1XKD
 
 | | Ternary complex of Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix | | 分子名称: | CALCIUM ION, ISOCITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Karlstrom, M, Stokke, R, Steen, I.H, Birkeland, N.-K, Ladenstein, R. | | 登録日 | 2004-09-28 | | 公開日 | 2005-10-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability.
J.Mol.Biol., 345, 2005
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1GMY
 | | Cathepsin B complexed with dipeptidyl nitrile inhibitor | | 分子名称: | 2-AMINOETHANIMIDIC ACID, 3-METHYLPHENYLALANINE, CATHEPSIN B, ... | | 著者 | Greenspan, P.D, Clark, K.L, Tommasi, R.A, Cowen, S.D, McQuire, L.W, Farley, D.L, van Duzer, J.H, Goldberg, R.L, Zhou, H, Du, Z, Fitt, J.J, Coppa, D.E, Fang, Z, Macchia, W, Zhu, L, Capparelli, M.P, Goldstein, R, Wigg, A.M, Doughty, J.R, Bohacek, R.S, Knap, A.K. | | 登録日 | 2001-09-25 | | 公開日 | 2002-09-19 | | 最終更新日 | 2017-07-05 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B Through Structure-Based Drug Design
J.Med.Chem., 44, 2001
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7LIW
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4GS4
 | | Structure of the alpha-tubulin acetyltransferase, alpha-TAT1 | | 分子名称: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase | | 著者 | Friedmann, D.R, Fan, J, Marmorstein, R. | | 登録日 | 2012-08-27 | | 公開日 | 2012-10-17 | | 最終更新日 | 2013-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.112 Å) | | 主引用文献 | Structure of the alpha-tubulin acetyltransferase, alpha TAT1, and implications for tubulin-specific acetylation.
Proc.Natl.Acad.Sci.USA, 109, 2012
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7LLA
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3N5U
 | | Crystal structure of an Rb C-terminal peptide bound to the catalytic subunit of PP1 | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Retinoblastoma-associated protein, ... | | 著者 | Hirschi, A.M, Cecchini, M, Steinhardt, R.C, Dick, F.A, Rubin, S.M. | | 登録日 | 2010-05-25 | | 公開日 | 2010-08-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.
Nat.Struct.Mol.Biol., 17, 2010
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4K2J
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1ZOR
 | | Isocitrate dehydrogenase from the hyperthermophile Thermotoga maritima | | 分子名称: | SODIUM ION, isocitrate dehydrogenase | | 著者 | Karlstrom, M, Steen, I.H, Birkeland, N.-K, Ladenstein, R. | | 登録日 | 2005-05-13 | | 公開日 | 2006-05-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima.
Febs J., 273, 2006
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7RZD
 | | CRYSTAL STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PEPTIDE | | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | | 著者 | Patskovsky, Y, Patskovska, L, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. | | 登録日 | 2021-08-27 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
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1YK5
 | | Pyrococcus abyssi rubredoxin | | 分子名称: | FE (III) ION, Rubredoxin | | 著者 | Bonisch, H, Schmidt, C.L, Bianco, P, Ladenstein, R. | | 登録日 | 2005-01-17 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Ultrahigh-resolution study on Pyrococcus abyssi rubredoxin. I. 0.69 A X-ray structure of mutant W4L/R5S.
Acta Crystallogr.,Sect.D, 61, 2005
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2PHE
 | | Model for VP16 binding to PC4 | | 分子名称: | Alpha trans-inducing protein, TRANSCRIPTIONAL COACTIVATOR PC4 | | 著者 | Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R. | | 登録日 | 2007-04-11 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Properties of the Promiscuous VP16 Activation Domain
Biochemistry, 44, 2005
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4DAW
 | | Crystal structure of PAK1 kinase domain with the ruthenium phthalimide complex | | 分子名称: | Serine/threonine-protein kinase PAK 1, [1,3-dioxo-6-(pyridin-2-yl-kappaN)-2,3-dihydro-1H-isoindol-5-yl-kappaC~5~][(thioxomethylidene)azanido-kappaN](1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium | | 著者 | Maksimoska, J, Marmorstein, R. | | 登録日 | 2012-01-13 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The art of filling protein pockets efficiently with octahedral metal complexes.
Angew.Chem.Int.Ed.Engl., 51, 2012
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5DFP
 | | Crystal structure of PAK1 in complex with an inhibitor compound FRAX1036 | | 分子名称: | 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, DIMETHYL SULFOXIDE, Serine/threonine-protein kinase PAK 1 | | 著者 | Maksimoska, J, Marmorstein, R, Wang, W. | | 登録日 | 2015-08-27 | | 公開日 | 2016-01-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.
