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PDB: 437 件

1B28
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ARC REPRESSOR MYL MUTANT FROM SALMONELLA BACTERIOPHAGE P22
分子名称: PROTEIN (REGULATORY PROTEIN ARC)
著者Rietveld, A.W.M, Nooren, I.M.A, Sauer, R.T, Kaptein, R, Boelens, R.
登録日1998-12-05
公開日1999-11-03
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The solution structure and dynamics of an Arc repressor mutant reveal premelting conformational changes related to DNA binding.
Biochemistry, 38, 1999
1T3O
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Solution structure of CsrA, a bacterial carbon storage regulatory protein
分子名称: Carbon storage regulator
著者Koharudin, L.M.I, Georgiou, T, Kleanthous, C, Geoffrey, R, Kaptein, R, Boelens, R.
登録日2004-04-27
公開日2005-10-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A model for RNA binding by the bacterial carbon storage regulatory protein, CsrA
To be Published
1B14
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Alcohol Dehydrogenase from Drosophila Lebanonensis Binary Complex with NAD+
分子名称: ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Benach, J, Atrian, S, Gonzalez-Duarte, R, Ladenstein, R.
登録日1998-11-25
公開日1999-11-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1LEB
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SOLUTION STRUCTURE OF THE LEXA REPRESSOR DNA BINDING DETERMINED BY 1H NMR SPECTROSCOPY
分子名称: LEXA REPRESSOR DNA BINDING DOMAIN
著者Fogh, R.H, Ottleben, G, Rueterjans, H, Schnarr, M, Boelens, R, Kaptein, R.
登録日1994-05-11
公開日1994-08-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the LexA repressor DNA binding domain determined by 1H NMR spectroscopy.
EMBO J., 13, 1994
3TO7
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Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated
分子名称: CACODYLIC ACID, COENZYME A, GLYCEROL, ...
著者Yuan, H, Ding, E.C, Marmorstein, R.
登録日2011-09-04
公開日2011-11-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
2CKC
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Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction
分子名称: CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
著者Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E.
登録日2006-04-14
公開日2007-05-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published
1SFV
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PORCINE PANCREAS PHOSPHOLIPASE A2, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Van Den Berg, B, Tessari, M, Boelens, R, Dijkman, R, Kaptein, R, De Haas, G.H, Verheij, H.M.
登録日1996-02-20
公開日1996-07-11
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor.
J.Biomol.NMR, 5, 1995
1SFW
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PORCINE PANCREAS PHOSPHOLIPASE A2, NMR, 18 STRUCTURES
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Van Den Berg, B, Tessari, M, Boelens, R, Dijkman, R, Kaptein, R, De Haas, G.H, Verheij, H.M.
登録日1996-02-23
公開日1996-07-11
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor.
J.Biomol.NMR, 5, 1995
3CO7
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Crystal Structure of FoxO1 DBD Bound to DBE2 DNA
分子名称: DNA (5'-D(*DCP*DAP*DAP*DAP*DAP*DTP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DGP*DA)-3'), DNA (5'-D(*DTP*DCP*DTP*DTP*DGP*DTP*DTP*DTP*DAP*DCP*DAP*DTP*DTP*DTP*DTP*DG)-3'), Forkhead box protein O1
著者Brent, M.M, Anand, R, Marmorstein, R.
登録日2008-03-27
公開日2008-09-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure, 16, 2008
1CM0
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CRYSTAL STRUCTURE OF THE PCAF/COENZYME-A COMPLEX
分子名称: COENZYME A, P300/CBP ASSOCIATING FACTOR
著者Clements, A, Rojas, J.R, Trievel, R.C, Wang, L, Berger, S.L, Marmorstein, R.
登録日1999-05-12
公開日1999-07-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A.
EMBO J., 18, 1999
3CO6
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Crystal Structure of FoxO1 DBD Bound to DBE1 DNA
分子名称: CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DCP*DAP*DAP*DGP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), ...
著者Brent, M.M, Anand, R, Marmorstein, R.
登録日2008-03-27
公開日2008-09-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure, 16, 2008
3COA
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Crystal Structure of FoxO1 DBD Bound to IRE DNA
分子名称: CALCIUM ION, DNA (5'-D(*DCP*DAP*DAP*DGP*DCP*DAP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DG)-3'), ...
著者Brent, M.M, Anand, R, Marmorstein, R.
登録日2008-03-27
公開日2008-09-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure, 16, 2008
1MG5
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Crystal structure of Drosophila melanogaster alcohol dehydrogenase complexed with NADH and acetate at 1.6 A
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ACETATE ION, alcohol dehydrogenase
著者Benach, J, Atrian, S, Gonzalez-Duarte, R, Ladenstein, R.
