Crystal structure of p300 histone acetyltransferase domain in complex with Coenzyme A

Summary for 4PZR

Related4PZS 4PZT
DescriptorHistone acetyltransferase p300, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywordstransferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q09472
Total number of polymer chains1
Total molecular weight44759.6
Maksimoska, J.,Marmorstein, R. (deposition date: 2014-03-31, release date: 2014-06-11, Last modification date: 2014-06-25)
Primary citation
Maksimoska, J.,Segura-Pena, D.,Cole, P.A.,Marmorstein, R.
Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues.
Biochemistry, 53:3415-3422, 2014
PubMed: 24819397 (PDB entries with the same primary citation)
DOI: 10.1021/bi500380f
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.220902.0%5.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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