3MP9
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![BU of 3mp9 by Molmil](/molmil-images/mine/3mp9) | Structure of Streptococcal protein G B1 domain at pH 3.0 | 分子名称: | FORMIC ACID, Immunoglobulin G-binding protein G | 著者 | Tomlinson, J.H, Green, V.L, Baker, P.J, Williamson, M.P. | 登録日 | 2010-04-26 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural origins of pH-dependent chemical shifts in the B1 domain of protein G. Proteins, 78, 2010
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5IZ2
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2MZW
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![BU of 2mzw by Molmil](/molmil-images/mine/2mzw) | Staphylococcus aureus FusB:EF-GC3 complex | 分子名称: | Elongation factor G, Far1, ZINC ION | 著者 | Tomlinson, J.H, Thompson, G.S, Kalverda, A.P, Zhuravleva, A, O'Neill, A. | 登録日 | 2015-02-25 | 公開日 | 2016-01-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A target-protection mechanism of antibiotic resistance at atomic resolution: insights into FusB-type fusidic acid resistance. Sci Rep, 6, 2016
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4K87
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![BU of 4k87 by Molmil](/molmil-images/mine/4k87) | Crystal structure of human prolyl-tRNA synthetase (substrate bound form) | 分子名称: | ADENOSINE, PROLINE, Proline--tRNA ligase, ... | 著者 | Hwang, K.Y, Son, J.H, Lee, E.H. | 登録日 | 2013-04-18 | 公開日 | 2013-10-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone. Acta Crystallogr.,Sect.D, 69, 2013
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4K88
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![BU of 4k88 by Molmil](/molmil-images/mine/4k88) | Crystal structure of human prolyl-tRNA synthetase (halofuginone bound form) | 分子名称: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Proline--tRNA ligase, ZINC ION | 著者 | Hwang, K.Y, Son, J.H, Lee, E.H. | 登録日 | 2013-04-18 | 公開日 | 2013-10-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.619 Å) | 主引用文献 | Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone. Acta Crystallogr.,Sect.D, 69, 2013
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4K86
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1UC7
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![BU of 1uc7 by Molmil](/molmil-images/mine/1uc7) | Crystal structure of DsbDgamma | 分子名称: | Thiol:disulfide interchange protein dsbD | 著者 | Kim, J.H, Kim, S.J, Jeong, D.G, Son, J.H, Ryu, S.E. | 登録日 | 2003-04-09 | 公開日 | 2004-04-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of DsbDgamma reveals the mechanism of redox potential shift and substrate specificity(1) FEBS LETT., 543, 2003
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1XM2
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![BU of 1xm2 by Molmil](/molmil-images/mine/1xm2) | Crystal structure of Human PRL-1 | 分子名称: | SULFATE ION, Tyrosine Phosphatase | 著者 | Jeong, D.G, Kim, S.J, Kim, J.H, Son, J.H, Ryu, S.E. | 登録日 | 2004-10-01 | 公開日 | 2005-01-25 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms J.Mol.Biol., 345, 2005
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1ZZW
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![BU of 1zzw by Molmil](/molmil-images/mine/1zzw) | Crystal Structure of catalytic domain of Human MAP Kinase Phosphatase 5 | 分子名称: | 1,2-ETHANEDIOL, Dual specificity protein phosphatase 10, SULFATE ION | 著者 | Jeong, D.G, Yoon, T.S, Kim, J.H, Shim, M.Y, Jeong, S.K, Son, J.H, Ryu, S.E, Kim, S.J. | 登録日 | 2005-06-14 | 公開日 | 2006-07-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of Human MAP Kinase Phosphatase 5: Structural Insight into Constitutively Active Phosphatase. J.Mol.Biol., 360, 2006
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1YZ4
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![BU of 1yz4 by Molmil](/molmil-images/mine/1yz4) | Crystal structure of DUSP15 | 分子名称: | SULFATE ION, dual specificity phosphatase-like 15 isoform a, octyl beta-D-glucopyranoside | 著者 | Kim, S.J, Ryu, S.E, Jeong, D.G, Yoon, T.S, Kim, J.H, Cho, Y.H, Jeong, S.K, Lee, J.W, Son, J.H. | 登録日 | 2005-02-28 | 公開日 | 2005-11-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase Proteins, 61, 2005
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6CWY
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![BU of 6cwy by Molmil](/molmil-images/mine/6cwy) | Crystal structure of SUMO E1 in complex with an allosteric inhibitor | 分子名称: | GLYCEROL, MAGNESIUM ION, SULFATE ION, ... | 著者 | Lv, Z, Yuan, L, Atkison, J.H, Williams, K.M, Olsen, S.K. | 登録日 | 2018-04-01 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.462 Å) | 主引用文献 | Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun, 9, 2018
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1JXN
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![BU of 1jxn by Molmil](/molmil-images/mine/1jxn) | Crystal Structure of the Lectin I from Ulex europaeus in complex with the methyl glycoside of alpha-L-fucose | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, MANGANESE (II) ION, ... | 著者 | Audette, G.F, Olson, D.J.H, Ross, A.R.S, Quail, J.W, Delbaere, L.T.J. | 登録日 | 2001-09-07 | 公開日 | 2002-12-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Examination of the Structural Basis for O(H) Blood Group Specificity by Ulex europaeus Lectin I Can.J.Chem., 80, 2002
