5OBN
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![BU of 5obn by Molmil](/molmil-images/mine/5obn) | NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516) | Descriptor: | RNA-binding protein 40 | Authors: | Norppa, A.J, Kauppala, T.M, Heikkinen, H.A, Verma, B, Iwai, H, Frilander, M.J. | Deposit date: | 2017-06-28 | Release date: | 2018-01-24 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA. RNA, 24, 2018
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1MZC
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![BU of 1mzc by Molmil](/molmil-images/mine/1mzc) | Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate and Inhibitor Compound 33a | Descriptor: | 2-[3-(3-ETHYL-1-METHYL-2-OXO-AZEPAN-3-YL)-PHENOXY]-4-[1-AMINO-1-(1-METHYL-1H-IMIDIZOL-5-YL)-ETHYL]-BENZONITRILE, FARNESYL DIPHOSPHATE, Protein Farnesyltransferase alpha Subunit, ... | Authors: | deSolms, S.J, Ciccarone, T.M, MacTough, S.C, Shaw, A.W, Buser, C.A, Ellis-Hutchings, M, Fernandes, C, Hamilton, K.A, Huber, H.E, Kohl, N.E, Lobell, R.B, Robinson, R.G, Tsou, N.N, Walsh, E.S, Graham, S.L, Beese, L.S, Taylor, J.S. | Deposit date: | 2002-10-07 | Release date: | 2003-07-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dual Protein Farnesyltransferase-Geranylgeranyltransferase-I Inhibitors as Potential Cancer Chemotherapeutic Agents. J.Med.Chem., 46, 2003
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5OP6
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![BU of 5op6 by Molmil](/molmil-images/mine/5op6) | Factor Inhibiting HIF (FIH) in complex with zinc and GSK128863 | Descriptor: | 2-[[1,3-dicyclohexyl-4-oxidanyl-2,6-bis(oxidanylidene)pyrimidin-5-yl]carbonylamino]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Leissing, T.M, Schofield, C.J, Clifton, I.J, Thinnes, C.C, Lu, X. | Deposit date: | 2017-08-09 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials. Chem Sci, 8, 2017
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1N53
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![BU of 1n53 by Molmil](/molmil-images/mine/1n53) | SOLUTION STRUCTURE OF B. SUBTILIS T BOX ANTITERMINATOR RNA | Descriptor: | RNA (5'-R(*GP*AP*GP*GP*GP*UP*GP*GP*AP*AP*CP*CP*GP*CP*GP*C)-3'), RNA (5'-R(*GP*CP*GP*UP*CP*CP*CP*UP*C)-3') | Authors: | Gerdeman, M.S, Henkin, T.M, Hines, J.V. | Deposit date: | 2002-11-04 | Release date: | 2003-04-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Bacillus subtilis T-box Antiterminator RNA: Seven Nucleotide
Bulge Characterized by Stacking and Flexibility J.Mol.Biol., 326, 2003
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1QRE
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![BU of 1qre by Molmil](/molmil-images/mine/1qre) | A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA | Descriptor: | BICARBONATE ION, CARBONIC ANHYDRASE, COBALT (II) ION | Authors: | Iverson, T.M, Alber, B.E, Kisker, C, Ferry, J.G, Rees, D.C. | Deposit date: | 1999-06-13 | Release date: | 1999-06-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry, 39, 2000
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1QRL
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![BU of 1qrl by Molmil](/molmil-images/mine/1qrl) | A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA | Descriptor: | BICARBONATE ION, CARBONIC ANHYDRASE, ZINC ION | Authors: | Iverson, T.M, Alber, B.E, Kisker, C, Ferry, J.G, Rees, D.C. | Deposit date: | 1999-06-15 | Release date: | 1999-06-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry, 39, 2000
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5WI3
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![BU of 5wi3 by Molmil](/molmil-images/mine/5wi3) | Structure of Acinetobacter baumannii carbapenemase OXA-239 K82D bound to cefotaxime | Descriptor: | CEFOTAXIME, C3' cleaved, open, ... | Authors: | Harper, T.M, June, C.M, Powers, R.A, Leonard, D.A. | Deposit date: | 2017-07-18 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Multiple substitutions lead to increased loop flexibility and expanded specificity in Acinetobacter baumannii carbapenemase OXA-239. Biochem. J., 475, 2018
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1QVF
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![BU of 1qvf by Molmil](/molmil-images/mine/1qvf) | Structure of a deacylated tRNA minihelix bound to the E site of the large ribosomal subunit of Haloarcula marismortui | Descriptor: | 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ... | Authors: | Schmeing, T.M, Moore, P.B, Steitz, T.A. | Deposit date: | 2003-08-27 | Release date: | 2003-11-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit RNA, 9, 2003
