Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1926 件

8TDR
DownloadVisualize
BU of 8tdr by Molmil
Crystal structure of the methyltransferase domain of DNMT3A homotetramer
分子名称: DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE
著者Lu, J.W, Song, J.K.
登録日2023-07-04
公開日2024-03-13
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
4PR6
DownloadVisualize
BU of 4pr6 by Molmil
A Second Look at the HDV Ribozyme Structure and Dynamics.
分子名称: HDV RIBOZYME SELF-CLEAVED, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A
著者Kapral, G.J, Jain, S, Noeske, J, Doudna, J.A, Richardson, D.C, Richardson, J.S.
登録日2014-03-05
公開日2014-10-29
最終更新日2014-11-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献New tools provide a second look at HDV ribozyme structure, dynamics and cleavage.
Nucleic Acids Res., 42, 2014
6BRR
DownloadVisualize
BU of 6brr by Molmil
Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites
分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
著者Zhang, Z.M, Song, J.
登録日2017-11-30
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
8TE3
DownloadVisualize
BU of 8te3 by Molmil
Crystal structure of the methyltransferase domain of R882C/R676K DNMT3A homotetramer
分子名称: DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE
著者Lu, J.W, Song, J.K.
登録日2023-07-05
公開日2024-03-13
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
8TE1
DownloadVisualize
BU of 8te1 by Molmil
Crystal structure of the methyltransferase domain of R882H/R676K DNMT3A homotetramer
分子名称: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, L(+)-TARTARIC ACID, ...
著者Lu, J.W, Song, J.K.
登録日2023-07-05
公開日2024-03-13
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
8TE4
DownloadVisualize
BU of 8te4 by Molmil
Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer
分子名称: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE
著者Lu, J.W, Song, J.K.
登録日2023-07-05
公開日2024-03-13
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
9AAT
DownloadVisualize
BU of 9aat by Molmil
X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE
著者Mcphalen, C.A, Vincent, M.G, Jansonius, J.N.
登録日1991-12-02
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase.
J.Mol.Biol., 225, 1992
2GP1
DownloadVisualize
BU of 2gp1 by Molmil
Bacteriophage HK97 Prohead II crystal structure
分子名称: Major capsid protein
著者Gertsman, I, Gan, L, Johnson, J.E.
登録日2006-04-15
公開日2006-05-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (5.2 Å)
主引用文献Structure and Flexibility of Bacteriophage HK97 Pre-expanded State Prohead II
To be Published
1L3L
DownloadVisualize
BU of 1l3l by Molmil
Crystal structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
分子名称: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, 5'-D(*GP*AP*TP*GP*TP*GP*CP*AP*GP*AP*TP*CP*TP*GP*CP*AP*CP*AP*TP*C)-3', Transcriptional activator protein traR
著者Zhang, R, Pappas, T, Brace, J.L, Miller, P.C, Oulmassov, T, Molyneaux, J.M, Anderson, J.C, Bashkin, J.K, Winans, S.C, Joachimiak, A.
登録日2002-02-27
公開日2002-07-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA.
Nature, 417, 2002
3HHA
DownloadVisualize
BU of 3hha by Molmil
Crystal structure of cathepsin L in complex with AZ12878478
分子名称: ACETATE ION, Cathepsin L1, GLYCEROL, ...
著者Asaad, N, Bethel, P.A, Coulson, M.D, Dawson, J, Ford, S.J, Gerhardt, S, Grist, M, Hamlin, G.A, James, M.J, Jones, E.V, Karoutchi, G.I, Kenny, P.W, Morley, A.D, Oldham, K, Rankine, N, Ryan, D, Wells, S.L, Wood, L, Augustin, M, Krapp, S, Simader, H, Steinbacher, S.
登録日2009-05-15
公開日2009-06-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Dipeptidyl nitrile inhibitors of Cathepsin L.
Bioorg.Med.Chem.Lett., 19, 2009
1KWA
DownloadVisualize
BU of 1kwa by Molmil
HUMAN CASK/LIN-2 PDZ DOMAIN
分子名称: HCASK/LIN-2 PROTEIN, SULFATE ION
著者Daniels, D.L, Cohen, A.R, Anderson, J.M, Brunger, A.T.
登録日1998-01-16
公開日1998-05-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
Nat.Struct.Biol., 5, 1998
6BA8
DownloadVisualize
BU of 6ba8 by Molmil
YbtT - Type II thioesterase from Yersiniabactin NRPS/PKS biosynthetic pathway
分子名称: Iron aquisition yersiniabactin synthesis enzyme, YbtT
著者Brett, T.J, Kober, D.L, Ohlemacher, S.I, Henderson, J.P.
登録日2017-10-12
公開日2018-10-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria.
J. Biol. Chem., 293, 2018
4ICG
DownloadVisualize
BU of 4icg by Molmil
N-terminal dimerization domain of H-NS in complex with Hha (Salmonella Typhimurium)
分子名称: DNA-binding protein H-NS, Hemolysin expression modulating protein (Involved in environmental regulation of virulence factors)
著者Ali, S.S, Whitney, J.C, Stevenson, J, Robinson, H, Howell, P.L, Navarre, W.W.
登録日2012-12-10
公開日2013-03-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.9217 Å)
主引用文献Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex.
J.Biol.Chem., 288, 2013
3BX4
DownloadVisualize
BU of 3bx4 by Molmil
Crystal structure of the snake venom toxin aggretin
分子名称: Aggretin alpha chain, Aggretin beta chain, GLYCEROL, ...
著者Hooley, E, Papagrigoriou, E, Navdaev, A, Pandey, A, Clemetson, J.M, Clemetson, K.J, Emsley, J.
登録日2008-01-11
公開日2008-08-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of the platelet activator aggretin reveals a novel (alphabeta)2 dimeric structure.
Biochemistry, 47, 2008
4NPD
DownloadVisualize
BU of 4npd by Molmil
High-resolution structure of C domain of staphylococcal protein A at cryogenic temperature
分子名称: Immunoglobulin G-binding protein A, THIOCYANATE ION, ZINC ION
著者Deis, L.N, Pemble IV, C.W, Oas, T.G, Richardson, J.S, Richardson, D.C.
登録日2013-11-21
公開日2014-10-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity.
Structure, 22, 2014
6I4O
DownloadVisualize
BU of 6i4o by Molmil
Dodecamer DNA containing the synthetic base pair P-Z
分子名称: (DCZ)(DG)(DA)(DT)(DP)(DT)(DA)(DZ)(DA)(DT)(DC)(DG3)
著者Padroni, G, Reichenbach, L.F, Parkinson, J.A, Burley, G.A.
登録日2018-11-10
公開日2019-06-12
最終更新日2024-07-03
実験手法SOLUTION NMR
主引用文献Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components.
J.Am.Chem.Soc., 141, 2019
1M56
DownloadVisualize
BU of 1m56 by Molmil
Structure of cytochrome c oxidase from Rhodobactor sphaeroides (Wild Type)
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, COPPER (II) ION, ...
著者Svensson-Ek, M, Abramson, J, Larsson, G, Tornroth, S, Brezezinski, P, Iwata, S.
登録日2002-07-08
公開日2002-08-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides.
J.Mol.Biol., 321, 2002
5TLQ
DownloadVisualize
BU of 5tlq by Molmil
Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex
分子名称: 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, Thiol:disulfide interchange protein DsbA
著者Mohanty, B, Rimmer, K.A, McMahon, R.M, Headey, S.J, Vazirani, M, Shouldice, S.R, Coincon, M, Tay, S, Morton, C.J, Simpson, J.S, Martin, J.L, Scanlon, M.S.
登録日2016-10-11
公開日2017-04-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1.
PLoS ONE, 12, 2017
8R2C
DownloadVisualize
BU of 8r2c by Molmil
Crystal structure of the Vint domain from Tetrahymena thermophila
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, von willebrand factor type A (VWA) domain was originally protein
著者Iwai, H, Beyer, H.M, Johannson, J.E, Li, M, Wlodawer, A.
登録日2023-11-03
公開日2024-02-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The three-dimensional structure of the Vint domain from Tetrahymena thermophila suggests a ligand-regulated cleavage mechanism by the HINT fold.
Febs Lett., 598, 2024
7E4K
DownloadVisualize
BU of 7e4k by Molmil
WNV envelope protein
分子名称: Core protein
著者Xiao, H, Qi, J, Huang, C, Song, J, Cheng, H.
登録日2021-02-13
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献WNV envelope protein
To Be Published
4NPF
DownloadVisualize
BU of 4npf by Molmil
High-resolution structure of two tandem B domains of staphylococcal protein A connected by the conserved linker
分子名称: Immunoglobulin G-binding protein A
著者Deis, L.N, Pemble IV, C.W, Oas, T.G, Richardson, J.S, Richardson, D.C.
登録日2013-11-21
公開日2014-10-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity.
Structure, 22, 2014
6I4N
DownloadVisualize
BU of 6i4n by Molmil
Dodecamer DNA containing the synthetic base pair P-Z in complex with a pyrrole-imidazole polyamide
分子名称: 3-[3-[[4-[[4-[[4-[[4-[[(2~{R})-2-azaniumyl-4-[[1-methyl-4-[[1-methyl-4-[[1-methyl-4-[(1-methylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]butanoyl]amino]-1-methyl-imidazol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]propanoylamino]propyl-dimethyl-azanium, DNA (5'-D(*CP*GP*AP*TP*(DP)P*TP*AP*(DZ)P*AP*TP*CP*G)-3')
著者Padroni, G, Parkison, J, Burley, G.A.
登録日2018-11-10
公開日2019-06-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components.
J.Am.Chem.Soc., 141, 2019
7DXO
DownloadVisualize
BU of 7dxo by Molmil
The mutant of bifunctional thioesterase catalyzing epimerization and cyclization
分子名称: Non-ribosomal peptide synthetase 4
著者Yu, J.H, Song, J, Chi, C.B, Ma, M.
登録日2021-01-19
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional Characterization and Crystal Structure of the Bifunctional Thioesterase Catalyzing Epimerization and Cyclization in Skyllamycin Biosynthesis
Acs Catalysis, 11, 2021
3Q6F
DownloadVisualize
BU of 3q6f by Molmil
Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120
分子名称: DI(HYDROXYETHYL)ETHER, Heavy chain of Fab of human mAb 2909, Light chain of Fab of human mAb 2909
著者Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P.
登録日2010-12-31
公開日2011-05-25
最終更新日2011-10-12
実験手法X-RAY DIFFRACTION (3.192 Å)
主引用文献Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
7KW7
DownloadVisualize
BU of 7kw7 by Molmil
Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR
分子名称: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ...
著者Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A.
登録日2020-11-30
公開日2021-12-08
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism.
Nature, 601, 2022

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon