7S2K
 
 | | Crystal structure of sulfonamide resistance enzyme Sul2 in complex with 7,8-dihydropteroate, magnesium, and pyrophosphate | | Descriptor: | 4-AMINOBENZOIC ACID, 7,8-DIHYDROPTEROATE, CHLORIDE ION, ... | | Authors: | Stogios, P.J, Skarina, T, Michalska, K, Venkatesan, M, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-09-03 | | Release date: | 2023-05-03 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics.
Nat Commun, 14, 2023
|
|
5KOL
 | | Crystal structure of the competence-damaged protein (CinA) superfamily protein ECK1530/EC0983 from Escherichia coli | | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Stogios, P.J, Wawrak, Z, Evdokimova, E, Di Leo, R, Grimshaw, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-06-30 | | Release date: | 2016-07-27 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | To be published
To Be Published
|
|
5CYV
 | | Crystal structure of CouR from Rhodococcus jostii RHA1 bound to p-coumaroyl-CoA | | Descriptor: | ACETATE ION, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Stogios, P.J, Xu, X, Dong, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2015-07-30 | | Release date: | 2015-08-12 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism.
Nucleic Acids Res., 44, 2016
|
|
8SCD
 | | Crystal structure of sulfonamide resistance enzyme Sul3 in complex with reaction intermediate | | Descriptor: | 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, 4-AMINOBENZOIC ACID, CHLORIDE ION, ... | | Authors: | Stogios, P.J, Venkatesan, M, Michalska, K, Mesa, N, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2023-04-05 | | Release date: | 2023-05-03 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics.
Nat Commun, 14, 2023
|
|
5CBK
 | | Crystal structure of the strigolactone receptor ShHTL5 from Striga hermonthica | | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Stogios, P.J, Onopriyenko, O, Yim, V, Savchenko, A. | | Deposit date: | 2015-07-01 | | Release date: | 2015-10-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.462 Å) | | Cite: | Structure-function analysis identifies highly sensitive strigolactone receptors in Striga.
Science, 350, 2015
|
|
7LAP
 | | Crystal structure of aminoglycoside acetyltransferase AAC(3)-Xa | | Descriptor: | Aminoglycoside N(3)-acetyltransferase, CHLORIDE ION, D(-)-TARTARIC ACID, ... | | Authors: | Stogios, P.J, Skarina, T, Kim, Y, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-01-06 | | Release date: | 2021-02-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
Commun Biol, 5, 2022
|
|
4LAT
 | | Crystal structure of phosphate ABC transporter, periplasmic phosphate-binding protein PstS 1 (PBP1) from Streptococcus pneumoniae Canada MDR_19A in complex with phosphate | | Descriptor: | ISOPROPYL ALCOHOL, PHOSPHATE ION, Phosphate-binding protein PstS 1 | | Authors: | Stogios, P.J, Wawrzak, Z, Kudritska, M, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2013-06-20 | | Release date: | 2013-07-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Crystal structure of phosphate ABC transporter, periplasmic phosphate-binding protein PstS 1 (PBP1) from Streptococcus pneumoniae Canada MDR_19A in complex with phosphate
To be Published
|
|
7LAO
 | | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IIb | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aminoglycoside N(3)-acetyltransferase III, MAGNESIUM ION | | Authors: | Stogios, P.J, Evdokimova, E, Osipiuk, J, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-01-06 | | Release date: | 2021-01-20 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
Commun Biol, 5, 2022
|
|
7LGO
 | | Crystal structure of the nucleic acid binding domain (NAB) of Nsp3 from SARS-CoV-2 | | Descriptor: | Non-structural protein 3 | | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-01-20 | | Release date: | 2021-01-27 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of the nucleic acid binding domain (NAB) of Nsp3 from SARS-CoV-2
To Be Published
|
|
4JCC
 | | Crystal structure of iron uptake ABC transporter substrate-binding protein PiuA from Streptococcus pneumoniae Canada MDR_19A | | Descriptor: | CHLORIDE ION, ISOPROPYL ALCOHOL, Iron-compound ABC transporter, ... | | Authors: | Stogios, P.J, Wawrzak, Z, Kudritska, M, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2013-02-21 | | Release date: | 2013-03-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.133 Å) | | Cite: | Crystal structure of iron uptake ABC transporter substrate-binding protein PiuA from Streptococcus pneumoniae Canada MDR_19A
TO BE PUBLISHED
|
|
7MX5
 | | Crystal structure of TolB from Acinetobacter baumannii | | Descriptor: | Tol-Pal system protein TolB | | Authors: | Stogios, P.J, Evdokimova, E, Endres, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-05-18 | | Release date: | 2021-05-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Crystal structure of TolB from Acinetobacter baumannii
To Be Published
|
|
6OZ1
 | | Crystal structure of the adenylation (A) domain of the carboxylate reductase (CAR) GR01_22995 from Mycobacterium chelonae | | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Fedorchuk, T, Khusnutdinova, A, Yakunin, A.F, Savchenko, A. | | Deposit date: | 2019-05-15 | | Release date: | 2020-04-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | One-Pot Biocatalytic Transformation of Adipic Acid to 6-Aminocaproic Acid and 1,6-Hexamethylenediamine Using Carboxylic Acid Reductases and Transaminases.
