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PDB: 1971 件

3JPT
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Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro chloro methylene triphosphate
分子名称: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
登録日2009-09-04
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
6BEL
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BU of 6bel by Molmil
Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-deoxy-5'-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, CHLORIDE ION, ...
著者Batra, V.K, Wilson, S.H.
登録日2017-10-25
公開日2018-10-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
4GXI
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R283K DNA polymerase beta binary complex with a templating 8OG
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Freudenthal, B.D, Beard, W.A, Wilson, S.H.
登録日2012-09-04
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion.
Nucleic Acids Res., 41, 2013
3JPS
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Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro methyl methylene triphosphate
分子名称: 2'-deoxy-5'-O-[(S)-{[(S)-[(1R)-1-fluoro-1-phosphonoethyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
著者Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
登録日2009-09-04
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
2FMP
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BU of 2fmp by Molmil
DNA Polymerase beta with a terminated gapped DNA substrate and ddCTP with sodium in the catalytic site
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
著者Batra, V.K, Beard, W.A, Shock, D.D, Krahn, J.M, Pedersen, L.C, Wilson, S.H.
登録日2006-01-09
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Magnesium-induced assembly of a complete DNA polymerase catalytic complex.
Structure, 14, 2006
3K9O
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The crystal structure of E2-25K and UBB+1 complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H.
登録日2009-10-16
公開日2010-09-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of E2-25K/UBB+1 Interaction for Neurotoxicity of Alzheimer Disease by Proteasome Inhibition
To be Published
5EQ4
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BU of 5eq4 by Molmil
Crystal structure of the SrpA adhesin R347E mutant from Streptococcus sanguinis
分子名称: ACETATE ION, CALCIUM ION, Platelet-binding glycoprotein
著者Loukachevitch, L.V, McCulloch, K.M, Vann, K.R, Wawrzak, Z, Anderson, S, Iverson, T.M.
登録日2015-11-12
公開日2016-01-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin.
J.Biol.Chem., 291, 2016
3TFS
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Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CFH)PP in the active site: Stereoselective binding of (S) isomer
分子名称: 2'-deoxy-5'-O-[(S)-{(S)-fluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Chamberlain, B.T, Batra, V.K, Beard, W.A, Kadina, A.P, Shock, D.D, Kashemirov, B.A, McKenna, C.E, Goodman, M.F, Wilson, S.H.
登録日2011-08-16
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Stereospecific Formation of a Ternary Complex of (S)-alpha, beta-Fluoromethylene-dATP with DNA Pol beta.
Chembiochem, 13, 2012
5EQ2
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Crystal Structure of the SrpA Adhesin from Streptococcus sanguinis
分子名称: ACETATE ION, CALCIUM ION, Platelet-binding glycoprotein
著者Loukachevitch, L.V, McCulloch, K.M, Vann, K.R, Wawrzak, Z, Anderson, S, Iverson, T.M.
登録日2015-11-12
公開日2016-01-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin.
J.Biol.Chem., 291, 2016
3MNV
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BU of 3mnv by Molmil
Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment
分子名称: 1,2-ETHANEDIOL, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ...
著者Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F.
登録日2010-04-22
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region.
Nat.Struct.Mol.Biol., 17, 2010
2F3J
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BU of 2f3j by Molmil
The solution structure of the REF2-I mRNA export factor (residues 1-155).
分子名称: RNA and export factor binding protein 2
著者Golovanov, A.P, Hautbergue, G.M, Wilson, S.A, Lian, L.Y.
登録日2005-11-21
公開日2006-10-31
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of REF2-I reveals interdomain interactions and regions involved in binding mRNA export factors and RNA.
Rna, 12, 2006
6BZH
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BU of 6bzh by Molmil
Structure of mouse RIG-I tandem CARDs
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58
著者Kershaw, N.J, D'Cruz, A.A, Babon, J.J, Nicholson, S.E.
登録日2017-12-24
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of a second binding site on the TRIM25 B30.2 domain.
Biochem. J., 475, 2018
1ZJN
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BU of 1zjn by Molmil
Human DNA Polymerase beta complexed with DNA containing an A-A mismatched primer terminus with dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H.
