3KSL
Structure of FPT bound to DATFP-DH-GPP
Summary for 3KSL
Entry DOI | 10.2210/pdb3ksl/pdb |
Descriptor | Farnesyltransferase, CAAX box, alpha, Protein farnesyltransferase subunit beta, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | transferase, prenyltransferase, metal-binding, phosphoprotein, zinc |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Total number of polymer chains | 2 |
Total formula weight | 93370.37 |
Authors | Hovlid, M.L.,Edelstein, R.L.,Henry, O.,Ochocki, J.,DeGraw, A.,Lenevich, S.,Talbot, T.,Young, V.,Hruza, A.W.,Lopez-Gallego, F.,Labello, N.P.,Strickland, C.L.,Schmidt-Dannert, C.,Distefano, M.D. (deposition date: 2009-11-23, release date: 2009-12-22, Last modification date: 2023-09-06) |
Primary citation | Hovlid, M.L.,Edelstein, R.L.,Henry, O.,Ochocki, J.,DeGraw, A.,Lenevich, S.,Talbot, T.,Young, V.G.,Hruza, A.W.,Lopez-Gallego, F.,Labello, N.P.,Strickland, C.L.,Schmidt-Dannert, C.,Distefano, M.D. Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability. Chem.Biol.Drug Des., 75:51-67, 2010 Cited by PubMed: 19954434DOI: 10.1111/j.1747-0285.2009.00914.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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