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1QRF
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![BU of 1qrf by Molmil](/molmil-images/mine/1qrf) | A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA | Descriptor: | CARBONIC ANHYDRASE, COBALT (II) ION, SULFATE ION | Authors: | Iverson, T.M, Alber, B.E, Kisker, C, Ferry, J.G, Rees, D.C. | Deposit date: | 1999-06-13 | Release date: | 1999-06-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry, 39, 2000
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1QRM
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![BU of 1qrm by Molmil](/molmil-images/mine/1qrm) | A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA | Descriptor: | CARBONIC ANHYDRASE, SULFATE ION, ZINC ION | Authors: | Iverson, T.M, Alber, B.E, Kisker, C, Ferry, J.G, Rees, D.C. | Deposit date: | 1999-06-15 | Release date: | 1999-06-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry, 39, 2000
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1Q82
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![BU of 1q82 by Molmil](/molmil-images/mine/1q82) | Crystal Structure of CC-Puromycin bound to the A-site of the 50S ribosomal subunit | Descriptor: | 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ... | Authors: | Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. | Deposit date: | 2003-08-20 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Structural Insights Into Peptide Bond Formation Proc.Natl.Acad.Sci.USA, 99, 2002
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1QPG
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![BU of 1qpg by Molmil](/molmil-images/mine/1qpg) | 3-PHOSPHOGLYCERATE KINASE, MUTATION R65Q | Descriptor: | 3-PHOSPHOGLYCERATE KINASE, 3-PHOSPHOGLYCERIC ACID, MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE | Authors: | Mcphillips, T.M, Hsu, B.T, Sherman, M.A, Mas, M.T, Rees, D.C. | Deposit date: | 1996-01-04 | Release date: | 1996-06-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the R65Q mutant of yeast 3-phosphoglycerate kinase complexed with Mg-AMP-PNP and 3-phospho-D-glycerate. Biochemistry, 35, 1996
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1QQ0
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![BU of 1qq0 by Molmil](/molmil-images/mine/1qq0) | COBALT SUBSTITUTED CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA | Descriptor: | CARBONIC ANHYDRASE, COBALT (II) ION | Authors: | Iverson, T.M, Alber, B.E, Kisker, C, Ferry, J.G, Rees, D.C. | Deposit date: | 1999-06-10 | Release date: | 1999-06-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry, 39, 2000
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1Q7Y
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![BU of 1q7y by Molmil](/molmil-images/mine/1q7y) | Crystal Structure of CCdAP-Puromycin bound at the Peptidyl transferase center of the 50S ribosomal subunit | Descriptor: | 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ... | Authors: | Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. | Deposit date: | 2003-08-20 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Insights Into Peptide Bond Formation Proc.Natl.Acad.Sci.USA, 99, 2002
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1Q86
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![BU of 1q86 by Molmil](/molmil-images/mine/1q86) | Crystal structure of CCA-Phe-cap-biotin bound simultaneously at half occupancy to both the A-site and P-site of the the 50S ribosomal Subunit. | Descriptor: | 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ... | Authors: | Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. | Deposit date: | 2003-08-20 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into peptide bond formation. Proc.Natl.Acad.Sci.USA, 99, 2002
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1QBY
