4BGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bgm by Molmil](/molmil-images/mine/4bgm) | Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 3-Carboxy-N-(2-fluoroethyl)-N,N-dimethylpropan-1- aminium chloride | Descriptor: | 3-Carboxy-N-(2-fluoroethyl)-N,N-dimethylpropan-1-aminium, GAMMA-BUTYROBETAINE DIOXYGENASE, HEXANE-1,6-DIAMINE, ... | Authors: | Tars, K, Leitans, J, Kazaks, A. | Deposit date: | 2013-03-27 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem., 57, 2014
|
|
4BHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bhg by Molmil](/molmil-images/mine/4bhg) | Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 3-(1-Ethyl-1,1-dimethylhydrazin-1-ium-2-yl)propanoate | Descriptor: | 3-(1-Ethyl-1,1-dimethylhydrazin-1-ium-2-yl)propanoic acid, GAMMA-BUTYROBETAINE DIOXYGENASE, HEXANE-1,6-DIAMINE, ... | Authors: | Tars, K, Leitans, J, Kazaks, A. | Deposit date: | 2013-04-02 | Release date: | 2014-04-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1-Ethyl-1,1-Dimethylhydrazin-1-Ium-2-Yl)Propanoate To be Published
|
|
4Z22
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z22 by Molmil](/molmil-images/mine/4z22) | structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor DR718A | Descriptor: | 2-amino-7-phenyl-3-{[(2R,5S)-5-phenyltetrahydrofuran-2-yl]methyl}quinazolin-4(3H)-one, Plasmepsin-2 | Authors: | Recacha, R, Leitans, J, Tars, K, Jaudzems, K. | Deposit date: | 2015-03-28 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV. J.Med.Chem., 59, 2016
|
|
6R1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r1g by Molmil](/molmil-images/mine/6r1g) | Crystal structure of Borrelia burgdorferi periplasmic protein BB0365 (IPLA7, p22) | Descriptor: | Outer surface 22 kDa lipoprotein, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | Authors: | Brangulis, K, Akopjana, I, Petrovskis, I, Kazaks, A, Tars, K. | Deposit date: | 2019-03-14 | Release date: | 2019-09-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural analysis of Borrelia burgdorferi periplasmic lipoprotein BB0365 involved in Lyme disease infection. Febs Lett., 594, 2020
|
|
6QO1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qo1 by Molmil](/molmil-images/mine/6qo1) | Crystal structure of Borrelia (Borreliella) burgdorferi outer surface protein BBA69 | Descriptor: | Putative surface protein | Authors: | Brangulis, K, Akopjana, I, Petrovskis, I, Kazaks, A, Tars, K. | Deposit date: | 2019-02-12 | Release date: | 2019-06-26 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of Borrelia burgdorferi outer surface protein BBA69 in comparison to the paralogous protein CspA. Ticks Tick Borne Dis, 10, 2019
|
|
4L8H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l8h by Molmil](/molmil-images/mine/4l8h) | |
6QUT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qut by Molmil](/molmil-images/mine/6qut) | |
6QN2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qn2 by Molmil](/molmil-images/mine/6qn2) | |
6QNG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qng by Molmil](/molmil-images/mine/6qng) | |
6QN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qn0 by Molmil](/molmil-images/mine/6qn0) | |
1X27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x27 by Molmil](/molmil-images/mine/1x27) | Crystal Structure of Lck SH2-SH3 with SH2 binding site of p130Cas | Descriptor: | CRK-associated substrate, Proto-oncogene tyrosine-protein kinase LCK, SODIUM ION | Authors: | Nasertorabi, F, Tars, K, Becherer, K, Kodandapani, R, Liljas, L, Vuori, K, Ely, K.R. | Deposit date: | 2005-04-20 | Release date: | 2006-02-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular basis for regulation of Src by the docking protein p130Cas J.MOL.RECOG., 19, 2006
|
|
6QN6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qn6 by Molmil](/molmil-images/mine/6qn6) | |
6QN5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qn5 by Molmil](/molmil-images/mine/6qn5) | |
6QNL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qnl by Molmil](/molmil-images/mine/6qnl) | |
4Y6M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y6m by Molmil](/molmil-images/mine/4y6m) | Structure of plasmepsin II from Plasmodium falciparum complexed with inhibitor PG418 | Descriptor: | GLYCEROL, Plasmepsin-2, ~{N}1-[(~{Z},3~{R})-4-[2-(3-methoxyphenyl)propan-2-ylamino]-3-oxidanyl-1-phenyl-but-1-en-2-yl]-5-piperidin-1-yl-~{N}3,~{N}3-dipropyl-benzene-1,3-dicarboxamide | Authors: | Recacha, R, Akopjana, I, Tars, K, Jaudzems, K. | Deposit date: | 2015-02-13 | Release date: | 2015-12-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors. Acta Crystallogr.,Sect.F, 71, 2015
|
|
5JOD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jod by Molmil](/molmil-images/mine/5jod) | Structure of proplasmepsin IV from Plasmodium falciparum | Descriptor: | GLYCEROL, Proplasmepsin IV | Authors: | Recacha, R, Akopjana, I, Tars, K, Jaudzems, K. | Deposit date: | 2016-05-02 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.528 Å) | Cite: | Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins. Acta Crystallogr.,Sect.F, 72, 2016
