6B2N

Crystal structure of TEM-1 beta-lactamase mutant M182N

Summary for 6B2N

Entry DOI	10.2210/pdb6b2n/pdb
Descriptor	Beta-lactamase TEM, SULFATE ION (3 entities in total)
Functional Keywords	antibiotic resistance, beta-lactamase, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	116083.85
Authors	Jimah, J.R.,Tolia, N.H. (deposition date: 2017-09-20, release date: 2018-01-17, Last modification date: 2023-10-04)
Primary citation	Zimmerman, M.I.,Hart, K.M.,Sibbald, C.A.,Frederick, T.E.,Jimah, J.R.,Knoverek, C.R.,Tolia, N.H.,Bowman, G.R. Prediction of New Stabilizing Mutations Based on Mechanistic Insights from Markov State Models. ACS Cent Sci, 3:1311-1321, 2017 Cited by PubMed: 29296672 DOI: 10.1021/acscentsci.7b00465 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation