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PDB: 270 results

2LJ4
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BU of 2lj4 by Molmil
Solution structure of the TbPIN1
Descriptor: Peptidyl-prolyl cis-trans isomerase/rotamase, putative
Authors:Sun, L, Lin, D, Zhao, Y.
Deposit date:2011-09-06
Release date:2012-08-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural analysis of the single-domain parvulin TbPin1.
Plos One, 7, 2012
4UIS
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BU of 4uis by Molmil
The cryoEM structure of human gamma-Secretase complex
Descriptor: GAMMA-SECRETASE, LYSOZYME
Authors:Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y.
Deposit date:2015-04-03
Release date:2015-06-10
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
4OFB
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BU of 4ofb by Molmil
Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
Descriptor: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
Authors:Sun, L, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-14
Release date:2015-04-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015
3V0U
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BU of 3v0u by Molmil
Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding
Descriptor: Perakine reductase
Authors:Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J.
Deposit date:2011-12-08
Release date:2012-02-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
6DIZ
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BU of 6diz by Molmil
EV-A71 strain 11316 complexed with tryptophan dendrimer MADAL_0385
Descriptor: SPHINGOSINE, VP1, VP2, ...
Authors:Sun, L, Lee, H, Thibaut, H.J, Rivero-Buceta, E, Martinez-Gualda, B, Delang, L, Leyssen, P, Gago, F, San-Felix, A, Hafenstein, S, Mirabelli, C, Neyts, J.
Deposit date:2018-05-24
Release date:2019-04-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Viral engagement with host (co-)receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid.
Plos Pathog., 15, 2019
8K0Z
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BU of 8k0z by Molmil
ABCG25 Wild Type purified with DDM in the apo-state
Descriptor: ABC transporter G family member 25
Authors:Sun, L, Liu, X, Ying, W, Liao, L, Wei, H.
Deposit date:2023-07-10
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:ABCG25 Wild Type purified with DDM in the apo-state
To Be Published
8K0X
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BU of 8k0x by Molmil
ABCG25 Wild Type purified with DDM in the ABA-bound state
Descriptor: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABC transporter G family member 25
Authors:Sun, L, Liu, X, Ying, W, Liao, L, Wei, H.
Deposit date:2023-07-10
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:ABCG25 Wild Type purified with DDM in the ABA-bound state
To Be Published
5HLJ
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BU of 5hlj by Molmil
Crystal Structure of Major Envelope Protein VP24 from White Spot Syndrome Virus
Descriptor: VP24
Authors:Sun, L.F, Su, Y.T, Zhao, Y.H, Fu, Z.Q, Wu, Y.K.
Deposit date:2016-01-15
Release date:2016-09-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Crystal Structure of Major Envelope Protein VP24 from White Spot Syndrome Virus
Sci Rep, 6, 2016
8KDT
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BU of 8kdt by Molmil
The local refined map of SARS-CoV Spike protein complexed with antibody PW5-5
Descriptor: PW5-5 heavy chain, PW5-5 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-10
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
8KEP
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BU of 8kep by Molmil
The local refined map of SARS-CoV-2 Omicron BA.1 Spike complexed with antibody PW5-570
Descriptor: PW5-570 heavy chain, PW5-570 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-13
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
8KEK
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BU of 8kek by Molmil
Monomer state of SARS-CoV Spike protein complexed with antibody PW5-535
Descriptor: PW5-535 heavy chain, PW5-535 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-11
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
8KDR
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BU of 8kdr by Molmil
The local refined map of SARS-CoV-2 XBB Variant Spike protein complexed with antibody PW5-535
Descriptor: PW5-535 heavy chain, PW5-535 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-10
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
8KEJ
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BU of 8kej by Molmil
Monomer state of SARS-CoV-2 XBB Variant Spike protein trimer complexed with antibody PW5-5
Descriptor: PW5-5 heavy chain, PW5-5 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-11
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
7YKS
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BU of 7yks by Molmil
Structure of TRPA1 in Drosophila melanogaster in a state with 5 ankyrin repeats determined
Descriptor: Transient receptor potential cation channel subfamily A member 1
Authors:Sun, L, Liu, X, Yang, Z, Wang, X.
