6J14
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![BU of 6j14 by Molmil](/molmil-images/mine/6j14) | Complex structure of GY-14 and PD-1 | 分子名称: | GY-14 heavy chain V fragment, GY-14 light chain V fragment, Programmed cell death protein 1 | 著者 | Chen, D, Tan, S, Whang, H, Zhang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | 登録日 | 2018-12-27 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy. Iscience, 14, 2019
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8I5D
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![BU of 8i5d by Molmil](/molmil-images/mine/8i5d) | Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) | 分子名称: | Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ... | 著者 | Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F. | 登録日 | 2023-01-25 | 公開日 | 2023-08-23 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) Nat Commun, 2023
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6JBT
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![BU of 6jbt by Molmil](/molmil-images/mine/6jbt) | Complex structure of toripalimab-Fab and PD-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, ... | 著者 | Guo, L, Tan, S, Chai, Y, Qi, J, Gao, G.F, Yan, J. | 登録日 | 2019-01-26 | 公開日 | 2019-06-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Glycosylation-independent binding of monoclonal antibody toripalimab to FG loop of PD-1 for tumor immune checkpoint therapy. Mabs, 11, 2019
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6J15
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![BU of 6j15 by Molmil](/molmil-images/mine/6j15) | Complex structure of GY-5 Fab and PD-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GY-5 heavy chain Fab, ... | 著者 | Chen, D, Tan, S, Zhang, H, Wang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | 登録日 | 2018-12-27 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy. Iscience, 14, 2019
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8I5E
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![BU of 8i5e by Molmil](/molmil-images/mine/8i5e) | Crystal structure of HLA-A*11:01 in complex with KRAS peptide (VVGAGGVGK) | 分子名称: | Beta-2-microglobulin, KRAS-G12wt-9, MHC class I antigen (Fragment) | 著者 | Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F. | 登録日 | 2023-01-25 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) Nat Commun, 2023
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5HQ2
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![BU of 5hq2 by Molmil](/molmil-images/mine/5hq2) | Structural model of Set8 histone H4 Lys20 methyltransferase bound to nucleosome core particle | 分子名称: | DNA (149-MER), Guanine nucleotide exchange factor SRM1, Histone H2A, ... | 著者 | Tavarekere, G, McGinty, R.K, Tan, S. | 登録日 | 2016-01-21 | 公開日 | 2016-03-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate. J.Mol.Biol., 428, 2016
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8YTI
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![BU of 8yti by Molmil](/molmil-images/mine/8yti) | Crystal Structure of Nucleosome-H1x Linker Histone Assembly (sticky-169a DNA fragment) | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (169-MER), ... | 著者 | Adhireksan, Z, Qiuye, B, Padavattan, S, Davey, C.A. | 登録日 | 2024-03-26 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Linker Histones Associate Heterogeneously with Nucleosomes in the Condensed State To Be Published
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8YIB
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![BU of 8yib by Molmil](/molmil-images/mine/8yib) | Staphylococcus aureus lipase -PSA complex - covalent bonding state | 分子名称: | ACETIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Kitadokoro, J, Kamitani, S, Kitadokoro, K. | 登録日 | 2024-02-29 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Crystal structure of Staphylococcus aureus lipase complex with unsaturated petroselinic acid. Febs Open Bio, 14, 2024
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8GVB
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![BU of 8gvb by Molmil](/molmil-images/mine/8gvb) | The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 peptide | 分子名称: | 8-mer peptide from Protein Nef, Beta-2-microglobulin, MHC class I antigen, ... | 著者 | Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A. | 登録日 | 2022-09-14 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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3VND
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![BU of 3vnd by Molmil](/molmil-images/mine/3vnd) | Crystal structure of tryptophan synthase alpha-subunit from the psychrophile Shewanella frigidimarina K14-2 | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SULFATE ION, Tryptophan synthase alpha chain | 著者 | Mitsuya, D, Tanaka, S, Matsumura, H, Takano, K, Urano, N, Ishida, M. | 登録日 | 2012-01-12 | 公開日 | 2013-01-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Strategy for cold adaptation of the tryptophan synthase alpha subunit from the psychrophile Shewanella frigidimarina K14-2: crystal structure and physicochemical properties J.Biochem., 155, 2014
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8GVG
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![BU of 8gvg by Molmil](/molmil-images/mine/8gvg) | The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 (2F) peptide | 分子名称: | Beta-2-microglobulin, MHC class I antigen, TD08 TCR alpha chain, ... | 著者 | Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A. | 登録日 | 2022-09-15 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | 主引用文献 | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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8GVI
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![BU of 8gvi by Molmil](/molmil-images/mine/8gvi) | The complex between H25-11 TCR and HLA-A24 bound to HIV-1 Nef138-8 peptide | 分子名称: | 8-mer peptide from Protein Nef, Beta-2-microglobulin, H25-11 TCR alpha chain, ... | 著者 | Gao, G.F, Shi, Y, Tan, S, Ma, K, Chai, Y, Qi, J, Kawana-Tachikawa, A, Iwamoto, A, Dong, T, Guan, J. | 登録日 | 2022-09-15 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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5XJ3
