1PWM
| Crystal structure of human Aldose Reductase complexed with NADP and Fidarestat | 分子名称: | (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | El-Kabbani, O, Darmanin, C, Schneider, T.R, Hazemann, I, Ruiz, F, Oka, M, Joachimiak, A, Schulze-Briese, C, Tomizaki, T, Mitschler, A, Podjarny, A. | 登録日 | 2003-07-02 | 公開日 | 2004-02-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | 主引用文献 | Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors PROTEINS, 55, 2004
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1UPD
| Oxidized STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6 | 分子名称: | CYTOCHROME C3, HEME C | 著者 | Bento, I, Matias, P.M, Baptista, A.M, Da Costa, P.N, Van Dongen, W.M.A.M, Saraiva, L.M, Schneider, T.R, Soares, C.M, Carrondo, M.A. | 登録日 | 2003-09-29 | 公開日 | 2004-09-30 | 最終更新日 | 2019-05-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6 Proteins, 54, 2004
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1SYC
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1T45
| STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE | 分子名称: | Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 著者 | Mol, C.D, Dougan, D.R, Schneider, T.R, Skene, R.J, Kraus, M.L, Scheibe, D.N, Snell, G.P, Zou, H, Sang, B.C, Wilson, K.P. | 登録日 | 2004-04-28 | 公開日 | 2004-06-15 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase. J.Biol.Chem., 279, 2004
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1UP9
| REDUCED STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6 | 分子名称: | CYTOCHROME C3, HEME C, SULFATE ION | 著者 | Bento, I, Matias, P.M, Baptista, A.M, Da Costa, P.N, Van Dongen, W.M.A.M, Saraiva, L.M, Schneider, T.R, Soares, C.M, Carrondo, M.A. | 登録日 | 2003-09-29 | 公開日 | 2004-09-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6 Proteins, 54, 2004
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1US0
| Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom | 分子名称: | ALDOSE REDUCTASE, CITRIC ACID, IDD594, ... | 著者 | Howard, E.I, Sanishvili, R, Cachau, R.E, Mitschler, A, Chevrier, B, Barth, P, Lamour, V, Van Zandt, M, Sibley, E, Bon, C, Moras, D, Schneider, T.R, Joachimiak, A, Podjarny, A. | 登録日 | 2003-11-16 | 公開日 | 2004-05-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (0.66 Å) | 主引用文献 | Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A. Proteins, 55, 2004
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1TUT
| J4/5 Loop from the Candida albicans and Candida dubliniensis Group I Introns | 分子名称: | 5'-R(*GP*AP*GP*GP*AP*AP*GP*GP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*UP*AP*AP*UP*CP*UP*C)-3' | 著者 | Znosko, B.M, Kennedy, S.D, Wille, P.C, Krugh, T.R, Turner, D.H. | 登録日 | 2004-06-25 | 公開日 | 2004-12-28 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Features and Thermodynamics of the J4/5 Loop from the Candida albicans and Candida dubliniensis Group I Introns. Biochemistry, 43, 2004
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1TZ7
| Aquifex aeolicus amylomaltase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-alpha-glucanotransferase | 著者 | Barends, T.R.M, Korf, H, Kaper, T, van der Maarel, M.J.E.C, Dijkhuizen, L, Dijkstra, B.W. | 登録日 | 2004-07-09 | 公開日 | 2005-08-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural influences on product specificity in amylomaltase from Aquifex aeolicus TO BE PUBLISHED
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1SYG
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1VIB
| NMR SOLUTION STRUCTURE OF THE NEUROTOXIN B-IV, 20 STRUCTURES | 分子名称: | NEUROTOXIN B-IV | 著者 | Barnham, K.J, Dyke, T.R, Kem, W.R, Norton, R.S. | 登録日 | 1996-11-25 | 公開日 | 1997-05-15 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of neurotoxin B-IV from the marine worm Cerebratulus lacteus: a helical hairpin cross-linked by disulphide bonding. J.Mol.Biol., 268, 1997
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1TH1
| Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment | 分子名称: | Adenomatous polyposis coli protein, Beta-catenin | 著者 | Xing, Y, Clements, W.K, Le Trong, I, Hinds, T.R, Stenkamp, R, Kimelman, D, Xu, W. | 登録日 | 2004-05-31 | 公開日 | 2004-09-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of a beta-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function. Mol.Cell, 15, 2004
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1QOW
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1SYD
| ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE | 分子名称: | CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE | 著者 | Hynes, T.R, Hodel, A, Fox, R.O. | 登録日 | 1994-01-07 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Engineering alternative beta-turn types in staphylococcal nuclease. Biochemistry, 33, 1994
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1VRX
| Endocellulase e1 from acidothermus cellulolyticus mutant y245g | 分子名称: | ENDOCELLULASE E1 FROM A. CELLULOLYTICUS | 著者 | Baker, J.O, McCarley, J.R, Lovett, R, Yu, C.H, Adney, W.S, Rignall, T.R, Vinzant, T.B, Decker, S.R, Sakon, J, Himmel, M.E. | 登録日 | 2005-06-30 | 公開日 | 2005-07-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Catalytically enhanced endocellulase Cel5A from Acidothermus cellulolyticus. Appl.Biochem.Biotechnol., 121-124, 2005
