4WS9
| Crystal structure of sMAT N159G from Sulfolobus solfataricus | 分子名称: | PHOSPHATE ION, S-adenosylmethionine synthase | 著者 | Wang, F, Brady, E.L, Singh, S, Clinger, J.A, Huber, T.D, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2014-10-26 | 公開日 | 2014-11-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | 主引用文献 | Crystal structure of sMAT N159G from Sulfolobus solfataricus. To Be Published
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6ND7
| The crystal structure of TerB co-crystallized with polyporic acid | 分子名称: | 2~3~,2~6~-dihydroxy[1~1~,2~1~:2~4~,3~1~-terphenyl]-2~2~,2~5~-dione, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Clinger, J.A, Elshahawi, S.I, Zhang, Y, Hall, R.P, Liu, Y, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2018-12-13 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC To Be Published
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4M83
| Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A | 分子名称: | ERYTHROMYCIN A, MAGNESIUM ION, Oleandomycin glycosyltransferase, ... | 著者 | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2013-08-12 | 公開日 | 2013-09-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Crystal structure of macrolide glycosyltransferases OleD To be Published
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4M60
| Crystal structure of macrolide glycosyltransferases OleD | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Oleandomycin glycosyltransferase, SODIUM ION | 著者 | Olmos Jr, J.L, Martinez III, E, Wang, F, Helmich, K.E, Singh, S, Xu, W, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2013-08-08 | 公開日 | 2013-09-04 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Crystal structure of macrolide glycosyltransferases OleD To be Published
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5EEH
| Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with SAH and 2-chloro-4-nitrophenol | 分子名称: | 2-chloranyl-4-nitro-phenol, Carminomycin 4-O-methyltransferase DnrK, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Wang, F, Singh, S, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2015-10-22 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. Acs Chem.Biol., 11, 2016
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5EEG
| Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with tetrazole-SAH | 分子名称: | (2~{R},3~{R},4~{S},5~{S})-2-(6-aminopurin-9-yl)-5-[[(3~{S})-3-azanyl-3-(1~{H}-1,2,3,4-tetrazol-5-yl)propyl]sulfanylmethyl]oxolane-3,4-diol, Carminomycin 4-O-methyltransferase DnrK | 著者 | Wang, F, Singh, S, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2015-10-22 | 公開日 | 2015-12-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.255 Å) | 主引用文献 | Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. Acs Chem.Biol., 11, 2016
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6D2V
| Apo Structure of TerB, an NADP Dependent Oxidoreductase in the Terfestatin Biosynthesis Pathway | 分子名称: | CHLORIDE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, THIOCYANATE ION, ... | 著者 | Clinger, J.A, Elshahawi, S.I, Zhang, Y, Hall, R.P, Liu, Y, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2018-04-14 | 公開日 | 2018-06-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC To Be Published
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6D34
| Apo Crystal Structure of TerC, a Terfestatin Biosynthesis Enzyme | 分子名称: | ISOPROPYL ALCOHOL, TerC | 著者 | Clinger, J.A, Elshahawi, S.I, Zhang, Y, Hall, R.P, Liu, Y, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2018-04-14 | 公開日 | 2018-06-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC To Be Published
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6WF4
| Crystal Structure of TerC Co-crystallized with Polyporic Acid | 分子名称: | (2~5~S)-2~3~,2~5~,2~6~-trihydroxy[1~1~,2~1~:2~4~,3~1~-terphenyl]-2~2~(2~5~H)-one, ISOPROPYL ALCOHOL, Terfestatin Biosyntheis Enzyme C | 著者 | Clinger, J.A, Miller, M.D, Hall, R.E, Zhang, Y, Elshahawi, S.I, Thorson, J.S, Van Lanen, S.G, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2020-04-03 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural and functional characterization of two cooperative enzymes responsible for the stability
of p-terphenyls. To be published
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3LST
| Crystal Structure of CalO1, Methyltransferase in Calicheamicin Biosynthesis, SAH bound form | 分子名称: | 1,2-ETHANEDIOL, CalO1 Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2010-02-12 | 公開日 | 2010-03-02 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway. Acta Crystallogr.,Sect.D, 67, 2011
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7MSY
| Structure of CalU17 from the Calicheamicin Biosynthesis Pathway of Micromonospora echinospora | 分子名称: | CALCIUM ION, CHLORIDE ION, CalU17, ... | 著者 | Kosgei, A.J, Miller, M.D, Xu, W, Van Lanen, S.G, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2021-05-12 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina. Acta Crystallogr.,Sect.F, 78, 2022
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7ML6
| Structure of CalU17 from the Calicheamicin Biosynthesis Pathway of Micromonospora echinospora | 分子名称: | CalU17, GLYCEROL | 著者 | Kosgei, A.J, Miller, M.D, Xu, W, Van Lanen, S.G, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2021-04-27 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina. Acta Crystallogr.,Sect.F, 78, 2022
