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3KSL

Structure of FPT bound to DATFP-DH-GPP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Farnesyltransferase, CAAX box, alphapolymer37744086.11UniProt (Q5RKJ4)
Pfam (PF01239)
UniProt (by SIFTS) (Q04631)
Rattus norvegicus (brown rat rat rats)
2B
(B)
Protein farnesyltransferase subunit betapolymer43748722.31UniProt (Q02293)
Pfam (PF00432)
Rattus norvegicus (brown rat rat rats)FTase-beta, CAAX farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta
3C
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(B)
ZINC IONnon-polymer65.41Chemie (ZN)
5E
(B)
(2S,6E)-8-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}-2,6-dimethyloct-6-en-1-yl (2S)-3,3,3-trifluoro-2-hydrazinopropanoatenon-polymer472.31Chemie (SZH)
6F, G
(A, B)
waterwater18.0427Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight92808.4
Non-Polymers*Number of molecules3
Total formula weight562.0
All*Total formula weight93370.4
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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