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![BU of 1qby by Molmil](/molmil-images/mine/1qby) | THE SOLUTION STRUCTURE OF A BAY-REGION 1R-BENZ[A]ANTHRACENE OXIDE ADDUCT AT THE N6 POSITION OF ADENINE OF AN OLIGODEOXYNUCLEOTIDE CONTAINING THE HUMAN N-RAS CODON 61 SEQUENCE | Descriptor: | 1R,2S,3R,4S-TETRAHYDRO-BENZO[A]ANTHRACENE-2,3,4-TRIOL, 5'-D(*CP*GP*GP*AP*CP*(BZA)AP*AP*GP*AP*AP*G)-3', 5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP* G)-3' | Authors: | Li, Z, Mao, H, Kim, H.-Y, Tamura, P.J, Harris, C.M, Harris, T.M, Stone, M.P. | Deposit date: | 1999-04-27 | Release date: | 1999-05-06 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Intercalation of the (-)-(1R,2S,3R, 4S)-N6-[1-benz[a]anthracenyl]-2'-deoxyadenosyl adduct in an oligodeoxynucleotide containing the human N-ras codon 61 sequence. Biochemistry, 38, 1999
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1QVG
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![BU of 1qvg by Molmil](/molmil-images/mine/1qvg) | Structure of CCA oligonucleotide bound to the tRNA binding sites of the large ribosomal subunit of Haloarcula marismortui | Descriptor: | 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ... | Authors: | Schmeing, T.M, Moore, P.B, Steitz, T.A. | Deposit date: | 2003-08-27 | Release date: | 2003-11-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit RNA, 9, 2003
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1Q81
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![BU of 1q81 by Molmil](/molmil-images/mine/1q81) | Crystal Structure of minihelix with 3' puromycin bound to A-site of the 50S ribosomal subunit. | Descriptor: | 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ... | Authors: | Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. | Deposit date: | 2003-08-20 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural Insights into Peptide Bond Formation Proc.Natl.Acad.Sci.USA, 99, 2002
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1QVP
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![BU of 1qvp by Molmil](/molmil-images/mine/1qvp) | C terminal SH3-like domain from Diphtheria toxin Repressor residues 144-226. | Descriptor: | Diphtheria toxin repressor | Authors: | Wylie, G.P, Rangachari, V, Bienkiewicz, E.A, Marin, V, Bhattacharya, N, Love, J.F, Murphy, J.R, Logan, T.M. | Deposit date: | 2003-08-28 | Release date: | 2004-11-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch. Biochemistry, 44, 2005
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1QRG
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![BU of 1qrg by Molmil](/molmil-images/mine/1qrg) | A CLOSER LOOK AND THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA | Descriptor: | CARBONIC ANHYDRASE, ZINC ION | Authors: | Iverson, T.M, Alber, B.E, Kisker, C, Ferry, J.G, Rees, D.C. | Deposit date: | 1999-06-13 | Release date: | 1999-06-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry, 39, 2000
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1QW1
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![BU of 1qw1 by Molmil](/molmil-images/mine/1qw1) | Solution Structure of the C-Terminal Domain of DtxR residues 110-226 | Descriptor: | Diphtheria toxin repressor | Authors: | Wylie, G.P, Rangachari, V, Bienkiewicz, E.A, Love, J.F, Murphy, J.R, Logan, T.M. | Deposit date: | 2003-08-29 | Release date: | 2005-03-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch. Biochemistry, 44, 2005
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1R0Q
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![BU of 1r0q by Molmil](/molmil-images/mine/1r0q) | Characterization of the conversion of the malformed, recombinant cytochrome rc552 to a 2-formyl-4-vinyl (Spirographis) heme | Descriptor: | 2-FORMYL-PROTOPORPHRYN IX, Cytochrome c-552 | Authors: | Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. | Deposit date: | 2003-09-22 | Release date: | 2004-09-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry, 43, 2004
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7LGM
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![BU of 7lgm by Molmil](/molmil-images/mine/7lgm) | Cyanophycin synthetase from A. baylyi DSM587 with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cyanophycin synthase | Authors: | Sharon, I, Haque, A.S, Lahiri, I, Leschziner, A, Schmeing, T.M. | Deposit date: | 2021-01-20 | Release date: | 2021-08-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structures and function of the amino acid polymerase cyanophycin synthetase. Nat.Chem.Biol., 17, 2021
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7LG5
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![BU of 7lg5 by Molmil](/molmil-images/mine/7lg5) | |
7LGN
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![BU of 7lgn by Molmil](/molmil-images/mine/7lgn) | |