3RRC
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4QJB
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4NUU
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4NUV
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4K2U
| Crystal structure of PfEBA-175 F1 in complex with R218 antibody Fab fragment | Descriptor: | Antibody Heavy Chain, Antibody Light Chain, Erythrocyte binding antigen 175, ... | Authors: | Tolia, N.H. | Deposit date: | 2013-04-09 | Release date: | 2013-06-12 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175. Plos Pathog., 9, 2013
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4JNO
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7JUM
| Pfs230 D1 domain in complex with neutralizing antibody LMIV230-01 | Descriptor: | Gametocyte surface protein P230, Neutralizing antibody, LMIV230-01 Single-chain Fv | Authors: | Tolia, N, Tang, W.K. | Deposit date: | 2020-08-20 | Release date: | 2021-03-31 | Last modified: | 2021-04-07 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes. Nat Commun, 12, 2021
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1ZRO
| Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose | Descriptor: | CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II | Authors: | Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L. | Deposit date: | 2005-05-19 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum. Cell(Cambridge,Mass.), 122, 2005
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1ZRL
| Crystal structure of EBA-175 Region II (RII) | Descriptor: | CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II | Authors: | Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L. | Deposit date: | 2005-05-19 | Release date: | 2005-08-09 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum. Cell(Cambridge,Mass.), 122, 2005
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7K3Z
| P. falciparum Cpn60 D474A mutant bound to ATP | Descriptor: | 60 kDa chaperonin, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | Authors: | Tolia, N.H, Shi, D, Nguyen, B. | Deposit date: | 2020-09-14 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.69 Å) | Cite: | Crystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding. Sci Rep, 11, 2021
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5TSZ
| Crystal structure of Plasmodium vivax CelTOS | Descriptor: | Pv cell-traversal protein, SODIUM ION | Authors: | Tolia, N.H, Jimah, J.R. | Deposit date: | 2016-10-31 | Release date: | 2016-12-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption. Elife, 5, 2016
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6OAO
| Structure of DBP in complex with human neutralizing antibody 092096 | Descriptor: | Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION | Authors: | Urusova, D, Tolia, N.H. | Deposit date: | 2019-03-18 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.497 Å) | Cite: | Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP. Nat Microbiol, 4, 2019
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8TWF
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8TWG
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8ULF
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8UKH
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6WG9
| Crystal structure of tetracycline destructase Tet(X7) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Tetracycline destructase Tet(X7) | Authors: | Kumar, H, Tolia, N.H. | Deposit date: | 2020-04-05 | Release date: | 2021-02-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance. Commun Biol, 3, 2020
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5F3J
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6B2N
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8GIF
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8GIE
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8GID
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8DCC
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6O38
| Structure of a chaperone-substrate complex | Descriptor: | Acinetobacter secreted protease CpaA, SULFATE ION, Type II secretion chaperone CpaB, ... | Authors: | Urusova, D.V, Tolia, N.H. | Deposit date: | 2019-02-26 | Release date: | 2019-07-24 | Last modified: | 2019-09-25 | Method: | X-RAY DIFFRACTION (2.595 Å) | Cite: | The structure ofAcinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone-substrate interaction. J.Biol.Chem., 294, 2019
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4QEX
| Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217 | Descriptor: | Antibody Heavy Chain, Antibody Light Chain, Erythrocyte-binding antigen-175 | Authors: | Chen, E, Paing, M.M, Salinas, N, Sim, B.K, Tolia, N.H. | Deposit date: | 2014-05-19 | Release date: | 2014-06-04 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175. Plos Pathog., 9, 2013
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