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3TOS
| Crystal Structure of CalS11, Calicheamicin Methyltransferase | 分子名称: | 1,2-ETHANEDIOL, CalS11, GLUTAMIC ACID, ... | 著者 | Chang, A, Aceti, D.J, Beebe, E.T, Makino, S.-I, Wrobel, R.L, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2011-09-06 | 公開日 | 2011-10-05 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal Structure of CalS11, Calicheamicin methyltransferase To be Published
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1ZXF
| Solution structure of a self-sacrificing resistance protein, CalC from Micromonospora echinospora | 分子名称: | CalC | 著者 | Singh, S, Hager, M.H, Zhang, C, Griffith, B.R, Lee, M.S, Hallenga, K, Markley, J.L, Thorson, J.S, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2005-06-08 | 公開日 | 2005-12-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural insight into the self-sacrifice mechanism of enediyne resistance. Acs Chem.Biol., 1, 2006
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4G2T
| Crystal Structure of Streptomyces sp. SF2575 glycosyltransferase SsfS6, complexed with thymidine diphosphate | 分子名称: | SsfS6, THYMIDINE-5'-DIPHOSPHATE | 著者 | Wang, F, Zhou, M, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-07-12 | 公開日 | 2012-07-25 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins, 81, 2013
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4FZR
| Crystal Structure of SsfS6, Streptomyces sp. SF2575 glycosyltransferase | 分子名称: | SsfS6 | 著者 | Wang, F, Zhou, M, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-07-07 | 公開日 | 2012-07-25 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins, 81, 2013
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3GWZ
| Structure of the Mitomycin 7-O-methyltransferase MmcR | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, MmcR, ... | 著者 | Singh, S, Chang, A, Bingman, C.A, Phillips Jr, G.N, Thorson, J.S. | 登録日 | 2009-04-01 | 公開日 | 2010-04-07 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structural characterization of the mitomycin 7-O-methyltransferase. Proteins, 79, 2011
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3GXO
| Structure of the Mitomycin 7-O-methyltransferase MmcR with bound Mitomycin A | 分子名称: | CALCIUM ION, MmcR, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Singh, S, Chang, A, Bingman, C.A, Phillips Jr, G.N, Thorson, J.S. | 登録日 | 2009-04-02 | 公開日 | 2010-04-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural characterization of the mitomycin 7-O-methyltransferase. Proteins, 79, 2011
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3IAA
| Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP bound form | 分子名称: | CalG2, THYMIDINE-5'-DIPHOSPHATE | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2009-07-13 | 公開日 | 2010-06-02 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.505 Å) | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc.Natl.Acad.Sci.USA, 108, 2011
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3IA7
| Crystal Structure of CalG4, the Calicheamicin Glycosyltransferase | 分子名称: | CALCIUM ION, CHLORIDE ION, CalG4 | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2009-07-13 | 公開日 | 2010-06-02 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OTI
| Crystal Structure of CalG3, Calicheamicin Glycostyltransferase, TDP and calicheamicin T0 bound form | 分子名称: | CHLORIDE ION, CalG3, Calicheamicin T0, ... | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2010-09-11 | 公開日 | 2010-12-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.597 Å) | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc.Natl.Acad.Sci.USA, 108, 2011
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3PKP
| Q83S Variant of S. Enterica RmlA with dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Glucose-1-phosphate thymidylyltransferase, MAGNESIUM ION | 著者 | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2010-11-11 | 公開日 | 2011-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution. J.Biol.Chem., 286, 2011
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3PKQ
| Q83D Variant of S. Enterica RmlA with dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Glucose-1-phosphate thymidylyltransferase, ... | 著者 | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2010-11-11 | 公開日 | 2011-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution. J.Biol.Chem., 286, 2011
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3OTH
| Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP and calicheamicin alpha3I bound form | 分子名称: | CalG1, Calicheamicin alpha3I, THYMIDINE-5'-DIPHOSPHATE | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2010-09-11 | 公開日 | 2010-12-15 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OTG
| Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP bound form | 分子名称: | CHLORIDE ION, CalG1, THYMIDINE-5'-DIPHOSPHATE | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2010-09-11 | 公開日 | 2010-12-15 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc.Natl.Acad.Sci.USA, 108, 2011
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