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PDB: 8 件
7Q4A
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BU of 7q4a by Molmil
Toxoplasma gondii PRP4K kinase domain (L715F) bound to altiratinib
分子名称: Altiratinib, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Swale, C, Bellini, V, Bowler, M.
登録日2021-10-29
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase.
Sci Transl Med, 14, 2022
6XU2
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BU of 6xu2 by Molmil
Human karyopherin RanBP5 (isoform-3)
分子名称: Antipain, Importin-5, NICKEL (II) ION
著者Swale, C, McCarthy, A.A, Berger, I, Bieniossek, C, Delmas, B, Ruigrok, R.W.H, Crepin, T.
登録日2020-01-17
公開日2020-04-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.834 Å)
主引用文献X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking.
J.Mol.Biol., 432, 2020
6XTE
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BU of 6xte by Molmil
Human karyopherin RanBP5 (isoform-1)
分子名称: Antipain, CHLORIDE ION, Importin-5, ...
著者Swale, C, McCarthy, A.A, Ruigrok, R.W.H, Crepin, T.
登録日2020-01-16
公開日2020-04-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking.
J.Mol.Biol., 432, 2020
7NJC
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BU of 7njc by Molmil
Crystal structure of the Toxoplasma CPSF4 YTH-domain in complex with a 7 mer m6A-modified RNA
分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, N-methyladenosine, RNA (5'-R(*(6MZ)P*CP*A)-3'), ...
著者Swale, C, Bowler, M.W.
登録日2021-02-16
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma .
Elife, 10, 2021
7NH2
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BU of 7nh2 by Molmil
Crystal structure of Toxoplasma CPSF4-YTH domain bound to m6A
分子名称: TETRAETHYLENE GLYCOL, Zinc finger (CCCH type) motif-containing protein, ~{N},9-dimethylpurin-6-amine
著者Swale, C, Bowler, M.W.
登録日2021-02-09
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma .
Elife, 10, 2021
7NG2
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BU of 7ng2 by Molmil
Crystal structure of Toxoplasma CPSF4-YTH domain in apo form
分子名称: ISOPROPYL ALCOHOL, Zinc finger (CCCH type) motif-containing protein
著者Swale, C, Bowler, M.W.
登録日2021-02-08
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma .
Elife, 10, 2021
6Q5A
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BU of 6q5a by Molmil
Crystal structure of Cryptosporidium hominis CPSF3 in the apo form
分子名称: Cleavage and Polyadenylation Specificity Factor 3, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Palencia, A, Swale, C.
登録日2018-12-07
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection.
Sci Transl Med, 11, 2019
6Q55
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BU of 6q55 by Molmil
Crystal structure of Cryptosporidium hominis CPSF3 in complex with Compound 61
分子名称: 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-5-yl]propanoic acid, Cleavage and Polyadenylation Specificity Factor 3 (CPSF3), GLYCEROL, ...
著者Palencia, A, Swale, C.
登録日2018-12-07
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection.
Sci Transl Med, 11, 2019

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件を2024-11-06に公開中

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