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PDB: 44 件
9DZM
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BU of 9dzm by Molmil
Dimeric human OCT2 (POU2F2) POU domain bound to palindromic MORE DNA
分子名称: BROMIDE ION, DNA (5'-D(*TP*CP*CP*TP*CP*AP*TP*GP*CP*AP*TP*AP*TP*GP*CP*AP*TP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*CP*AP*TP*GP*CP*AP*TP*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*A)-3'), ...
著者Terrell, J.R, Poon, G.M.K.
登録日2024-10-16
公開日2024-10-23
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Coupled heterogeneity to dimeric site-specific binding by the POU-Family Transcription Factor OCT2
To Be Published
9D2X
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BU of 9d2x by Molmil
SpiD ETS-domain (168-273) in complex with the DNA sequence d(AATAAAAGGAAGTGGG)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), ...
著者Terrell, J.R, Vernon, T.N, Poon, G.M.K.
登録日2024-08-09
公開日2024-10-30
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献The Structure of the DNA-binding Domain of the Class III ETS-Family Member SpiD from Raja eglanteria
To be published
8SMJ
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BU of 8smj by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAATGGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2023-04-26
公開日2023-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SMH
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BU of 8smh by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2023-04-26
公開日2023-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8SP1
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BU of 8sp1 by Molmil
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGIAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2023-05-01
公開日2023-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8T4N
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BU of 8t4n by Molmil
DB1976 Bound to the DNA Sequence 5'-CGCGAATTCGCG-3
分子名称: (2M,2'M)-2,2'-(selenophene-2,5-diyl)di(1H-benzimidazole-6-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
著者Terrell, J.R, Poon, G.M.K, Wilson, W.D.
登録日2023-06-09
公開日2024-06-12
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural studies on the PU.1 inhibitory mechanism by diamidine minor groove binders
To Be Published
8T9U
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BU of 8t9u by Molmil
Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2023-06-26
公開日2023-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8V9N
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BU of 8v9n by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAGAAGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*GP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Ogbonna, E.N, Poon, G.M.K, Wilson, W.D.
登録日2023-12-08
公開日2024-10-02
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural Characterization of GC Base Pair Recognition by a Diamidine Small Molecule
To Be Published
8V4T
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BU of 8v4t by Molmil
The Native DNA 16-mer sequence 5'-GCTGCGTTAACGCAGC-3
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*CP*GP*TP*TP*AP*AP*CP*GP*CP*AP*GP*C)-3')
著者Terrell, J.R, Wilson, W.D.
登録日2023-11-29
公開日2024-10-02
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural Examination of DNA Minor Groove Binding by Diamidine Stacked Dimers
To Be Published
8UHK
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BU of 8uhk by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AAAATAAAAGGAAGTG)
分子名称: DNA (5'-D(*AP*AP*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*TP*TP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K, Wilson, W.D.
登録日2023-10-09
公開日2024-10-16
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Structural studies on the PU.1 inhibitory mechanism by diamidine minor groove binders
To Be Published
8UFZ
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BU of 8ufz by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGCGGAAGTG) in Ternary Complex with DB1976
分子名称: (2M,2'M)-2,2'-(selenophene-2,5-diyl)di(1H-benzimidazole-6-carboximidamide), DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*TP*TP*AP*T)-3'), ...
著者Terrell, J.R, Poon, G.M.K, Wilson, W.D.
登録日2023-10-05
公開日2024-10-09
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Structural studies on the PU.1 inhibitory mechanism by diamidine minor groove binders
To Be Published
8UFF
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BU of 8uff by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG) in Ternary Complex with DB1976
分子名称: (2M,2'M)-2,2'-(selenophene-2,5-diyl)di(1H-benzimidazole-6-carboximidamide), DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), ...
著者Terrell, J.R, Poon, G.M.K, Wilson, W.D.
登録日2023-10-04
公開日2024-10-09
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural studies on the PU.1 inhibitory mechanism by diamidine minor groove binders
To Be Published
8UFK
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BU of 8ufk by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGCGGAAGTG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K, Wilson, W.D.
登録日2023-10-04
公開日2024-10-09
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structural studies on the PU.1 inhibitory mechanism by diamidine minor groove binders
To Be Published
8VDI
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BU of 8vdi by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) in Ternary Complex with DB2447
分子名称: 4,4'-[pyridine-2,6-diylbis(methyleneoxy)]di(benzene-1-carboximidamide), DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), ...
著者Terrell, J.R, Ogbonna, E.N, Poon, G.M.K, Wilson, W.D.
登録日2023-12-15
公開日2024-09-18
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural Characterization of GC Base Pair Recognition by a Diamidine Small Molecule
To Be Published
8VDH
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BU of 8vdh by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAGAAGGAAGTGGG) in Ternary Complex with DB2447
分子名称: 4,4'-[pyridine-2,6-diylbis(methyleneoxy)]di(benzene-1-carboximidamide), DNA (5'-D(*AP*AP*TP*AP*GP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*TP*AP*T)-3'), ...
著者Terrell, J.R, Ogbonna, E.N, Poon, G.M.K, Wilson, W.D.
登録日2023-12-15
公開日2024-09-18
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural Characterization of GC Base Pair Recognition by a Diamidine Small Molecule
To Be Published
8VIU
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BU of 8viu by Molmil
The DNA 16-mer sequence 5'-GCTGCGTTAACGCAGC-3' bound by a DB1992 stacked dimer
分子名称: (2M)-2-[(5P)-5-(5-carbamimidoylthiophen-2-yl)furan-2-yl]-1H-benzimidazole-6-carboximidamide, CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*CP*GP*TP*TP*AP*AP*CP*GP*CP*AP*GP*C)-3')
著者Terrell, J.R, Wilson, W.D.
登録日2024-01-05
公開日2024-10-02
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural Examination of DNA Minor Groove Binding by Diamidine Stacked Dimers
To Be Published
8UTG
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BU of 8utg by Molmil
An RNA G-Quadruplex from the NS5 gene in the West Nile Virus Genome
分子名称: AMMONIUM ION, POTASSIUM ION, RNA (5'-R(*UP*AP*UP*GP*GP*AP*AP*GP*AP*GP*GP*CP*GP*GP*UP*UP*GP*GP*UP*AP*U)-3')
著者Terrell, J.R, Le, T.T, Wilson, W.D, Siemer, J.L.
登録日2023-10-31
公開日2024-06-19
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of an RNA G-quadruplex from the West Nile virus genome.
Nat Commun, 15, 2024
8E4H
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BU of 8e4h by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2022-08-18
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8E3R
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BU of 8e3r by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2022-08-17
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8E3K
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BU of 8e3k by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-08-17
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8E5Y
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BU of 8e5y by Molmil
Human PU.1 ETS-Domain Bound to d(AATAAGCGGAAGTGGG) Acetate Free at pH 5.4
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-08-22
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EBH
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BU of 8ebh by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAATGGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2022-08-31
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EQG
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BU of 8eqg by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAA(DU)GGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*DU*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-10-07
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EK3
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BU of 8ek3 by Molmil
Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-19
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EKV
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BU of 8ekv by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGATGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*TP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*AP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-22
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023

 

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