](/molmil-images/mine/6oan) | Structure of DBP in complex with human neutralizing antibody 053054 | Descriptor: | Antibody 053054 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION | Authors: | Urusova, D, Tolia, N.H. | Deposit date: | 2019-03-18 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP. Nat Microbiol, 4, 2019
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6OAO
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![BU of 6oao by Molmil](/molmil-images/mine/6oao) | Structure of DBP in complex with human neutralizing antibody 092096 | Descriptor: | Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION | Authors: | Urusova, D, Tolia, N.H. | Deposit date: | 2019-03-18 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.497 Å) | Cite: | Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP. Nat Microbiol, 4, 2019
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4QEX
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![BU of 4qex by Molmil](/molmil-images/mine/4qex) | Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217 | Descriptor: | Antibody Heavy Chain, Antibody Light Chain, Erythrocyte-binding antigen-175 | Authors: | Chen, E, Paing, M.M, Salinas, N, Sim, B.K, Tolia, N.H. | Deposit date: | 2014-05-19 | Release date: | 2014-06-04 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175. Plos Pathog., 9, 2013
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4ZEW
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![BU of 4zew by Molmil](/molmil-images/mine/4zew) | Crystal structure of PfHAD1 in complex with glucose-6-phosphate | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Park, J, Tolia, N.H. | Deposit date: | 2015-04-20 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4ZEX
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![BU of 4zex by Molmil](/molmil-images/mine/4zex) | Crystal structure of PfHAD1 in complex with glyceraldehyde-3-phosphate | Descriptor: | GLYCERALDEHYDE-3-PHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Park, J, Tolia, N.H. | Deposit date: | 2015-04-20 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4ZEV
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![BU of 4zev by Molmil](/molmil-images/mine/4zev) | Crystal structure of PfHAD1 in complex with mannose-6-phosphate | Descriptor: | 6-O-phosphono-alpha-D-mannopyranose, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Park, J, Tolia, N.H. | Deposit date: | 2015-04-20 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4GF2
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![BU of 4gf2 by Molmil](/molmil-images/mine/4gf2) | Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL) | Descriptor: | Erythrocyte binding antigen 140, GLYCEROL | Authors: | Lin, D.H, Malpede, B.M, Batchelor, J.D, Tolia, N.H. | Deposit date: | 2012-08-02 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion. J.Biol.Chem., 287, 2012
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7U9E
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![BU of 7u9e by Molmil](/molmil-images/mine/7u9e) | Pfs230 D1 domain in complex with 230AL-26 | Descriptor: | 230AL-26, Gametocyte surface protein P230, LMIV230-01 | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-10 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UA8
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![BU of 7ua8 by Molmil](/molmil-images/mine/7ua8) | Pfs230 D1 domain in complex with 230AL-20 | Descriptor: | 230Al-20, Gametocyte surface protein P230 | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-11 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UA2
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![BU of 7ua2 by Molmil](/molmil-images/mine/7ua2) | Pfs230 D1 domain in complex with 230AL-18 | Descriptor: | 230AL-18, Gametocyte surface protein P230, LMIV230-01 | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-11 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7U9W
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![BU of 7u9w by Molmil](/molmil-images/mine/7u9w) | Pfs230 D1 domain in complex with 230AS-88 | Descriptor: | 230AS-88, Gametocyte surface protein P230 | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-11 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UFW
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![BU of 7ufw by Molmil](/molmil-images/mine/7ufw) | Pfs230 D1D2 in complex with LMIV230-01 | Descriptor: | Gametocyte surface protein P230, LMIV230-01 | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-23 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UCQ
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![BU of 7ucq by Molmil](/molmil-images/mine/7ucq) | Pfs230 D1 domain in complex with 230AS-18 | Descriptor: | 230AS-18, Gametocyte surface protein P230 | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-17 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UI1
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![BU of 7ui1 by Molmil](/molmil-images/mine/7ui1) | Pfs230 D1D2 domain in complex with 230AL-37 | Descriptor: | 230AL-37, Gametocyte surface protein P230, SULFATE ION | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-28 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UC8
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![BU of 7uc8 by Molmil](/molmil-images/mine/7uc8) | Pfs230 D1 domain in complex with 230AS-73 | Descriptor: | 230AS-73, Gametocyte surface protein P230, SODIUM ION | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-16 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UBS
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![BU of 7ubs by Molmil](/molmil-images/mine/7ubs) | Pfs230 D1 domain in complex with 230AS-26 | Descriptor: | 230AS-26, Gametocyte surface protein P230 | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-15 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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1Z26
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![BU of 1z26 by Molmil](/molmil-images/mine/1z26) | Structure of Pyrococcus furiosus Argonaute with bound tungstate | Descriptor: | Argonaute, TUNGSTATE(VI)ION | Authors: | Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L. | Deposit date: | 2005-03-07 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Purified Argonaute2 and an siRNA form recombinant human RISC. Nat.Struct.Mol.Biol., 12, 2005
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