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1OF8
| double complex of the tyrosine sensitive DAHP Synthase from S. cerevisiae with Co2+, PEP and the E4P analogoue G3P | 分子名称: | COBALT (II) ION, GLYCEROL, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, ... | 著者 | Koenig, V, Pfeil, A, Heinrich, G, Braus, G.H, Schneider, T.R. | 登録日 | 2003-04-08 | 公開日 | 2004-04-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism J.Mol.Biol., 337, 2004
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1QZG
| Crystal structure of Pot1 (protection of telomere)- ssDNA complex | 分子名称: | Protection of telomeres protein 1, THYMIDINE-5'-PHOSPHATE, telomeric single-stranded DNA | 著者 | Lei, M, Podell, E.R, Baumann, P, Cech, T.R. | 登録日 | 2003-09-16 | 公開日 | 2003-11-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA Nature, 426, 2003
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1R0Q
| Characterization of the conversion of the malformed, recombinant cytochrome rc552 to a 2-formyl-4-vinyl (Spirographis) heme | 分子名称: | 2-FORMYL-PROTOPORPHRYN IX, Cytochrome c-552 | 著者 | Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. | 登録日 | 2003-09-22 | 公開日 | 2004-09-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry, 43, 2004
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1QXM
| Crystal structure of a hemagglutinin component (HA1) from type C Clostridium botulinum | 分子名称: | 1,2-ETHANEDIOL, HA1 | 著者 | Inoue, K, Sobhany, M, Transue, T.R, Oguma, K, Pedersen, L.C, Negishi, M. | 登録日 | 2003-09-08 | 公開日 | 2004-01-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural analysis by X-ray crystallography and calorimetry of a haemagglutinin component (HA1) of the progenitor toxin from Clostridium botulinum. Microbiology, 149, 2003
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1QZH
| Crystal structure of Pot1 (protection of telomere)- ssDNA complex | 分子名称: | Protection of telomeres protein 1, telomeric single-stranded DNA | 著者 | Lei, M, Podell, E.R, Baumann, P, Cech, T.R. | 登録日 | 2003-09-16 | 公開日 | 2003-11-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA Nature, 426, 2003
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1QYZ
| Characterization of the malformed, recombinant cytochrome rC552 | 分子名称: | 2-ACETYL-PROTOPORPHYRIN IX, Cytochrome c-552 | 著者 | Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. | 登録日 | 2003-09-12 | 公開日 | 2004-09-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry, 43, 2004
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7KZ7
| Crystals Structure of the Mutated Protease Domain of Botulinum Neurotoxin X (X4130B1). | 分子名称: | 1,2-ETHANEDIOL, Botulinum neurotoxin type X, GLYCEROL, ... | 著者 | Blum, T.R, Liu, H, Packer, M.S, Xiong, X, Lee, P.G, Zhang, S, Richter, M, Minasov, G, Satchell, K.J.F, Dong, M, Liu, D.R, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-12-10 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity. Science, 371, 2021
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7KY7
| Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the apo E1 state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkylphosphocholine resistance protein LEM3, CHOLESTEROL, ... | 著者 | Bai, L, You, Q, Jain, B.K, Duan, H.D, Kovach, A, Graham, T.R, Li, H. | 登録日 | 2020-12-07 | 公開日 | 2021-01-06 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Transport mechanism of P4 ATPase phosphatidylcholine flippases. Elife, 9, 2020
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8BY1
| streptavidin with an iridium catalyst for CH activation | 分子名称: | SULFATE ION, Streptavidin, tert-butyl 7'-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-1-chloranyl-2,3,4,5,6-pentamethyl-spiro[1$l^{8}-iridapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane-1,2'-3-aza-1-azonia-2$l^{8}-iridatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaene]-3'-carboxylate | 著者 | Igareta, N.V, Ward, T.R. | 登録日 | 2022-12-11 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.486 Å) | 主引用文献 | streptavidin mutant S112I with an iridium catalyst for CH activation To Be Published
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8BY0
| streptavidin mutant S112I K121R with an iridium catalyst for CH activation | 分子名称: | SULFATE ION, Streptavidin, tert-butyl 7'-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-1-chloranyl-2,3,4,5,6-pentamethyl-spiro[1$l^{8}-iridapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane-1,2'-3-aza-1-azonia-2$l^{8}-iridatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaene]-3'-carboxylate | 著者 | Igareta, N.V, Ward, T.R. | 登録日 | 2022-12-11 | 公開日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | streptavidin mutant S112I with an iridium catalyst for CH activation To Be Published
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8C24
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