7FER
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![BU of 7fer by Molmil](/molmil-images/mine/7fer) | Cryo-EM structure of BsClpP-ADEP1 complex at pH 4.2 | Descriptor: | ADEP1, ATP-dependent Clp protease proteolytic subunit | Authors: | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | Deposit date: | 2021-07-21 | Release date: | 2022-07-06 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. Embo J., 41, 2022
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2OPN
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![BU of 2opn by Molmil](/molmil-images/mine/2opn) | Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527 | Descriptor: | Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)], MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Cao, R, Gao, Y.G, Robinson, H, Goddard, A, Oldfield, E. | Deposit date: | 2007-01-29 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Bisphosphonates: Teaching Old Drugs with New Tricks To be Published
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7FEP
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![BU of 7fep by Molmil](/molmil-images/mine/7fep) | Cryo-EM structure of BsClpP-ADEP1 complex at pH 6.5 | Descriptor: | ADEP1, ATP-dependent Clp protease proteolytic subunit | Authors: | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | Deposit date: | 2021-07-21 | Release date: | 2022-07-06 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. Embo J., 41, 2022
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2OUP
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![BU of 2oup by Molmil](/molmil-images/mine/2oup) | crystal structure of PDE10A | Descriptor: | MAGNESIUM ION, ZINC ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Authors: | Wang, H.C, Liu, Y.D, Hou, J, Zheng, M.Y, Robinson, H. | Deposit date: | 2007-02-12 | Release date: | 2007-03-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | From the Cover: Structural insight into substrate specificity of phosphodiesterase 10. Proc.Natl.Acad.Sci.Usa, 104, 2007
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4IZ7
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![BU of 4iz7 by Molmil](/molmil-images/mine/4iz7) | |
4OZW
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![BU of 4ozw by Molmil](/molmil-images/mine/4ozw) | |
4KNC
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![BU of 4knc by Molmil](/molmil-images/mine/4knc) | Structural and functional characterization of Pseudomonas aeruginosa AlgX | Descriptor: | Alginate biosynthesis protein AlgX | Authors: | Riley, L.M, Weadge, J.T, Baker, P, Robinson, H, Codee, J.D.C, Tipton, P.A, Ohman, D.E, Howell, P.L. | Deposit date: | 2013-05-09 | Release date: | 2013-06-26 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.141 Å) | Cite: | Structural and Functional Characterization of Pseudomonas aeruginosa AlgX: ROLE OF AlgX IN ALGINATE ACETYLATION. J.Biol.Chem., 288, 2013
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5EXT
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![BU of 5ext by Molmil](/molmil-images/mine/5ext) | |
5EXS
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![BU of 5exs by Molmil](/molmil-images/mine/5exs) | |
5EXX
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![BU of 5exx by Molmil](/molmil-images/mine/5exx) | AAA+ ATPase FleQ from Pseudomonas aeruginosa bound to c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), SULFATE ION, Transcriptional regulator FleQ | Authors: | Navarro, M.V.A.S, Sondermann, H, Krasteva, P.V. | Deposit date: | 2015-11-24 | Release date: | 2016-02-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.311 Å) | Cite: | Mechanistic insights into c-di-GMP-dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa. Proc.Natl.Acad.Sci.USA, 113, 2016
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2QYK
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![BU of 2qyk by Molmil](/molmil-images/mine/2qyk) | Crystal structure of PDE4A10 in complex with inhibitor NPV | Descriptor: | 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid, Cyclic AMP-specific phosphodiesterase HSPDE4A10, MAGNESIUM ION, ... | Authors: | Wang, H, Peng, M, Chen, Y, Geng, J, Robinson, H, Houslay, M. | Deposit date: | 2007-08-15 | Release date: | 2008-04-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors. Biochem.J., 408, 2007
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212D
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![BU of 212d by Molmil](/molmil-images/mine/212d) | INFLUENCE OF COUNTER-IONS ON THE CRYSTAL STRUCTURES OF DNA DECAMERS: BINDING OF [CO(NH3)6]3+ AND BA2+ TO A-DNA | Descriptor: | COBALT HEXAMMINE(III), DNA (5'-D(*AP*CP*CP*GP*GP*CP*CP*GP*GP*T)-3') | Authors: | Gao, Y.-G, Robinson, H, Van Boom, J.H, Wang, A.H.-J. | Deposit date: | 1995-06-26 | Release date: | 1996-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Influence of counter-ions on the crystal structures of DNA decamers: binding of [Co(NH3)6]3+ and Ba2+ to A-DNA. Biophys.J., 69, 1995
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3HVA
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![BU of 3hva by Molmil](/molmil-images/mine/3hva) | |
2OUR
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![BU of 2our by Molmil](/molmil-images/mine/2our) | crystal structure of PDE10A2 mutant D674A in complex with cAMP | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MAGNESIUM ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Authors: | Wang, H.C, Liu, Y.D, Hou, J, Zheng, M.Y, Robinson, H. | Deposit date: | 2007-02-12 | Release date: | 2007-03-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | From the Cover: Structural insight into substrate specificity of phosphodiesterase 10. Proc.Natl.Acad.Sci.Usa, 104, 2007
