5IQQ
 
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6S8B
 | | Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1 | | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | 著者 | Sofos, N, Montoya, G, Stella, S. | | 登録日 | 2019-07-09 | | 公開日 | 2020-07-08 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
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6S91
 | | Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2 | | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | 著者 | Sofos, N, Montoya, G, Stella, S. | | 登録日 | 2019-07-11 | | 公開日 | 2020-07-08 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
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6S8E
 | | Cryo-EM structure of the type III-B Cmr-beta complex bound to non-cognate target RNA | | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | 著者 | Sofos, N, Montoya, G, Stella, S. | | 登録日 | 2019-07-09 | | 公開日 | 2020-07-08 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
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6SH8
 | | Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2, in the presence of ssDNA | | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | 著者 | Sofos, N, Montoya, G, Stella, S. | | 登録日 | 2019-08-06 | | 公開日 | 2020-07-08 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
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6S6B
 | | Type III-B Cmr-beta Cryo-EM structure of the Apo state | | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | 著者 | Sofos, N, Montoya, G, Stella, S. | | 登録日 | 2019-07-02 | | 公開日 | 2020-07-08 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
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6SIC
 | | Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA | | 分子名称: | CRISPR-associated RAMP protein, Cmr1 family, Cmr4 family, ... | | 著者 | Sofos, N, Montoya, G, Stella, S. | | 登録日 | 2019-08-09 | | 公開日 | 2020-07-08 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
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6SHB
 | | Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1, in the presence of ssDNA | | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | | 著者 | Sofos, N, Montoya, G, Stella, S. | | 登録日 | 2019-08-06 | | 公開日 | 2020-07-08 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
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7ODF
 | | Structure of the mini-RNA-guided endonuclease CRISPR-Cas_phi3 | | 分子名称: | Cas_phi3, DNA (5'-D(P*GP*G)-3'), DNA (5'-D(P*GP*TP*AP*AP*TP*TP*CP*AP*G)-3'), ... | | 著者 | Carabias del Rey, A, Fugilsang, A, Temperini, P, Pape, T, Sofos, N, Stella, S, Erledsson, S, Montoya, G. | | 登録日 | 2021-04-29 | | 公開日 | 2021-07-21 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3.
Nat Commun, 12, 2021
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8AXA
 | | Cryo-EM structure of shCas12k-sgRNA-dsDNA ternary complex (type V-K CRISPR-associated transposon) | | 分子名称: | Cas12k, DNA non-target strand, DNA target strand, ... | | 著者 | Tenjo-Castano, F, Sofos, N, Stella, S, Fuglsang, A, Pape, T, Mesa, P, Stutzke, L.S, Temperini, P, Montoya, G. | | 登録日 | 2022-08-31 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Conformational Landscape of the Type V-K CRISPR-associated Transposon Integration Assembly
To Be Published
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8AXB
 | | Cryo-EM structure of Cas12k-sgRNA binary complex (type V-K CRISPR-associated transposon) | | 分子名称: | Cas12k, sgRNA | | 著者 | Tenjo-Castano, F, Sofos, N, Stella, S, Molina, R, Pape, T, Lopez-Mendez, B, Stutzke, L.S, Temperini, P, Montoya, G. | | 登録日 | 2022-08-31 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Structural prediction of the Cas12k interaction with the transposon pre-integration complex
To Be Published
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4FXE
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4FXI
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4FXH
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7Z18
 | | E. coli C-P lyase bound to a PhnK ABC dimer and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, ... | | 著者 | Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | | 登録日 | 2022-02-24 | | 公開日 | 2022-05-25 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (1.98 Å) | | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
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7Z19
 | | E. coli C-P lyase bound to a single PhnK ABC domain | | 分子名称: | Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... | | 著者 | Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | | 登録日 | 2022-02-24 | | 公開日 | 2022-05-25 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
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7Z17
 | | E. coli C-P lyase bound to a PhnK ABC dimer in an open conformation | | 分子名称: | Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... | | 著者 | Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | | 登録日 | 2022-02-24 | | 公開日 | 2022-05-25 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
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7Z15
 | | E. coli C-P lyase bound to a PhnK/PhnL dual ABC dimer and ADP + Pi | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, ... | | 著者 | Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. | | 登録日 | 2022-02-24 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (1.93 Å) | | 主引用文献 | Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
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8AA5
 | | Cryo-EM structure of the strand transfer complex of the TnsB transposase (type V-K CRISPR-associated transposon) | | 分子名称: | LE_PolyA, LE_Target, RE_PolyA, ... | | 著者 | Tenjo-Castano, F, Sofos, N, Lopez-Mendez, B, Stutzke, L.S, Fuglsang, A, Stella, S, Montoya, G. | | 登録日 | 2022-06-30 | | 公開日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | | 主引用文献 | Structure of the TnsB transposase-DNA complex of type V-K CRISPR-associated transposon.
Nat Commun, 13, 2022
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6QZT
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6R7B
 | | Crystal structure of Csx1 in complex with cyclic oligoadenylate cOA4 conformation 1 | | 分子名称: | CRISPR-associated (Cas) DxTHG family, RNA (5'-R(P*AP*AP*AP*A)-3') | | 著者 | Molina, R, Montoya, G, Sofos, N, Stella, S. | | 登録日 | 2019-03-28 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | Structure of Csx1-cOA4complex reveals the basis of RNA decay in Type III-B CRISPR-Cas.
Nat Commun, 10, 2019
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6QZQ
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6R9R
 | | Crystal structure of Csx1 in complex with cyclic oligoadenylate cOA4 conformation 2 | | 分子名称: | CRISPR-associated (Cas) DxTHG family, circular RNA (5'-R(P*AP*AP*AP*A)-3') | | 著者 | Molina, R, Montoya, G, Sofos, N, Stella, S. | | 登録日 | 2019-04-03 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of Csx1-cOA4complex reveals the basis of RNA decay in Type III-B CRISPR-Cas.
Nat Commun, 10, 2019
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