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4RCP
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![BU of 4rcp by Molmil](/molmil-images/mine/4rcp) | Crystal structure of Plk1 Polo-box domain in complex with PL-2 | 分子名称: | 1,2-ETHANEDIOL, PL-2, Serine/threonine-protein kinase PLK1 | 著者 | Lee, W.C, Song, J.H, Kim, H.Y. | 登録日 | 2014-09-16 | 公開日 | 2014-11-12 | 最終更新日 | 2015-01-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1. J.Med.Chem., 58, 2015
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3U66
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![BU of 3u66 by Molmil](/molmil-images/mine/3u66) | Crystal structure of T6SS SciP/TssL from Escherichia Coli Enteroaggregative 042 | 分子名称: | GLYCEROL, Putative type VI secretion protein | 著者 | Durand, E, Aschtgen, M.S, Zoued, A, Spinelli, S, Watson, P.J.H, Cambillau, C, Cascales, E. | 登録日 | 2011-10-12 | 公開日 | 2012-03-07 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems. J.Biol.Chem., 287, 2012
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5KXA
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![BU of 5kxa by Molmil](/molmil-images/mine/5kxa) | Selective Inhibition of Autotaxin is Effective in Mouse Models of Liver Fibrosis | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[6-chloranyl-2-cyclopropyl-1-(1-ethylpyrazol-4-yl)-7-fluoranyl-indol-3-yl]sulfanyl-2-fluoranyl-benzoic acid, CALCIUM ION, ... | 著者 | Stein, A.J, Bain, G, Hutchinson, J.H, Evans, J.F. | 登録日 | 2016-07-20 | 公開日 | 2016-11-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis. J. Pharmacol. Exp. Ther., 360, 2017
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5IDH
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5ICH
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5IBY
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5ICL
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4LKM
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![BU of 4lkm by Molmil](/molmil-images/mine/4lkm) | Crystal structure of Plk1 Polo-box domain in complex with PL-74 | 分子名称: | GLYCEROL, PL-74, SULFATE ION, ... | 著者 | Lee, W.C, Song, J.H, Kim, H.Y. | 登録日 | 2013-07-08 | 公開日 | 2013-12-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Exploring the binding nature of pyrrolidine pocket-dependent interactions in the polo-box domain of polo-like kinase 1 Plos One, 8, 2013
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4LKL
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1Y6A
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![BU of 1y6a by Molmil](/molmil-images/mine/1y6a) | Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor | 分子名称: | N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE, Vascular endothelial growth factor receptor 2 | 著者 | Harris, P.A, Cheung, M, Hunter, R.N, Brown, M.L, Veal, J.M, Nolte, R.T, Wang, L, Liu, W, Crosby, R.M, Johnson, J.H, Epperly, A.H, Kumar, R, Luttrell, D.K, Stafford, J.A. | 登録日 | 2004-12-05 | 公開日 | 2005-06-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors. J.Med.Chem., 48, 2005
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1Y6B
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![BU of 1y6b by Molmil](/molmil-images/mine/1y6b) | Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor | 分子名称: | N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE, Vascular endothelial growth factor receptor 2 | 著者 | Harris, P.A, Cheung, M, Hunter, R.N, Brown, M.L, Veal, J.M, Nolte, R.T, Wang, L, Liu, W, Crosby, R.M, Johnson, J.H, Epperly, A.H, Kumar, R, Luttrell, D.K, Stafford, J.A. | 登録日 | 2004-12-05 | 公開日 | 2005-06-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors. J.Med.Chem., 48, 2005
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5UMB
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![BU of 5umb by Molmil](/molmil-images/mine/5umb) | Crystal structure of ATPase domain of Malaria GRP78 with ADP bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone DnaK, MAGNESIUM ION, ... | 著者 | Chen, Y, Antoshchenko, T, Pizarro, J.C, Song, J.H, Park, H. | 登録日 | 2017-01-26 | 公開日 | 2022-07-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Repurposing drugs to target the malaria parasite unfolding protein response. Sci Rep, 8, 2018
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6NYA
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![BU of 6nya by Molmil](/molmil-images/mine/6nya) | Crystal Structure of ubiquitin E1 (Uba1) in complex with Ubc3 (Cdc34) and ubiquitin | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Olsen, S.K, Williams, K.M, Atkison, J.H. | 登録日 | 2019-02-11 | 公開日 | 2019-08-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.065 Å) | 主引用文献 | Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34. Nat Commun, 10, 2019
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