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5FR3
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![BU of 5fr3 by Molmil](/molmil-images/mine/5fr3) | X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E) | Descriptor: | CALCIUM ION, GLYCEROL, PROTECTIVE ANTIGEN | Authors: | Ganesan, A, Siekierska, A, Beerten, J, Brams, M, van Durme, J, De Baets, G, van der Kant, R, Gallardo, R, Ramakers, M, Langenberg, T, Wilkinson, H, De Smet, F, Ulens, C, Rousseau, F, Schymkowitz, J. | Deposit date: | 2015-12-15 | Release date: | 2016-01-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.935 Å) | Cite: | Structural Hot Spots for the Solubility of Globular Proteins Nat.Commun., 7, 2016
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220D
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![BU of 220d by Molmil](/molmil-images/mine/220d) | INFLUENCE OF COUNTER-IONS ON THE CRYSTAL STRUCTURES OF DNA DECAMERS: BINDING OF [CO(NH3)6]3+ AND BA2+ TO A-DNA | Descriptor: | BARIUM ION, DNA (5'-D(*AP*CP*CP*CP*GP*CP*GP*GP*GP*T)-3') | Authors: | Gao, Y.-G, Robinson, H, Van Boom, J.H, Wang, A.H.-J. | Deposit date: | 1995-06-26 | Release date: | 1996-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Influence of counter-ions on the crystal structures of DNA decamers: binding of [Co(NH3)6]3+ and Ba2+ to A-DNA. Biophys.J., 69, 1995
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221D
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1B5L
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![BU of 1b5l by Molmil](/molmil-images/mine/1b5l) | OVINE INTERFERON TAU | Descriptor: | INTERFERON TAU, SULFATE ION | Authors: | Radhakrishnan, R, Walter, L.J, Subramaniam, P.S, Johnson, H.J, Walter, M.R. | Deposit date: | 1999-01-07 | Release date: | 1999-05-18 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of ovine interferon-tau at 2.1 A resolution. J.Mol.Biol., 286, 1999
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3NIN
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![BU of 3nin by Molmil](/molmil-images/mine/3nin) | The structure of UBR box (RLGES) | Descriptor: | E3 ubiquitin-protein ligase UBR1, Peptide RLGES, ZINC ION | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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2EW4
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![BU of 2ew4 by Molmil](/molmil-images/mine/2ew4) | Solution structure of MrIA | Descriptor: | MrIA | Authors: | Nilsson, K.P, Lovelace, E.S, Caesar, C.E, Tynngard, N, Alewood, P.F, Johansson, H.M, Sharpe, I.A, Lewis, R.J, Daly, N.L, Craik, D.J. | Deposit date: | 2005-11-02 | Release date: | 2005-11-15 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter Biopolymers, 80, 2005
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2FM0
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![BU of 2fm0 by Molmil](/molmil-images/mine/2fm0) | Crystal structure of PDE4D in complex with L-869298 | Descriptor: | (S)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHY L)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ... | Authors: | Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H. | Deposit date: | 2006-01-06 | Release date: | 2006-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase J.Med.Chem., 49, 2006
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2FM5
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![BU of 2fm5 by Molmil](/molmil-images/mine/2fm5) | Crystal structure of PDE4D2 in complex with inhibitor L-869299 | Descriptor: | (R)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHYL)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ... | Authors: | Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H. | Deposit date: | 2006-01-07 | Release date: | 2006-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase J.Med.Chem., 49, 2006
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3PD6
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![BU of 3pd6 by Molmil](/molmil-images/mine/3pd6) | Crystal structure of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV | Descriptor: | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase, ... | Authors: | Han, Q, Robinson, H, Cai, T, Tagle, D.A, Li, J. | Deposit date: | 2010-10-22 | Release date: | 2010-11-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV. Biosci.Rep., 31, 2011
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3PDB
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![BU of 3pdb by Molmil](/molmil-images/mine/3pdb) | Crystal structure of mouse mitochondrial aspartate aminotransferase in complex with oxaloacetic acid | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase, mitochondrial, ... | Authors: | Han, Q, Robinson, H, Cai, T, Tagle, D.A, Li, J. | Deposit date: | 2010-10-22 | Release date: | 2010-11-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV. Biosci.Rep., 31, 2011
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2RGJ
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![BU of 2rgj by Molmil](/molmil-images/mine/2rgj) | Crystal structure of flavin-containing monooxygenase PhzS | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase | Authors: | Ladner, J.E, Parsons, J.F, Greenhagen, B.T, Robinson, H. | Deposit date: | 2007-10-03 | Release date: | 2008-05-20 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Pyocyanin Biosynthetic Protein PhzS. Biochemistry, 47, 2008
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