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PDB: 60 件
6O38
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Structure of a chaperone-substrate complex
分子名称: Acinetobacter secreted protease CpaA, SULFATE ION, Type II secretion chaperone CpaB, ...
著者Urusova, D.V, Tolia, N.H.
登録日2019-02-26
公開日2019-07-24
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (2.595 Å)
主引用文献The structure ofAcinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone-substrate interaction.
J.Biol.Chem., 294, 2019
1R6Z
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The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)
分子名称: Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L.
登録日2003-10-17
公開日2004-01-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.
Nat.Struct.Biol., 10, 2003
6OAN
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Structure of DBP in complex with human neutralizing antibody 053054
分子名称: Antibody 053054 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION
著者Urusova, D, Tolia, N.H.
登録日2019-03-18
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
6OAO
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Structure of DBP in complex with human neutralizing antibody 092096
分子名称: Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION
著者Urusova, D, Tolia, N.H.
登録日2019-03-18
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.497 Å)
主引用文献Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
8EZL
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Pfs25 in complex with transmission-reducing antibody AS01-50
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ...
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZM
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Pfs25 in complex with transmission-reducing antibody AS01-63
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ...
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8E1Z
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Crystal structure of Plasmodium falciparum ookinete surface antigen Pfs28
分子名称: CHLORIDE ION, Ookinete surface protein Pfs28, SULFATE ION
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-08-12
公開日2022-11-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design.
Sci Rep, 12, 2022
8EZK
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Pfs25 in complex with transmission-reducing antibody AS01-04
分子名称: 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-4, single-chain Fv
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8ER1
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X-ray crystal structure of Tet(X6)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase
著者Kumar, H, Tolia, N.H.
登録日2022-10-11
公開日2023-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
8ER0
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X-ray crystal structure of Tet(X6) bound to anhydrotetracycline
分子名称: 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase
著者Kumar, H, Tolia, N.H.
登録日2022-10-11
公開日2023-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
4GF2
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BU of 4gf2 by Molmil
Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL)
分子名称: Erythrocyte binding antigen 140, GLYCEROL
著者Lin, D.H, Malpede, B.M, Batchelor, J.D, Tolia, N.H.
登録日2012-08-02
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion.
J.Biol.Chem., 287, 2012
7U9E
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BU of 7u9e by Molmil
Pfs230 D1 domain in complex with 230AL-26
分子名称: 230AL-26, Gametocyte surface protein P230, LMIV230-01
著者Tang, W.K, Tolia, N.H.
登録日2022-03-10
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
5TUK
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BU of 5tuk by Molmil
Crystal structure of tetracycline destructase Tet(51)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Tetracycline destructase Tet(51)
著者Park, J, Tolia, N.H.
登録日2016-11-06
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
5TUI
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BU of 5tui by Molmil
Crystal structure of tetracycline destructase Tet(50) in complex with chlortetracycline
分子名称: 7-CHLOROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
著者Park, J, Tolia, N.H.
登録日2016-11-06
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
5TUE
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BU of 5tue by Molmil
Crystal structure of tetracycline destructase Tet(50)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Tetracycline destructase Tet(50)
著者Park, J, Tolia, N.H.
登録日2016-11-05
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
7UA8
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BU of 7ua8 by Molmil
Pfs230 D1 domain in complex with 230AL-20
分子名称: 230Al-20, Gametocyte surface protein P230
著者Tang, W.K, Tolia, N.H.
登録日2022-03-11
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UA2
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BU of 7ua2 by Molmil
Pfs230 D1 domain in complex with 230AL-18
分子名称: 230AL-18, Gametocyte surface protein P230, LMIV230-01
著者Tang, W.K, Tolia, N.H.
登録日2022-03-11
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7U9W
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BU of 7u9w by Molmil
Pfs230 D1 domain in complex with 230AS-88
分子名称: 230AS-88, Gametocyte surface protein P230
著者Tang, W.K, Tolia, N.H.
登録日2022-03-11
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UFW
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BU of 7ufw by Molmil
Pfs230 D1D2 in complex with LMIV230-01
分子名称: Gametocyte surface protein P230, LMIV230-01
著者Tang, W.K, Tolia, N.H.
登録日2022-03-23
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UCQ
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BU of 7ucq by Molmil
Pfs230 D1 domain in complex with 230AS-18
分子名称: 230AS-18, Gametocyte surface protein P230
著者Tang, W.K, Tolia, N.H.
登録日2022-03-17
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UI1
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Pfs230 D1D2 domain in complex with 230AL-37
分子名称: 230AL-37, Gametocyte surface protein P230, SULFATE ION
著者Tang, W.K, Tolia, N.H.
登録日2022-03-28
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UC8
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Pfs230 D1 domain in complex with 230AS-73
分子名称: 230AS-73, Gametocyte surface protein P230, SODIUM ION
著者Tang, W.K, Tolia, N.H.
登録日2022-03-16
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UBS
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BU of 7ubs by Molmil
Pfs230 D1 domain in complex with 230AS-26
分子名称: 230AS-26, Gametocyte surface protein P230
著者Tang, W.K, Tolia, N.H.
登録日2022-03-15
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
4YFS
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Structure of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for malaria vaccine design
分子名称: Duffy receptor
著者Chen, E, Tolia, N.H.
登録日2015-02-25
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design.
Plos Negl Trop Dis, 9, 2015
4ZEW
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BU of 4zew by Molmil
Crystal structure of PfHAD1 in complex with glucose-6-phosphate
分子名称: 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, PHOSPHATE ION, ...
著者Park, J, Tolia, N.H.
登録日2015-04-20
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015

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件を2024-06-26に公開中

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