7KZ7
Crystals Structure of the Mutated Protease Domain of Botulinum Neurotoxin X (X4130B1).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Botulinum neurotoxin type X | polymer | 445 | 50780.2 | 1 | UniProt (P0DPK1) Pfam (PF01742) | Clostridium botulinum | BoNT/X,Bontoxilysin-X |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | J, K (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | L (A) | water | water | 18.0 | 407 | Chemie (HOH) |
Sequence modifications
A: 1 - 439 (UniProt: P0DPK1)
| PDB | External Database | Details |
|---|---|---|
| Asp 143 | Asn 143 | engineered mutation |
| Thr 148 | Asn 148 | engineered mutation |
| Glu 166 | Ala 166 | engineered mutation |
| Ile 167 | Thr 167 | engineered mutation |
| Asn 314 | Tyr 314 | engineered mutation |
| Ile 364 | Leu 364 | engineered mutation |
| His 440 | - | expression tag |
| His 441 | - | expression tag |
| His 442 | - | expression tag |
| His 443 | - | expression tag |
| His 444 | - | expression tag |
| His 445 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50780.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 684.1 | |
| All* | Total formula weight | 51464.3 |