Deposit date:2022-07-23
Release date:2023-07-26
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular architecture and gating mechanisms of the Drosophila TRPA1 channel.
Cell Discov, 9, 2023
7YKR
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BU of 7ykr by Molmil
Structure of TRPA1 in Drosophila melanogaster in a state with 17 ankyrin repeats determined
Descriptor: Transient receptor potential cation channel subfamily A member 1
Authors:Sun, L, Liu, X, Yang, Z, Wang, X.
Deposit date:2022-07-23
Release date:2023-07-26
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular architecture and gating mechanisms of the Drosophila TRPA1 channel.
Cell Discov, 9, 2023
8JWE
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BU of 8jwe by Molmil
The open structure of the mechanosensitive channel MSL10 in Arabidopsis thaliana
Descriptor: Mechanosensitive ion channel protein 10
Authors:Sun, L, Liu, X, Li, X.
Deposit date:2023-06-28
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Structural insights into a Plant Mechanosensitive Ion Channel AtMSL10
To be published
8KER
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BU of 8ker by Molmil
Structure of SARS-CoV-2 XBB Variant Spike protein complexed with broadly neutralizing antibody PW5-535
Descriptor: PW5-535 heavy chain, PW5-535 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-13
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
8KDS
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BU of 8kds by Molmil
Trimer state of SARS-CoV Spike protein complexed with antibody PW5-535
Descriptor: PW5-535 heavy chain, PW5-535 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-10
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
8KDM
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BU of 8kdm by Molmil
Structure of SARS-CoV Spike protein complexed with antibody PW5-5
Descriptor: PW5-5 heavy chain, PW5-5 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-09
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
8KEO
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BU of 8keo by Molmil
Structure of SARS-CoV-2 Omicron BA.1 Spike complexed with antibody PW5-570
Descriptor: PW5-570 heavy chain, PW5-570 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-13
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
8KEQ
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BU of 8keq by Molmil
State 1 of SARS-CoV-2 XBB Variant Spike protein trimer complexed with antibody PW5-5
Descriptor: PW5-5 heavy chain, PW5-5 light chain, Spike glycoprotein
Authors:Sun, L, Mao, Q, Wang, Y.
Deposit date:2023-08-13
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Cell Discov, 10, 2024
5KNN
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BU of 5knn by Molmil
Evolutionary gain of alanine mischarging to non-cognate tRNAs with a G4:U69 base pair
Descriptor: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, Alanine--tRNA ligase, cytoplasmic
Authors:Sun, L, He, W, Yang, X.-L.
Deposit date:2016-06-28
Release date:2016-09-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.
J.Am.Chem.Soc., 138, 2016
4XH3
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BU of 4xh3 by Molmil
Mechanistic insights into anchorage of the contractile ring from yeast to humans
Descriptor: Actin-binding protein anillin
Authors:Sun, L.F, Guan, R.F, Chen, Z.C.
Deposit date:2015-01-04
Release date:2015-07-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanistic insights into the anchorage of the contractile ring by anillin and mid1
Dev.Cell, 33, 2015
7RWE
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BU of 7rwe by Molmil
Crystal structure of CDK2 liganded with compound GPHR787
Descriptor: 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid, Cyclin-dependent kinase 2
Authors:Sun, L, Schonbrunn, E.
Deposit date:2021-08-19
Release date:2022-08-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice.
J.Med.Chem., 66, 2023
7RXO
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BU of 7rxo by Molmil
Crystal structure of CDK2 liganded with compound WN333
Descriptor: 1,2-ETHANEDIOL, 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-(methoxycarbonyl)benzoic acid, Cyclin-dependent kinase 2
Authors:Sun, L, Schonbrunn, E.
Deposit date:2021-08-23
Release date:2022-08-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice.
J.Med.Chem., 66, 2023

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