8UFZ

Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGCGGAAGTG) in Ternary Complex with DB1976

Summary for 8UFZ

• Entry DOI: 10.2210/pdb8ufz/pdb
• Related: 8T4N 8UFF 8UFK
• Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1, ... (4 entities in total)
• Functional Keywords: transcription factor, protein-dna complex, ets family, ets, pu.1, transcription-dna complex, diamidine, minor-groove binder, transcription inhibition, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 45356.69

Authors

Terrell, J.R.,Poon, G.M.K.,Wilson, W.D. (deposition date: 2023-10-05, release date: 2024-10-09)

• Primary citation: Terrell, J.R.,Paul, A.,Ogbonna, E.N.,Farahat, A.A.,Poon, G.M.K.,Wilson, W.D.; Structural studies on the PU.1 inhibitory mechanism by diamidine minor groove binders; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.06 Å)