登録日2002-08-14
公開日2003-10-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Drosophila alcohol dehydrogenase: acetate-enzyme interactions and novel insights into the effects of electrostatics on catalysis
J.Mol.Biol., 345, 2005
2FQ3
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Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes
分子名称: Transcription regulatory protein SWI3
著者Da, G, Lenkart, J, Zhao, K, Shiekhattar, R, Cairns, B.R, Marmorstein, R.
登録日2006-01-17
公開日2006-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes
Proc.Natl.Acad.Sci.Usa, 103, 2006
2IV0
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Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers
分子名称: CHLORIDE ION, ISOCITRATE DEHYDROGENASE, ZINC ION
著者Stokke, R, Karlstrom, M, Yang, N, Leiros, I, Ladenstein, R, Birkeland, N.K, Steen, I.H.
登録日2006-06-08
公開日2007-04-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Thermal Stability of Isocitrate Dehydrogenase from Archaeoglobus Fulgidus Studied by Crystal Structure Analysis and Engineering of Chimers
Extremophiles, 11, 2007
4C4K
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Crystal structure of the titin M10-Obscurin Ig domain 1 complex
分子名称: 1,2-ETHANEDIOL, OBSCURIN, TITIN
著者Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A.
登録日2013-09-05
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module.
J.Mol.Biol., 427, 2015
1PKV
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The N-terminal domain of riboflavin synthase in complex with riboflavin
分子名称: RIBOFLAVIN, Riboflavin synthase alpha chain
著者Meining, W, Eberhardt, S, Bacher, A, Ladenstein, R.
登録日2003-06-06
公開日2004-06-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure of the N-terminal domain of riboflavin synthase in complex with riboflavin at 2.6A resolution.
J.Mol.Biol., 331, 2003
2JFB
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3D Structure of Lumazine Synthase from Candida albicans
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE, PHOSPHATE ION
著者Morgunova, E, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R.
登録日2007-01-30
公開日2007-05-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Lumazine Synthase from Candida Albicans as an Anti- Fungal Target Enzyme: Structural and Biochemical Basis for Drug Design.
J.Biol.Chem., 282, 2007
3KSL
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Structure of FPT bound to DATFP-DH-GPP
分子名称: (2S,6E)-8-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}-2,6-dimethyloct-6-en-1-yl (2S)-3,3,3-trifluoro-2-hydrazinopropanoate, Farnesyltransferase, CAAX box, ...
著者Hovlid, M.L, Edelstein, R.L, Henry, O, Ochocki, J, DeGraw, A, Lenevich, S, Talbot, T, Young, V, Hruza, A.W, Lopez-Gallego, F, Labello, N.P, Strickland, C.L, Schmidt-Dannert, C, Distefano, M.D.
登録日2009-11-23
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability.
Chem.Biol.Drug Des., 75, 2010
1SZD
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Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, GLYCEROL, ...
著者Zhao, K, Harshaw, R, Chai, X, Marmorstein, R.
登録日2004-04-05
公開日2004-06-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Proc.Natl.Acad.Sci.Usa, 101, 2004
4F2U
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Structure of the N254Y/H258Y double mutant of the Phosphatidylinositol-Specific Phospholipase C from S.aureus
分子名称: 1-phosphatidylinositol phosphodiesterase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION
著者Cheng, J, Goldstein, R, Stec, B, Gershenson, A, Roberts, M.F.
登録日2012-05-08
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity.
J.Biol.Chem., 287, 2012
4F2T
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Modulation of S.aureus Phosphatidylinositol-Specific Phospholipase C Membrane Binding.
分子名称: 1-phosphatidylinositol phosphodiesterase, ACETATE ION
著者Cheng, J, Goldstein, R, Stec, B, Gershenson, A, Roberts, M.F.
登録日2012-05-08
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity.
J.Biol.Chem., 287, 2012
1QEY
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NMR Structure Determination of the Tetramerization Domain of the MNT Repressor: An Asymmetric A-Helical Assembly in Slow Exchange
分子名称: PROTEIN (REGULATORY PROTEIN MNT)
著者Nooren, I.M.A, George, A.V.E, Kaptein, R, Sauer, R.T, Boelens, R.
登録日1999-04-03
公開日1999-08-18
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The tetramerization domain of the Mnt repressor consists of two right-handed coiled coils.
Nat.Struct.Biol., 6, 1999
3R6B
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Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3
分子名称: 1,2-ETHANEDIOL, Thrombospondin-1
著者Page, R.C, Klenotic, P.A, Misra, S, Silverstein, R.L.
登録日2011-03-21
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.
Protein Expr.Purif., 80, 2011
1QSR
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CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND ACETYL-COENZYME A
分子名称: ACETYL COENZYME *A, TGCN5 HISTONE ACETYL TRANSFERASE
著者Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R.
登録日1999-06-23
公開日1999-09-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999

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