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![BU of 5xj3 by Molmil](/molmil-images/mine/5xj3) | Complex structure of ipilimumab-scFv and CTLA-4 | 分子名称: | Cytotoxic T-lymphocyte protein 4, ipilimumab-VH, ipilimumab-VL | 著者 | He, M, Chai, Y, Qi, J, Tong, Z, Tan, S, Gao, G.F. | 登録日 | 2017-04-29 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies Oncotarget, 8, 2017
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2LKE
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![BU of 2lke by Molmil](/molmil-images/mine/2lke) | Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails | 分子名称: | Integrin alpha-M | 著者 | Chua, G.L, Tang, X.Y, Amalraj, M, Bhattacharjya, S, Tan, S.M. | 登録日 | 2011-10-11 | 公開日 | 2011-11-02 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails J.Biol.Chem., 2011
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2LKJ
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![BU of 2lkj by Molmil](/molmil-images/mine/2lkj) | Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails | 分子名称: | Integrin alpha-M | 著者 | Chua, G.L, Tang, X.Y, Amalraj, M, Tan, S.M, Bhattacharjya, S. | 登録日 | 2011-10-12 | 公開日 | 2011-11-02 | 最終更新日 | 2011-11-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails J.Biol.Chem., 2011
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6CW3
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![BU of 6cw3 by Molmil](/molmil-images/mine/6cw3) | Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 2 | 分子名称: | Histone acetyltransferase GCN5, Transcriptional adapter 2, ZINC ION, ... | 著者 | Sun, J, Paduch, M, Kim, S.A, Kramer, R.M, Barrios, A.F, Lu, V, Luke, J, Usatyuk, S, Kossiakoff, A.A, Tan, S. | 登録日 | 2018-03-29 | 公開日 | 2018-09-19 | 最終更新日 | 2020-03-04 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3MVD
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![BU of 3mvd by Molmil](/molmil-images/mine/3mvd) | Crystal structure of the chromatin factor RCC1 in complex with the nucleosome core particle | 分子名称: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Makde, R.D, England, J.R, Yennawar, H.P, Tan, S. | 登録日 | 2010-05-04 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of RCC1 chromatin factor bound to the nucleosome core particle. Nature, 467, 2010
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4HX1
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![BU of 4hx1 by Molmil](/molmil-images/mine/4hx1) | Structure of HLA-A68 complexed with a tumor antigen derived peptide | 分子名称: | 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2012-11-09 | 公開日 | 2013-10-02 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
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4I48
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![BU of 4i48 by Molmil](/molmil-images/mine/4i48) | Structure of HLA-A68 complexed with an HIV Env derived peptide | 分子名称: | 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2012-11-27 | 公開日 | 2013-10-02 | 実験手法 | X-RAY DIFFRACTION (2.799 Å) | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
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4HWZ
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![BU of 4hwz by Molmil](/molmil-images/mine/4hwz) | Structure of HLA-A68 complexed with an HIV derived peptide | 分子名称: | 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2012-11-09 | 公開日 | 2013-10-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
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2K8O
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![BU of 2k8o by Molmil](/molmil-images/mine/2k8o) | |
4JZG
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![BU of 4jzg by Molmil](/molmil-images/mine/4jzg) | Crystal structure of a single cambialistic SOD2 occupied by Manganese ion from Clostridium difficile | 分子名称: | MANGANESE (II) ION, Superoxide dismutase | 著者 | Li, W, Wang, C.L, Zhao, Y, Wang, H.F, Tan, S.X. | 登録日 | 2013-04-02 | 公開日 | 2014-04-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.321 Å) | 主引用文献 | Crystal structure of a single cambialistic SOD2 occupied by Manganese ion from Clostridium difficile To be Published
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4N37
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![BU of 4n37 by Molmil](/molmil-images/mine/4n37) | Structure of langerin CRD I313 D288 complexed with Me-Man | 分子名称: | C-type lectin domain family 4 member K, CALCIUM ION, methyl alpha-D-mannopyranoside | 著者 | Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E. | 登録日 | 2013-10-06 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Common polymorphisms in human langerin change specificity for glycan ligands. J.Biol.Chem., 288, 2013
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4N38
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![BU of 4n38 by Molmil](/molmil-images/mine/4n38) | Structure of langerin CRD I313 D288 complexed with GlcNAc-beta1-3Gal-beta1-4GlcNAc-beta-CH2CH2N3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, C-type lectin domain family 4 member K, CALCIUM ION, ... | 著者 | Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E. | 登録日 | 2013-10-06 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Common polymorphisms in human langerin change specificity for glycan ligands. J.Biol.Chem., 288, 2013
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4N35
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![BU of 4n35 by Molmil](/molmil-images/mine/4n35) | Structure of langerin CRD I313 complexed with GlcNAc-beta1-3Gal-beta1-4Glc-beta-CH2CH2N3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, C-type lectin domain family 4 member K, ... | 著者 | Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E. | 登録日 | 2013-10-06 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Common polymorphisms in human langerin change specificity for glycan ligands. J.Biol.Chem., 288, 2013
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