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PDB: 8 results
6QZK
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BU of 6qzk by Molmil
Structure of Clostridium butyricum Argonaute bound to a guide DNA (5' deoxycytidine) and a 19-mer target DNA
Descriptor: Clostridium butyricum Argonaute, DNA target (5'-D(T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*T)-3'), FORMIC ACID, ...
Authors:Swarts, D.C, Jinek, M, Hegge, J.W, Van der Oost, J.
Deposit date:2019-03-11
Release date:2019-04-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.548 Å)
Cite:DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.
Nucleic Acids Res., 47, 2019
5NFV
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BU of 5nfv by Molmil
Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CRISPR-associated endonuclease Cpf1, DNA non-target strand, ...
Authors:Swarts, D.C, van der Oost, J, Jinek, M.
Deposit date:2017-03-16
Release date:2017-06-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
5NG6
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BU of 5ng6 by Molmil
Crystal structure of FnCas12a bound to a crRNA
Descriptor: CRISPR-associated endonuclease Cpf1, MAGNESIUM ION, crRNA
Authors:Swarts, D.C, van der Oost, J, Jinek, M.
Deposit date:2017-03-16
Release date:2017-06-14
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.342 Å)
Cite:Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
6I1L
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BU of 6i1l by Molmil
Crystal structure of FnCas12a in complex with a crRNA guide and ssDNA target
Descriptor: CITRIC ACID, CRISPR-associated endonuclease Cas12a, MAGNESIUM ION, ...
Authors:Jinek, M, Swarts, D.C.
Deposit date:2018-10-29
Release date:2019-01-23
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Mol. Cell, 73, 2019
6I1K
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BU of 6i1k by Molmil
Crystal structure of catalytically inactive FnCas12a in complex with a crRNA guide and a dsDNA target
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas12a, DNA non-target strand (33-MER), ...
Authors:Jinek, M, Swarts, D.C.
Deposit date:2018-10-29
Release date:2019-01-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Mol. Cell, 73, 2019
9IAB
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BU of 9iab by Molmil
Structure of the Argonaute-associated Cas4 family protein 1 (ACE1) from Chroococcidiopsis thermalis (CtACE1)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, IRON/SULFUR CLUSTER, PD-(D/E)XK endonuclease-like domain-containing protein, ...
Authors:Bobadilla Ugarte, P, Halter, S, Jinek, M, Swarts, D.C.
Deposit date:2025-02-09
Release date:2025-04-23
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA.
Mol.Cell, 85, 2025
9IAD
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BU of 9iad by Molmil
Chroococcidiopsis thermalis Argonaute (CtAgo) bound to the 3' end of a guide DNA
Descriptor: DNA (5'-D(P*TP*TP*GP*T)-3'), Protein argonaute
Authors:Bobadilla Ugarte, P, Swarts, D.C.
Deposit date:2025-02-09
Release date:2025-04-23
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA.
Mol.Cell, 85, 2025
9IAC
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BU of 9iac by Molmil
Structure of the Argonaute-associated Cas4 family protein 1 (ACE1) from Microcystis aeruginosa (MaACE1)
Descriptor: 1,2-ETHANEDIOL, IRON/SULFUR CLUSTER, MAGNESIUM ION, ...
Authors:Bobadilla Ugarte, P, Halter, S, Jinek, M, Swarts, D.C.
Deposit date:2025-02-09
Release date:2025-04-23
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA.
Mol.Cell, 85, 2025

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PDB entries from 2025-06-04

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