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PDB: 37 results

8G7K
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mtHsp60 V72I apo focus
Descriptor: 60 kDa heat shock protein, mitochondrial
Authors:Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R.
Deposit date:2023-02-16
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
7L7I
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Cryo-EM structure of Hsp90:FKBP51:p23 closed-state complex
Descriptor: Heat shock protein HSP 90-alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Peptidyl-prolyl cis-trans isomerase FKBP5, ...
Authors:Lee, K, Thwin, A.C, Tse, E, Gates, S.N, Southworth, D.R.
Deposit date:2020-12-28
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state.
Mol.Cell, 81, 2021
7L7J
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Cryo-EM structure of Hsp90:p23 closed-state complex
Descriptor: Heat shock protein HSP 90-alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Prostaglandin E synthase 3
Authors:Lee, K, Thwin, A.C, Tse, E, Gates, S.N, Southworth, D.R.
Deposit date:2020-12-28
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state.
Mol.Cell, 81, 2021
5VJH
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Closed State CryoEM Reconstruction of Hsp104:ATPyS and FITC casein
Descriptor: FITC casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R.
Deposit date:2017-04-19
Release date:2017-07-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104.
Science, 357, 2017
5VYA
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S. cerevisiae Hsp104:casein complex, Extended Conformation
Descriptor: Alpha-S1-casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R.
Deposit date:2017-05-24
Release date:2017-07-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104.
Science, 357, 2017
5VY9
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S. cerevisiae Hsp104:casein complex, Middle Domain Conformation
Descriptor: Alpha-S1-casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R.
Deposit date:2017-05-24
Release date:2017-07-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104.
Science, 357, 2017
5VY8
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S. cerevisiae Hsp104-ADP complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Heat shock protein 104
Authors:Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R.
Deposit date:2017-05-24
Release date:2017-07-05
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104.
Science, 357, 2017
6OG2
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Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, post-state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Hyperactive disaggregase ClpB
Authors:Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R.
Deposit date:2019-04-01
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10, 2019
6OG3
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Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, NTD-trimer
Descriptor: Alpha S1-casein, Hyperactive disaggregase ClpB
Authors:Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R.
Deposit date:2019-04-01
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10, 2019
6OAY
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BU of 6oay by Molmil
Structure of the hyperactive ClpB mutant K476C, bound to casein, post-state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Hyperactive disaggregase ClpB, ...
Authors:Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10, 2019
6OG1
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Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, pre-state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Hyperactive disaggregase ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R.
Deposit date:2019-04-01
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10, 2019
6OAX
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BU of 6oax by Molmil
Structure of the hyperactive ClpB mutant K476C, bound to casein, pre-state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Hyperactive disaggregase ClpB, ...
Authors:Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10, 2019
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數據於2024-09-18公開中

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