Acs Med.Chem.Lett., 6, 2015
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3Q35
 | | Structure of the Rtt109-AcCoA/Vps75 complex and implications for chaperone-mediated histone acetylation | | 分子名称: | 1,2-ETHANEDIOL, ACETYL COENZYME *A, Histone acetyltransferase, ... | | 著者 | Tang, Y, Yuan, H, Meeth, K, Marmorstein, R. | | 登録日 | 2010-12-21 | | 公開日 | 2011-02-02 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation.
Structure, 19, 2011
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7L1K
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4EQC
 | | Crystal structure of PAK1 kinase domain in complex with FRAX597 inhibitor | | 分子名称: | 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, CHLORIDE ION, Serine/threonine-protein kinase PAK 1 | | 著者 | Maksimoska, J, Marmorstein, R. | | 登録日 | 2012-04-18 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas.
J.Biol.Chem., 288, 2013
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2PHG
 | | Model for VP16 binding to TFIIB | | 分子名称: | Alpha trans-inducing protein, Transcription initiation factor IIB | | 著者 | Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R. | | 登録日 | 2007-04-11 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Properties of the Promiscuous VP16 Activation Domain
Biochemistry, 44, 2005
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3Q33
 | | Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation | | 分子名称: | 1,2-ETHANEDIOL, ACETYL COENZYME *A, HISTONE H3, ... | | 著者 | Tang, Y, Yuan, H, Meeth, K, Marmorstein, R. | | 登録日 | 2010-12-21 | | 公開日 | 2011-02-02 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation.
Structure, 19, 2011
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2P4W
 | | Crystal structure of heat shock regulator from Pyrococcus furiosus | | 分子名称: | SULFATE ION, Transcriptional regulatory protein arsR family | | 著者 | Liu, W, Vierke, G, Panjikar, S, Thomm, M, Ladenstein, R. | | 登録日 | 2007-03-13 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the Archaeal Heat Shock Regulator from Pyrococcus furiosus: A Molecular Chimera Representing Eukaryal and Bacterial Features.
J.Mol.Biol., 369, 2007
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2QIY
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2R7G
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2VL6
 | | STRUCTURAL ANALYSIS OF THE SULFOLOBUS SOLFATARICUS MCM PROTEIN N- TERMINAL DOMAIN | | 分子名称: | MINICHROMOSOME MAINTENANCE PROTEIN MCM, ZINC ION | | 著者 | Liu, W, Pucci, B, Rossi, M, Pisani, F.M, Ladenstein, R. | | 登録日 | 2008-01-08 | | 公開日 | 2008-04-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Analysis of the Sulfolobus Solfataricus Mcm Protein N-Terminal Domain.
Nucleic Acids Res., 36, 2008
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3IOQ
 | | Crystal structure of the Carica candamarcensis cysteine protease CMS1MS2 in complex with E-64. | | 分子名称: | 1,2-ETHANEDIOL, CMS1MS2, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, ... | | 著者 | Gomes, M.T.R, Teixeira, R.D, Salas, C.E, Nagem, R.A.P. | | 登録日 | 2009-08-14 | | 公開日 | 2010-02-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Crystal structure of the Carica candamarcensis cysteine protease CMS1MS2 in complex with E-64
To be Published
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1WCO
 | | The solution structure of the nisin-lipid II complex | | 分子名称: | (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALA-FGA-LYS-DAL-DAL PEPTIDE, ... | | 著者 | Hsu, S.-T.D, Breukink, E, Tischenko, E, Lutters, M.A.G, de Kruijff, B, Kaptein, R, Bonvin, A.M.J.J, van Nuland, N.A.J. | | 登録日 | 2004-11-19 | | 公開日 | 2005-03-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics.
Nat. Struct. Mol. Biol., 11, 2004
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2VLD
 | | crystal structure of a repair endonuclease from Pyrococcus abyssi | | 分子名称: | Endonuclease NucS | | 著者 | Ren, B, Kuhn, J, Meslet-Cladiere, L, Briffotaux, J, Norais, C, Lavigne, R, Flament, D, Ladenstein, R, Myllykallio, H. | | 登録日 | 2008-01-14 | | 公開日 | 2009-05-19 | | 最終更新日 | 2018-09-26 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure and function of a novel endonuclease acting on branched DNA substrates.
EMBO J., 28, 2009
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