7KZ7

Crystals Structure of the Mutated Protease Domain of Botulinum Neurotoxin X (X4130B1).

Summary for 7KZ7

Entry DOI	10.2210/pdb7kz7/pdb
Descriptor	Botulinum neurotoxin type X, ZINC ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	structural genomics, center for structural genomics of infectious diseases, csgid, neurotoxin x, protease domain, toxin
Biological source	Clostridium botulinum
Total number of polymer chains	1
Total formula weight	51464.28
Authors	Blum, T.R.,Liu, H.,Packer, M.S.,Xiong, X.,Lee, P.G.,Zhang, S.,Richter, M.,Minasov, G.,Satchell, K.J.F.,Dong, M.,Liu, D.R.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-12-10, release date: 2020-12-23, Last modification date: 2023-10-18)
Primary citation	Blum, T.R.,Liu, H.,Packer, M.S.,Xiong, X.,Lee, P.G.,Zhang, S.,Richter, M.,Minasov, G.,Satchell, K.J.F.,Dong, M.,Liu, D.R. Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity. Science, 371:803-810, 2021 Cited by PubMed: 33602850 DOI: 10.1126/science.abf5972 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation