7JLR
 
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7JLI
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7JLM
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7JLJ
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6C3K
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6CON
 | | Crystal structure of Mycobacterium tuberculosis IpdAB | | 分子名称: | CoA-transferase subunit alpha, CoA-transferase subunit beta | | 著者 | Crowe, A.M, Workman, S.D, Watanabe, N, Worrall, L.J, Strynadka, N.C.J, Eltis, L.D. | | 登録日 | 2018-03-12 | | 公開日 | 2018-03-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | IpdAB, a virulence factor inMycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6CO6
 | | Crystal structure of Rhodococcus jostii RHA1 IpdAB | | 分子名称: | GLYCEROL, Probable CoA-transferase alpha subunit, Probable CoA-transferase beta subunit, ... | | 著者 | Crowe, A.M, Workman, S.D, Watanabe, N, Worrall, L.J, Strynadka, N.C.J, Eltis, L.D. | | 登録日 | 2018-03-12 | | 公開日 | 2018-03-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | IpdAB, a virulence factor inMycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3VZJ
 | | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant | | 分子名称: | Endo-1,4-beta-xylanase, SULFATE ION | | 著者 | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | | 登録日 | 2012-10-14 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.406 Å) | | 主引用文献 | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
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3VZM
 | | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose | | 分子名称: | Endo-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol | | 著者 | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | | 登録日 | 2012-10-15 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
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3VZK
 | | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35E mutant | | 分子名称: | Endo-1,4-beta-xylanase, SULFATE ION | | 著者 | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | | 登録日 | 2012-10-14 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
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3VZO
 | | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose | | 分子名称: | Endo-1,4-beta-xylanase, SULFATE ION, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol | | 著者 | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | | 登録日 | 2012-10-15 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
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7K7K
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6DFE
 | | The structure of a ternary complex of E. coli WaaC | | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, ADP-heptose--LPS heptosyltransferase, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R)-1-{(2S,3S,4R,5S,6R)-6-[(1S)-1,2-dihydroxyethyl]-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl}propan-2-yl hydrogen (R)-phosphate (non-preferred name) | | 著者 | Worrall, L.J, Blaukopf, M, Withers, S.G, Strynadka, N.C.J. | | 登録日 | 2018-05-14 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex.
Structure, 26, 2018
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6DV6
 | | Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG (residues 176-end) in the open gate state | | 分子名称: | Protein InvG | | 著者 | Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J. | | 登録日 | 2018-06-22 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
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1YJ7
 | | Crystal structure of enteropathogenic E.coli (EPEC) type III secretion system protein EscJ | | 分子名称: | GLYCEROL, PHOSPHATE ION, escJ | | 著者 | Yip, C.K, Kimbrough, T.G, Felise, H.B, Vuckovic, M, Thomas, N.A, Pfuetzner, R.A, Frey, E.A, Finlay, B.B, Miller, S.I, Strynadka, N.C.J. | | 登録日 | 2005-01-13 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural characterization of the molecular platform for type III secretion system assembly.
Nature, 435, 2005
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6DUZ
 | | Structure of the periplasmic domains of PrgH and PrgK from the assembled Salmonella type III secretion injectisome needle complex | | 分子名称: | Lipoprotein PrgK, Protein PrgH | | 著者 | Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J. | | 登録日 | 2018-06-22 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
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6DZ8
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2WNB
 | | Crystal Structure of a Mammalian Sialyltransferase in complex with disaccharide and CMP | | 分子名称: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1, CYTIDINE-5'-MONOPHOSPHATE, HYDROXY(2-HYDROXYPHENYL)OXOAMMONIUM, ... | | 著者 | Rao, F.V, Rich, J.R, Raikic, B, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | | 登録日 | 2009-07-08 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural Insight Into Mammalian Sialyltransferases.
Nat.Struct.Mol.Biol., 16, 2009
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2OYM
 | | Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex | | 分子名称: | Endoglycoceramidase II, N-{[(2R,3R,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PYRROLIDIN-2-YL]METHYL}-4-(DIMETHYLAMINO)BENZAMIDE, SODIUM ION | | 著者 | Caines, M.E.C, Strynadka, N.C.J. | | 登録日 | 2007-02-22 | | 公開日 | 2007-03-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.
Angew.Chem.Int.Ed.Engl., 46, 2007
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2WNF
 | | Crystal Structure of a Mammalian Sialyltransferase in complex with Gal-beta-1-3GalNAc-ortho-nitrophenol | | 分子名称: | CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, HYDROXY(2-HYDROXYPHENYL)OXOAMMONIUM, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | | 著者 | Rao, F.V, Rich, J.R, Raikic, B, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | | 登録日 | 2009-07-09 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structural Insight Into Mammalian Sialyltransferases.
Nat.Struct.Mol.Biol., 16, 2009
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6XHT
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7KGN
 | | S. Typhi YcbB - ertapenem complex | | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, L,D-transpeptidase | | 著者 | Caveney, N.A, Strynadka, N.C.J. | | 登録日 | 2020-10-18 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections.
Antimicrob.Agents Chemother., 65, 2021
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7KGM
 | | C. rodentium YcbB - ertapenem complex | | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Putative exported protein | | 著者 | Caveney, N.A, Strynadka, N.C.J. | | 登録日 | 2020-10-17 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections.
Antimicrob.Agents Chemother., 65, 2021
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7KCX
 | | Crystal structure of S. aureus penicillin-binding protein 4 (PBP4) mutant (R200L) in complex with cefoxitin | | 分子名称: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 4, ... | | 著者 | Alexander, J.A.N, Strynadka, N.C.J. | | 登録日 | 2020-10-07 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | PBP4-mediated beta-lactam resistance among clinical strains of Staphylococcus aureus.
J.Antimicrob.Chemother., 76, 2021
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7KCV
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