4YHX
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4Z20
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3UGM
| Structure of TAL effector PthXo1 bound to its DNA target | Descriptor: | DNA-1, DNA-2, TAL effector AvrBs3/PthA | Authors: | Mak, A.N.S, Bradley, P, Cernadas, R.A, Bogdanove, A.J, Stoddard, B.L. | Deposit date: | 2011-11-02 | Release date: | 2012-01-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target. Science, 335, 2012
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3M7K
| Crystal structure of PacI-DNA Enzyme product complex | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*TP*TP*AP*AP*T)-3'), DNA (5'-D(P*TP*AP*AP*GP*CP*CP*TP*C)-3'), ... | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2010-03-16 | Release date: | 2010-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI. Structure, 18, 2010
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4QPZ
| Crystal structure of the formolase FLS_v2 in space group P 21 | Descriptor: | Formolase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | Authors: | Shen, B.W, Siegel, J.B, Stoddard, B.L, Baker, D. | Deposit date: | 2014-06-25 | Release date: | 2015-03-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Computational protein design enables a novel one-carbon assimilation pathway. Proc.Natl.Acad.Sci.USA, 112, 2015
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3U0S
| Crystal Structure of an Enzyme Redesigned Through Multiplayer Online Gaming: CE6 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Diisopropyl-fluorophosphatase, GLYCEROL, ... | Authors: | Bale, J.B, Shen, B.W, Stoddard, B.L. | Deposit date: | 2011-09-29 | Release date: | 2012-02-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Increased Diels-Alderase activity through backbone remodeling guided by Foldit players. Nat.Biotechnol., 30, 2012
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3HYJ
| Crystal structure of the N-terminal LAGLIDADG domain of DUF199/WhiA | Descriptor: | CHLORIDE ION, GLYCEROL, Protein DUF199/WhiA, ... | Authors: | Kaiser, B.K, Clifton, M.C, Shen, B.W, Stoddard, B.L. | Deposit date: | 2009-06-22 | Release date: | 2009-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structure of a bacterial DUF199/WhiA protein: domestication of an invasive endonuclease. Structure, 17, 2009
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3HYI
| Crystal structure of full-length DUF199/WhiA from Thermatoga maritima | Descriptor: | GLYCEROL, Protein DUF199/WhiA, SODIUM ION | Authors: | Kaiser, B.K, Clifton, M.C, Shen, B.W, Stoddard, B.L. | Deposit date: | 2009-06-22 | Release date: | 2009-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | The structure of a bacterial DUF199/WhiA protein: domestication of an invasive endonuclease Structure, 17, 2009
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3C25
| Crystal Structure of NotI Restriction Endonuclease Bound to Cognate DNA | Descriptor: | CALCIUM ION, DNA (5'-D(*DCP*DGP*DGP*DAP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DGP*DCP*DCP*DG)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DTP*DCP*DCP*DG)-3'), ... | Authors: | Lambert, A.R, Sussman, D, Shen, B, Stoddard, B.L. | Deposit date: | 2008-01-24 | Release date: | 2008-02-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding. Structure, 16, 2008
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5TGX
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3QQY
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8ETQ
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3R7P
| The crystal structure of I-LtrI | Descriptor: | DNA (5'-D(*CP*AP*AP*AP*TP*GP*CP*TP*CP*CP*TP*AP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*GP*CP*AP*TP*TP*TP*G)-3'), ... | Authors: | Mak, A.N.S, Takeuchi, R, Edgell, D.R, Stoddard, B.L. | Deposit date: | 2011-03-22 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.704 Å) | Cite: | Tapping natural reservoirs of homing endonucleases for targeted gene modification. Proc.Natl.Acad.Sci.USA, 108, 2011
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4R6J
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1YSB
| Yeast Cytosine Deaminase Triple Mutant | Descriptor: | CALCIUM ION, Cytosine deaminase, ZINC ION | Authors: | Korkegian, A, Black, M.E, Baker, D, Stoddard, B.L. | Deposit date: | 2005-02-08 | Release date: | 2005-05-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Computational thermostabilization of an enzyme. Science, 308, 2005
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4YY2
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1M5X
| Crystal structure of the homing endonuclease I-MsoI bound to its DNA substrate | Descriptor: | 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... | Authors: | Chevalier, B, Turmel, M, Lemieux, C, Monnat, R.J, Stoddard, B.L. | Deposit date: | 2002-07-10 | Release date: | 2003-06-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI J.Mol.Biol., 329, 2003
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3BVQ
| Crystal Structure of Apo NotI Restriction Endonuclease | Descriptor: | FE (III) ION, NotI restriction endonuclease, SULFATE ION | Authors: | Lambert, A.R, Sussman, D, Shen, B, Stoddard, B.L. | Deposit date: | 2008-01-07 | Release date: | 2008-01-22 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding. Structure, 16, 2008
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2O3K
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1YSD
| Yeast Cytosine Deaminase Double Mutant | Descriptor: | CALCIUM ION, Cytosine deaminase, ZINC ION | Authors: | Korkegian, A, Black, M.E, Baker, D, Stoddard, B.L. | Deposit date: | 2005-02-08 | Release date: | 2005-05-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Computational thermostabilization of an enzyme. Science, 308, 2005
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4Z1Z
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5TH3
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1N3E
| Crystal structure of I-CreI bound to a palindromic DNA sequence I (palindrome of left side of wildtype DNA target sequence) | Descriptor: | 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3', 5'-D(P*GP*AP*CP*GP*TP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... | Authors: | Chevalier, B, Turmel, M, Lemieux, C, Monnat, R.J, Stoddard, B.L. | Deposit date: | 2002-10-28 | Release date: | 2003-06-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI J.Mol.Biol., 329, 2003
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8EM1
| Type IIS Restriction Endonuclease PaqCI, DNA Unbound | Descriptor: | 1,2-ETHANEDIOL, PaqCI, DNA Unbound | Authors: | Kennedy, M.A, Stoddard, B.L. | Deposit date: | 2022-09-26 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI. Nucleic Acids Res., 51, 2023
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2EX5
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