登録日2005-04-29
公開日2005-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate.
STRUCTURE, 13, 2005
3MYU
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BU of 3myu by Molmil
Mycoplasma genitalium MG289
分子名称: 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ACETATE ION, High affinity transport system protein p37
著者Sippel, K.H, Boehlein, S.K, Govindasamy, L, Namiki, K, Satai, Y, Quirit, J.G, Agbandje-McKenna, M, Goodison, S, Rosser, C.J, Sankaran, B, McKenna, R.
登録日2010-05-11
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins, 79, 2011
1SGY
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BU of 1sgy by Molmil
TYR 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
3N4S
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BU of 3n4s by Molmil
Structure of Csm1 C-terminal domain, P21212 form
分子名称: Monopolin complex subunit CSM1, PENTAETHYLENE GLYCOL
著者Corbett, K.D, Harrison, S.C.
登録日2010-05-22
公開日2010-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments.
Cell(Cambridge,Mass.), 142, 2010
6MR7
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BU of 6mr7 by Molmil
DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog
分子名称: 1,2-ETHANEDIOL, 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, ...
著者Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A.
登録日2018-10-11
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition.
Nucleic Acids Res., 47, 2019
3N7N
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Structure of Csm1/Lrs4 complex
分子名称: Monopolin complex subunit CSM1, Monopolin complex subunit LRS4
著者Corbett, K.D, Harrison, S.C.
登録日2010-05-27
公開日2010-09-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments.
Cell(Cambridge,Mass.), 142, 2010
2VIX
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BU of 2vix by Molmil
Methylated Shigella flexneri MxiC
分子名称: ACETATE ION, GLYCEROL, PROTEIN MXIC
著者Deane, J.E, Roversi, P, King, C, Johnson, S, Lea, S.M.
登録日2007-12-05
公開日2008-03-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of the Shigella Flexneri Type 3 Secretion System Protein Mxic Reveal Conformational Variability Amongst Homologues.
J.Mol.Biol., 377, 2008
3N4R
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BU of 3n4r by Molmil
Structure of Csm1 C-terminal domain, R3 form
分子名称: MALONATE ION, Monopolin complex subunit CSM1, PENTAETHYLENE GLYCOL
著者Corbett, K.D, Harrison, S.C.
登録日2010-05-22
公開日2010-09-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments.
Cell(Cambridge,Mass.), 142, 2010
1SGD
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BU of 1sgd by Molmil
ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
1S4S
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BU of 1s4s by Molmil
Reaction Intermediate in the Photocycle of PYP, intermediate occupied between 100 micro-seconds to 5 milli-seconds
分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
著者Schmidt, M, Pahl, R, Srajer, V, Anderson, S, Ren, Z, Ihee, H, Rajagopal, S, Moffat, K.
登録日2004-01-17
公開日2004-04-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Protein kinetics: Structures of intermediates and reaction mechanism from time-resolved x-ray data
Proc.Natl.Acad.Sci.USA, 101, 2004
2VJ5
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BU of 2vj5 by Molmil
Shigella flexneri MxiC
分子名称: PROTEIN MXIC
著者Deane, J.E, Roversi, P, King, C, Johnson, S, Lea, S.M.
登録日2007-12-06
公開日2008-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of the Shigella Flexneri Type 3 Secretion System Protein Mxic Reveal Conformational Variability Amongst Homologues.
J.Mol.Biol., 377, 2008
3N4X
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Structure of Csm1 full-length
分子名称: Monopolin complex subunit CSM1
著者Corbett, K.D, Harrison, S.C.
登録日2010-05-23
公開日2010-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.408 Å)
主引用文献The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments.
Cell(Cambridge,Mass.), 142, 2010
1ZJM
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Human DNA Polymerase beta complexed with DNA containing an A-A mismatched primer terminus
分子名称: 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', DNA polymerase beta, ...
著者Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H.
登録日2005-04-29
公開日2005-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate.
STRUCTURE, 13, 2005

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