|
|
5JXV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jxv by Molmil](/molmil-images/mine/5jxv) | Solid-state MAS NMR structure of immunoglobulin beta 1 binding domain of protein G (GB1) | Descriptor: | Immunoglobulin G-binding protein G | Authors: | Andreas, L.B, Jaudzems, K, Stanek, J, Lalli, D, Bertarello, A, Le Marchand, T, Cala-De Paepe, D, Kotelovica, S, Akopjana, I, Knott, B, Wegner, S, Engelke, F, Lesage, A, Emsley, L, Tars, K, Herrmann, T, Pintacuda, G. | Deposit date: | 2016-05-13 | Release date: | 2016-08-10 | Last modified: | 2024-06-19 | Method: | SOLID-STATE NMR | Cite: | Structure of fully protonated proteins by proton-detected magic-angle spinning NMR. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5JZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jzr by Molmil](/molmil-images/mine/5jzr) | Solid-state MAS NMR structure of Acinetobacter phage 205 (AP205) coat protein in assembled capsid particles | Descriptor: | Coat protein | Authors: | Jaudzems, K, Andreas, L.B, Stanek, J, Lalli, D, Bertarello, A, Le Marchand, T, Cala-De Paepe, D, Kotelovica, S, Akopjana, I, Knott, B, Wegner, S, Engelke, F, Lesage, A, Emsley, L, Tars, K, Herrmann, T, Pintacuda, G. | Deposit date: | 2016-05-17 | Release date: | 2016-08-10 | Last modified: | 2024-06-19 | Method: | SOLID-STATE NMR | Cite: | Structure of fully protonated proteins by proton-detected magic-angle spinning NMR. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4YA8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ya8 by Molmil](/molmil-images/mine/4ya8) | structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor PG394 | Descriptor: | GLYCEROL, N'-[(2S,3S)-3-hydroxy-1-phenyl-4-{[2-(pyridin-2-yl)propan-2-yl]amino}butan-2-yl]-N,N-dipropyl-5-(pyridin-1(2H)-yl)benzene-1,3-dicarboxamide, Plasmepsin-2 | Authors: | Recacha, R, Leitans, J, Tars, K, Jaudzems, K. | Deposit date: | 2015-02-17 | Release date: | 2015-12-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.301 Å) | Cite: | Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors. Acta Crystallogr.,Sect.F, 71, 2015
|
|
5LQP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lqp by Molmil](/molmil-images/mine/5lqp) | |
1FR5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fr5 by Molmil](/molmil-images/mine/1fr5) | PHAGE FR CAPSIDS WITH A FOUR RESIDUE DELETION IN THE COAT PROTEIN FG LOOP | Descriptor: | BACTERIOPHAGE FR CAPSID | Authors: | Axblom, C, Tars, K, Fridborg, K, Bundule, M, Orna, L, Liljas, L. | Deposit date: | 1998-07-22 | Release date: | 1999-01-13 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of phage fr capsids with a deletion in the FG loop: implications for viral assembly. Virology, 249, 1998
|
|
6HPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hpn by Molmil](/molmil-images/mine/6hpn) | Crystal structure of Borrelia spielmanii WP_012665240 (BSA64) - an orthologous protein to B. burgdorferi BBA64 | Descriptor: | Antigen, P35 | Authors: | Brangulis, K, Akopjana, I, Kazaks, A, Tars, K. | Deposit date: | 2018-09-21 | Release date: | 2019-10-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural analysis of the outer surface proteins from Borrelia burgdorferi paralogous gene family 54 that are thought to be the key players in the pathogenesis of Lyme disease. J.Struct.Biol., 210, 2020
|
|
5FS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fs4 by Molmil](/molmil-images/mine/5fs4) | Bacteriophage AP205 coat protein | Descriptor: | AP205 BACTERIOPHAGE COAT PROTEIN | Authors: | Shishovs, M, Tars, K. | Deposit date: | 2015-12-29 | Release date: | 2016-09-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structure of Ap205 Coat Protein Reveals Circular Permutation in Ssrna Bacteriophages. J.Mol.Biol., 428, 2016
|
|
8CQO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cqo by Molmil](/molmil-images/mine/8cqo) | Crystal structure of Borrelia burgdorferi paralogous family 12 outer surface protein BBK01 (Se-Met data) | Descriptor: | Lipoprotein, putative | Authors: | Brangulis, K, Drunka, L, Matisone, S, Akopjana, I, Tars, K. | Deposit date: | 2023-03-06 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of Borrelia burgdorferi outer surface protein BBK01 To Be Published
|
|
8CQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cqn by Molmil](/molmil-images/mine/8cqn) | Crystal structure of Borrelia burgdorferi paralogous family 12 outer surface protein BBK01 | Descriptor: | Lipoprotein, putative | Authors: | Brangulis, K, Drunka, L, Matisone, S, Akopjana, I, Tars, K. | Deposit date: | 2023-03-06 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of Borrelia burgdorferi outer surface protein BBK01 To Be Published
|
|