5KNN
Evolutionary gain of alanine mischarging to non-cognate tRNAs with a G4:U69 base pair
Summary for 5KNN
Entry DOI | 10.2210/pdb5knn/pdb |
Descriptor | Alanine--tRNA ligase, cytoplasmic, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE (2 entities in total) |
Functional Keywords | trna synthetase, ligase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P49588 |
Total number of polymer chains | 8 |
Total formula weight | 408325.18 |
Authors | Sun, L.,He, W.,Yang, X.-L. (deposition date: 2016-06-28, release date: 2016-09-28, Last modification date: 2023-09-27) |
Primary citation | Sun, L.,Gomes, A.C.,He, W.,Zhou, H.,Wang, X.,Pan, D.W.,Schimmel, P.,Pan, T.,Yang, X.L. Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair. J.Am.Chem.Soc., 138:12948-12955, 2016 Cited by PubMed: 27622773DOI: 10.1021/jacs.6b07121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
Download full validation report