J.Am.Chem.Soc., 142, 2020
|
|
4W8K
 | | Crystal structure of a putative Cas1 enzyme from Vibrio phage ICP1 | | Descriptor: | Cas1 protein, POTASSIUM ION | | Authors: | Stogios, P.J, Wawrzak, Z, Onopriyeno, O, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2014-08-25 | | Release date: | 2014-09-17 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | To be published
To Be Published
|
|
6WON
 | | Crystal structure of acetoin dehydrogenase YohF from Salmonella typhimurium | | Descriptor: | CHLORIDE ION, SULFATE ION, YohF | | Authors: | Stogios, P.J, Skarina, T, Mesa, N, Endres, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-04-25 | | Release date: | 2020-05-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Crystal structure of acetoin dehydrogenase YohF from Salmonella typhimurium
To Be Published
|
|
5VU3
 | | Crystal structure of the competence-damaged protein (CinA) superfamily protein ECL_02051 from Enterobacter cloacae | | Descriptor: | ACETATE ION, Competence damage-inducible protein A, TETRAETHYLENE GLYCOL | | Authors: | Stogios, P.J, Skarina, T, McChesney, C, Sandoval, J, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-05-18 | | Release date: | 2017-06-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.868 Å) | | Cite: | Crystal structure of the competence-damaged protein (CinA) superfamily protein ECL_02051 from Enterobacter cloacae
To Be Published
|
|
7MWA
 | | Crystal structure of 2-octaprenyl-6-methoxyphenol hydroxylase UbiH from Acinetobacter baumannii, apoenzyme | | Descriptor: | 1,2-ETHANEDIOL, 2-polyprenyl-6-methoxyphenol 4-hydroxylase, CHLORIDE ION, ... | | Authors: | Stogios, P.J, Evdokimova, E, Endres, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-05-16 | | Release date: | 2021-05-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | UbiH from Acinetobacter baumannii
To Be Published
|
|
5VKW
 | | Crystal structure of adenylosuccinate lyase ADE13 from Candida albicans | | Descriptor: | Adenylosuccinate lyase, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-04-24 | | Release date: | 2017-05-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | Crystal structure of adenylosuccinate lyase ADE13 from Candida albicans
To Be Published
|
|
7TOH
 | | Crystal structure of carbohydrate esterase PbeAcXE, in complex with MeGlcpA-Xylp | | Descriptor: | 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose, SGNH hydrolase | | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Jurak, E, Master, E. | | Deposit date: | 2022-01-24 | | Release date: | 2022-04-13 | | Last modified: | 2022-11-02 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans.
Molecules, 27, 2022
|
|
6WQB
 | | Crystal structure of VipF from Legionella hackeliae in complex with acetyl-CoA | | Descriptor: | ACETYL COENZYME *A, N-terminal acetyltransferase, GNAT family | | Authors: | Stogios, P.J, Skarina, T, Wawrzak, Z, Sandoval, J, Di Leo, R, Savchenko, A. | | Deposit date: | 2020-04-28 | | Release date: | 2021-11-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of VipF from Legionella hackeliae in complex with acetyl-CoA
To Be Published
|
|
6WQC
 | | Crystal structure of VipF from Legionella hackeliae in complex with CoA | | Descriptor: | COENZYME A, N-terminal acetyltransferase, GNAT family | | Authors: | Stogios, P.J, Skarina, T, Wawrzak, Z, Sandoval, J, Di Leo, R, Savchenko, A. | | Deposit date: | 2020-04-28 | | Release date: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Crystal structure of VipF from Legionella hackeliae in complex with CoA
To Be Published
|
|
7TOG
 | | Crystal structure of carbohydrate esterase PbeAcXE, apoenzyme | | Descriptor: | SGNH hydrolase | | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Jurak, E, Master, E. | | Deposit date: | 2022-01-24 | | Release date: | 2022-04-13 | | Last modified: | 2022-11-02 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans.
Molecules, 27, 2022
|
|
7TOI
 | | Crystal structure of carbohydrate esterase PbeAcXE, in complex with acetate | | Descriptor: | ACETATE ION, SGNH hydrolase | | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Jurak, E, Master, E. | | Deposit date: | 2022-01-24 | | Release date: | 2022-04-13 | | Last modified: | 2022-11-02 | | Method: | X-RAY DIFFRACTION (1.13 Å) | | Cite: | Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans.
Molecules, 27, 2022
|
|
3V77
 | | Crystal structure of a putative fumarylacetoacetate isomerase/hydrolase from Oleispira antarctica | | Descriptor: | ACETATE ION, D(-)-TARTARIC ACID, Putative fumarylacetoacetate isomerase/hydrolase, ... | | Authors: | Stogios, P.J, Kagan, O, Di Leo, R, Bochkarev, A, Edwards, A.M, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2011-12-20 | | Release date: | 2012-01-18 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica.
Nat Commun, 4, 2013
|
|
6WJ8
 | | Crystal structure of gamma-aminobutyrate aminotransferase PuuE from Klebsiella pneumoniae in complex with PLP | | Descriptor: | 4-aminobutyrate aminotransferase PuuE | | Authors: | Stogios, P.J, Evdokimova, E, McChesney, C, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-04-13 | | Release date: | 2020-04-22 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Crystal structure of gamma-aminobutyrate aminotransferase PuuE from Klebsiella pneumoniae in complex with PLP
To Be Published
|
|
7ROA
 | | Crystal structure of EntV136 from Enterococcus faecalis | | Descriptor: | EntV | | Authors: | Stogios, P.J, Evdokimova, E, Kim, Y, Garsin, D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | | Deposit date: | 2021-07-30 | | Release date: | 2022-10-12 | | Last modified: | 2023-01-25 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections.
Nat Commun, 13, 2022
|
|
