6YKQ
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![BU of 6ykq by Molmil](/molmil-images/mine/6ykq) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11c | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKN
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![BU of 6ykn by Molmil](/molmil-images/mine/6ykn) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11b | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKW
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![BU of 6ykw by Molmil](/molmil-images/mine/6ykw) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11h | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKX
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![BU of 6ykx by Molmil](/molmil-images/mine/6ykx) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11j | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKK
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![BU of 6ykk by Molmil](/molmil-images/mine/6ykk) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 15 | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.236 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKV
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![BU of 6ykv by Molmil](/molmil-images/mine/6ykv) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11g | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKO
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![BU of 6yko by Molmil](/molmil-images/mine/6yko) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11a | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKS
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![BU of 6yks by Molmil](/molmil-images/mine/6yks) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11d | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKL
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![BU of 6ykl by Molmil](/molmil-images/mine/6ykl) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11k | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKT
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![BU of 6ykt by Molmil](/molmil-images/mine/6ykt) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11e | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6YKU
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![BU of 6yku by Molmil](/molmil-images/mine/6yku) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11f | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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7AP2
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![BU of 7ap2 by Molmil](/molmil-images/mine/7ap2) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound LeuS7HMDDA | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-10-15 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors. Molecules, 25, 2020
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7A0P
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![BU of 7a0p by Molmil](/molmil-images/mine/7a0p) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11i | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-08-10 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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3UGH
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![BU of 3ugh by Molmil](/molmil-images/mine/3ugh) | Crystal structure of a 6-SST/6-SFT from Pachysandra terminalis in complex with 6-kestose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... | 著者 | Lammens, W, Rabijns, A, Van Laere, A, Strelkov, S.V, Van den Ende, W. | 登録日 | 2011-11-02 | 公開日 | 2011-11-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of 6-SST/6-SFT from Pachysandra terminalis, a plant fructan biosynthesizing enzyme in complex with its acceptor substrate 6-kestose. Plant J., 70, 2012
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1USE
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![BU of 1use by Molmil](/molmil-images/mine/1use) | human VASP tetramerisation domain | 分子名称: | VASODILATOR-STIMULATED PHOSPHOPROTEIN | 著者 | Kuhnel, K, Jarchau, T, Wolf, E, Schlichting, I, Walter, U, Wittinghofer, A, Strelkov, S.V. | 登録日 | 2003-11-21 | 公開日 | 2004-11-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The Vasp Tetramerization Domain is a Right-Handed Coiled Coil Based on a 15-Residue Repeat Proc.Natl.Acad.Sci.USA, 101, 2004
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7AP3
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![BU of 7ap3 by Molmil](/molmil-images/mine/7ap3) | Crystal structure of E. coli tyrosyl-tRNA synthetase in complex with TyrS7HMDDA | 分子名称: | SODIUM ION, Tyrosine--tRNA ligase, [(2~{R},3~{S},4~{R},5~{R})-5-[7-azanyl-5-(hydroxymethyl)benzimidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(2~{S})-2-azanyl-3-(4-hydroxyphenyl)propanoyl]sulfamate | 著者 | De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-10-15 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors. Molecules, 25, 2020
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7AP1
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![BU of 7ap1 by Molmil](/molmil-images/mine/7ap1) | Klebsiella pneumoniae Seryl-tRNA synthetase in Complex with Compound SerS7HMDDA | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Serine-tRNA ligase, ... | 著者 | Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-10-15 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors. Molecules, 25, 2020
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3UGG
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![BU of 3ugg by Molmil](/molmil-images/mine/3ugg) | Crystal structure of a 6-SST/6-SFT from Pachysandra terminalis in complex with 1-kestose | 分子名称: | GLYCEROL, SULFATE ION, Sucrose:(Sucrose/fructan) 6-fructosyltransferase, ... | 著者 | Lammens, W, Rabijns, A, Van Laere, A, Strelkov, S.V, Van den Ende, W. | 登録日 | 2011-11-02 | 公開日 | 2011-11-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of 6-SST/6-SFT from Pachysandra terminalis, a plant fructan biosynthesizing enzyme in complex with its acceptor substrate 6-kestose. Plant J., 70, 2012
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3SWK
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![BU of 3swk by Molmil](/molmil-images/mine/3swk) | |
3SSU
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![BU of 3ssu by Molmil](/molmil-images/mine/3ssu) | |
7B69
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![BU of 7b69 by Molmil](/molmil-images/mine/7b69) | |
7B6A
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![BU of 7b6a by Molmil](/molmil-images/mine/7b6a) | BK Polyomavirus VP1 pentamer core (residues 30-299) | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, IODIDE ION, ... | 著者 | Osipov, E.M, Munawar, A, Beelen, S, Strelkov, S.V. | 登録日 | 2020-12-07 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors. Rsc Chem Biol, 3, 2022
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7B6C
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![BU of 7b6c by Molmil](/molmil-images/mine/7b6c) | BK Polyomavirus VP1 pentamer fusion with long C-terminal extended arm | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, Major capsid protein VP1,Major capsid protein VP1 | 著者 | Osipov, E.M, Beelen, S, Strelkov, S.V. | 登録日 | 2020-12-07 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.484 Å) | 主引用文献 | Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors. Rsc Chem Biol, 3, 2022
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6ZRV
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![BU of 6zrv by Molmil](/molmil-images/mine/6zrv) | Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with an Inhibitory Nanobody (VHH-s-a93, Nb93) | 分子名称: | Plasminogen activator inhibitor 1, VHH-s-a93 (Nb93) | 著者 | Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2020-07-15 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity. Int J Mol Sci, 21, 2020
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3TRT
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![BU of 3trt by Molmil](/molmil-images/mine/3trt) | |