5JT2
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![BU of 5jt2 by Molmil](/molmil-images/mine/5jt2) | BRAFV600E Kinase Domain In Complex with Chemically Linked Vemurafenib Inhibitor VEM-BISAMIDE | Descriptor: | 2,2'-oxybis(N-{[4-(3-{2,6-difluoro-3-[(propane-1-sulfonyl)amino]benzoyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]methyl}acetamide), BENZAMIDINE, Serine/threonine-protein kinase B-raf | Authors: | Grasso, M.J, Marmorstein, R. | Deposit date: | 2016-05-09 | Release date: | 2016-09-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAF(V600E) Conformation. Acs Chem.Biol., 11, 2016
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6TTR
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![BU of 6ttr by Molmil](/molmil-images/mine/6ttr) | Crystal Structure of the coiled coil and GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), GGDEF diguanylate cyclase DgcB, PHOSPHATE ION | Authors: | Holzschuh, F, Schirmer, T, Teixeira, R.D. | Deposit date: | 2019-12-30 | Release date: | 2021-01-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of the coiled coil and GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP To Be Published
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6TTS
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![BU of 6tts by Molmil](/molmil-images/mine/6tts) | Crystal structure of the GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), GGDEF diguanylate cyclase DgcB, SULFATE ION | Authors: | Holzschuh, F, Schirmer, T, Teixeira, R. | Deposit date: | 2019-12-30 | Release date: | 2021-01-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP To Be Published
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7RB3
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![BU of 7rb3 by Molmil](/molmil-images/mine/7rb3) | |
6UIA
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![BU of 6uia by Molmil](/molmil-images/mine/6uia) | |
8G0L
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![BU of 8g0l by Molmil](/molmil-images/mine/8g0l) | |
4PZR
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![BU of 4pzr by Molmil](/molmil-images/mine/4pzr) | |
4PZS
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![BU of 4pzs by Molmil](/molmil-images/mine/4pzs) | |
4KVO
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![BU of 4kvo by Molmil](/molmil-images/mine/4kvo) | |
4KVM
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![BU of 4kvm by Molmil](/molmil-images/mine/4kvm) | |
4R5K
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![BU of 4r5k by Molmil](/molmil-images/mine/4r5k) | Crystal structure of the DnaK C-terminus (Dnak-SBD-B) | Descriptor: | CALCIUM ION, Chaperone protein DnaK, SULFATE ION | Authors: | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | Deposit date: | 2014-08-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7469 Å) | Cite: | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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5SZR
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![BU of 5szr by Molmil](/molmil-images/mine/5szr) | Protocadherin Gamma B2 extracellular cadherin domains 3-6 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Goodman, K.M, Mannepalli, S, Bahna, F, Rubinstein, R, Honig, B, Shapiro, L. | Deposit date: | 2016-08-14 | Release date: | 2016-10-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | gamma-Protocadherin structural diversity and functional implications. Elife, 5, 2016
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4R5J
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![BU of 4r5j by Molmil](/molmil-images/mine/4r5j) | Crystal structure of the DnaK C-terminus (Dnak-SBD-A) | Descriptor: | CALCIUM ION, Chaperone protein DnaK, PHOSPHATE ION | Authors: | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | Deposit date: | 2014-08-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.361 Å) | Cite: | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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5FM4
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![BU of 5fm4 by Molmil](/molmil-images/mine/5fm4) | |
4R5G
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![BU of 4r5g by Molmil](/molmil-images/mine/4r5g) | Crystal structure of the DnaK C-terminus with the inhibitor PET-16 | Descriptor: | Chaperone protein DnaK, triphenyl(phenylethynyl)phosphonium | Authors: | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | Deposit date: | 2014-08-21 | Release date: | 2014-09-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.4501 Å) | Cite: | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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4R5I
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![BU of 4r5i by Molmil](/molmil-images/mine/4r5i) | Crystal structure of the DnaK C-terminus with the substrate peptide NRLLLTG | Descriptor: | Chaperone protein DnaK, HSP70/DnaK Substrate Peptide: NRLLLTG, PHOSPHATE ION, ... | Authors: | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | Deposit date: | 2014-08-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9702 Å) | Cite: | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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7KD7
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![BU of 7kd7 by Molmil](/molmil-images/mine/7kd7) | |
7KPU
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![BU of 7kpu by Molmil](/molmil-images/mine/7kpu) | |
4ZPO
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![BU of 4zpo by Molmil](/molmil-images/mine/4zpo) | Crystal Structure of Protocadherin Gamma C5 EC1-3 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, MCG133388, ... | Authors: | Wolcott, H.N, Goodman, K.M, Bahna, F, Mannepalli, S, Rubinstein, R, Honig, B, Shapiro, L. | Deposit date: | 2015-05-08 | Release date: | 2015-10-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions. Cell, 163, 2015
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4KVX
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![BU of 4kvx by Molmil](/molmil-images/mine/4kvx) | Crystal structure of Naa10 (Ard1) bound to AcCoA | Descriptor: | ACETYL COENZYME *A, N-terminal acetyltransferase A complex catalytic subunit ard1 | Authors: | Liszczak, G.P, Marmorstein, R.Q. | Deposit date: | 2013-05-23 | Release date: | 2013-07-31 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for N-terminal acetylation by the heterodimeric NatA complex. Nat.Struct.Mol.Biol., 20, 2013
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8RWK
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![BU of 8rwk by Molmil](/molmil-images/mine/8rwk) | cryoEM structure of the central Ald4 filament determined by FilamentID | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium-activated aldehyde dehydrogenase, mitochondrial | Authors: | Hugener, J, Xu, J, Wettstein, R, Ioannidi, L, Velikov, D, Wollweber, F, Henggeler, A, Matos, J, Pilhofer, M. | Deposit date: | 2024-02-05 | Release date: | 2024-06-26 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis. Cell, 187, 2024
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1XGV
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![BU of 1xgv by Molmil](/molmil-images/mine/1xgv) | Isocitrate Dehydrogenase from the hyperthermophile Aeropyrum pernix | Descriptor: | Isocitrate dehydrogenase | Authors: | Karlstrom, M, Stokke, R, Steen, I.H, Birkeland, N.-K, Ladenstein, R. | Deposit date: | 2004-09-17 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability J.Mol.Biol., 345, 2005
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7LJ9
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![BU of 7lj9 by Molmil](/molmil-images/mine/7lj9) | |
1ZX2
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![BU of 1zx2 by Molmil](/molmil-images/mine/1zx2) | Crystal Structure of Yeast UBP3-associated Protein BRE5 | Descriptor: | UBP3-associated protein BRE5 | Authors: | Li, K, Zhao, K, Ossareh-Nazari, B, Da, G, Dargemont, C, Marmorstein, R. | Deposit date: | 2005-06-06 | Release date: | 2005-06-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for interaction between the Ubp3 deubiquitinating enzyme and its Bre5 cofactor J.Biol.Chem., 280, 2005
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3ZFW
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![BU of 3zfw by Molmil](/molmil-images/mine/3zfw) | Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide | Descriptor: | KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 | Authors: | Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P. | Deposit date: | 2012-12-12 | Release date: | 2013-04-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Kinesin-1:Cargo Recognition. Science, 340, 2013
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