6QZK
Structure of Clostridium butyricum Argonaute bound to a guide DNA (5' deoxycytidine) and a 19-mer target DNA
Summary for 6QZK
Entry DOI | 10.2210/pdb6qzk/pdb |
Descriptor | Clostridium butyricum Argonaute, siDNA guide (5'-D(P*CP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), DNA target (5'-D(T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*T)-3'), ... (6 entities in total) |
Functional Keywords | argonaute, pago, ago, cbago, hydrolase |
Biological source | Clostridium butyricum More |
Total number of polymer chains | 3 |
Total formula weight | 98338.40 |
Authors | Swarts, D.C.,Jinek, M.,Hegge, J.W.,Van der Oost, J. (deposition date: 2019-03-11, release date: 2019-04-24, Last modification date: 2024-01-24) |
Primary citation | Hegge, J.W.,Swarts, D.C.,Chandradoss, S.D.,Cui, T.J.,Kneppers, J.,Jinek, M.,Joo, C.,van der Oost, J. DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute. Nucleic Acids Res., 47:5809-5821, 2019 Cited by PubMed: 31069393DOI: 10.1093/nar/gkz306 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.548 Å) |
Structure validation
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